Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/51051
DC FieldValueLanguage
dc.contributor.authorRomero, J. C.en_US
dc.contributor.authorSantolaria, F.en_US
dc.contributor.authorGonzález-Reimers, E.en_US
dc.contributor.authorDìaz-Flores, L.en_US
dc.contributor.authorConde, A.en_US
dc.contributor.authorRodriguez-Moreno, F.en_US
dc.contributor.authorBatista, N.en_US
dc.date.accessioned2018-11-24T20:59:00Z-
dc.date.available2018-11-24T20:59:00Z-
dc.date.issued1994en_US
dc.identifier.issn0741-8329en_US
dc.identifier.urihttp://hdl.handle.net/10553/51051-
dc.description.abstractTo investigate the prevalence of alcoholic myopathy and its relationship to the nutritional status, we performed a muscle biopsy on the vastum lateralis of 60 consecutive hospitalized alcoholic patients using a Tru-Cut needle, processing it for light microscope and ultrastructural analysis. The nutritional status was assessed by anthropometric measurements such as midarm circumference, triceps skinfold and midarm muscle area, and serum albumin. The hallmark of chronic alcoholic myopathy, fiber muscle atrophy, was present in 33% of the patients, necrosis scarcely being observed (1.5%). Ultrastructural alterations as lipid and glycogen accumulation or mitochondrial and myofibrillar alterations were nonspecific and observed in nearly all the cases where atrophy was present. Malnutrition was frequent in our patients: 39% and 34% showed a triceps skinfold and a midarm muscle area, respectively, under the fifth populational percentile. Patients with muscle fiber atrophy or ultrastructural changes showed a worse nutritional status, not only regarding muscle protein (assessed by midarm muscle area or creatininuria and explained by fiber atrophy), but also regarding fat stores assessed by triceps skinfold. Toxic effect of ethanol and malnutrition may act synergistically leading to chronic alcoholic myopathy.en_US
dc.languageengen_US
dc.relation.ispartofAlcoholen_US
dc.sourceAlcohol[ISSN 0741-8329],v. 11(6), p. 549-555 (Noviembre-Diciembre 1994)en_US
dc.subject32 Ciencias médicasen_US
dc.subject3201 Ciencias clínicasen_US
dc.subject611301 Alcoholismoen_US
dc.subject.otherAlcoholismen_US
dc.subject.otherMalnutritionen_US
dc.subject.otherAnthropometryen_US
dc.subject.otherMuscle fiber atrophyen_US
dc.subject.otherChronic myopathyen_US
dc.titleChronic alcoholic myopathy and nutritional statusen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/0741-8329(94)90082-5en_US
dc.identifier.scopus0027993202-
dc.contributor.authorscopusid56363986200-
dc.contributor.authorscopusid6701348569-
dc.contributor.authorscopusid7004694989-
dc.contributor.authorscopusid7004901441-
dc.contributor.authorscopusid7004460826-
dc.contributor.authorscopusid6603811887-
dc.contributor.authorscopusid6701702202-
dc.description.lastpage555en_US
dc.description.firstpage549en_US
dc.relation.volume11en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.numberofpages7en_US
dc.utils.revisionen_US
dc.date.coverdateNoviembre-diciembre 1994en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.scieSCIE-
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptGIR IUIBS: Patología médica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-2540-3880-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameConde Martel, Alicia-
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