Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50918
DC FieldValueLanguage
dc.contributor.authorGonzález-Alonso, Joséen_US
dc.contributor.authorCalbet, Jose A. L.en_US
dc.contributor.authorBoushel, Roberten_US
dc.contributor.authorHelge, Jørn W.en_US
dc.contributor.authorSøndergaard, Hansen_US
dc.contributor.authorMunch-Andersen, Thoren_US
dc.contributor.authorvan Hall, Gerriten_US
dc.contributor.authorMortensen, Stefan P.en_US
dc.contributor.authorSecher, Niels H.en_US
dc.contributor.otherCalbet, Jose A-
dc.contributor.otherHelge, Jorn-
dc.contributor.othervan Hall, Gerrit-
dc.contributor.otherMortensen, Stefan-
dc.date.accessioned2018-11-24T19:54:42Z-
dc.date.available2018-11-24T19:54:42Z-
dc.date.issued2015en_US
dc.identifier.issn0958-0670en_US
dc.identifier.urihttp://hdl.handle.net/10553/50918-
dc.description.abstractNew Findings What is the central question of this study?Temperature-sensitive mechanisms are thought to contribute to blood-flow regulation, butthe relationship between exercising and non-exercising limb perfusion and blood temperatureis not established. What is the main finding and its importance?The close coupling among perfusion, blood temperature and aerobic metabolism in exercisingand non-exercising extremities across different exercise modalities and activity levels and thetight association between limb vasodilatation and increases in plasma ATP suggest that bothtemperature- and metabolism-sensitive mechanisms are important for the control of humanlimb perfusion, possibly by activating ATP release from the erythrocytes.Temperature-sensitive mechanisms may contribute to blood-flow regulation, but the influenceof temperature on perfusion to exercising and non-exercising human limbs is not established.Blood temperature (TB),bloodflowandoxygenuptake( ̇VO2)inthelegsandarmsweremeasuredin 16 healthy humans during 90 min of leg and arm exercise and during exhaustive incrementalleg or arm exercise. During prolonged exercise, leg blood flow (LBF) was fourfold higher thanarm blood flow (ABF) in association with higherTBand limb ̇VO2.Leg and arm vascularconductance during exercise compared with rest was related closely toTB(r2=0.91;P<0.05),plasma ATP (r2=0.94;P<0.05) and limb ̇VO2(r2=0.99;P<0.05). During incrementalleg exercise, LBF increased in association with elevations inTBand limb ̇VO2,whereas ABF,armTBand ̇VO2remained largely unchanged. During incremental arm exercise, both ABFand LBF increased in relationship to similar increases in ̇VO2.In 12 trained males, increasesin femoralTBand LBF during incremental leg exercise were mirrored by similar pulmonaryarteryTBand cardiac output dynamics, suggesting that processes in active limbs dominatecentral temperature and perfusion responses. The present data reveal a close coupling amongperfusion,TBand aerobic metabolism in exercising and non-exercising extremities and a tighten_US
dc.languageengen_US
dc.publisher0958-0670-
dc.relation.ispartofExperimental Physiologyen_US
dc.sourceExperimental Physiology[ISSN 0958-0670],v. 100 (10), p. 1118-1131en_US
dc.subject241106 Fisiología del ejercicioen_US
dc.subject.otherHuman Skeletal-Muscle
dc.subject.otherWhole-Body Exercise
dc.subject.otherMaximal Exercise
dc.subject.otherHuman Forearm
dc.subject.otherAdenosine-Triphosphate
dc.subject.otherHemodynamic-Responses
dc.subject.otherHuman Erythrocytes
dc.subject.otherDynamic Exercise
dc.subject.otherVenous Effluent
dc.subject.otherOxygen Delivery
dc.titleBlood temperature and perfusion to exercising and non-exercising human limbsen_US
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.doi10.1113/EP085383
dc.identifier.scopus84943360625-
dc.identifier.isi000362646000002-
dcterms.isPartOfExperimental Physiology-
dcterms.sourceExperimental Physiology[ISSN 0958-0670],v. 100 (10), p. 1118-1131-
dc.contributor.authorscopusid7004397216-
dc.contributor.authorscopusid7004323423-
dc.contributor.authorscopusid7003471688-
dc.contributor.authorscopusid20334409300-
dc.contributor.authorscopusid36958968500-
dc.contributor.authorscopusid20735070800-
dc.contributor.authorscopusid57191983922-
dc.contributor.authorscopusid8591187800-
dc.contributor.authorscopusid7102380830-
dc.description.lastpage1131-
dc.description.firstpage1118-
dc.relation.volume100-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000362646000002-
dc.contributor.daisngid9620399-
dc.contributor.daisngid326233
dc.contributor.daisngid90295-
dc.contributor.daisngid220476-
dc.contributor.daisngid147585-
dc.contributor.daisngid1592176-
dc.contributor.daisngid3384687-
dc.contributor.daisngid209461-
dc.contributor.daisngid512474-
dc.contributor.daisngid9787-
dc.identifier.investigatorRIDH-6693-2015-
dc.identifier.investigatorRIDI-7096-2012-
dc.identifier.investigatorRIDNo ID-
dc.identifier.investigatorRIDNo ID-
dc.contributor.wosstandardWOS:Gonzalez-Alonso, J
dc.contributor.wosstandardWOS:Calbet, JAL
dc.contributor.wosstandardWOS:Boushel, R
dc.contributor.wosstandardWOS:Helge, JW
dc.contributor.wosstandardWOS:Sondergaard, H
dc.contributor.wosstandardWOS:Munch-Andersen, T
dc.contributor.wosstandardWOS:van Hall, G
dc.contributor.wosstandardWOS:Mortensen, SP
dc.contributor.wosstandardWOS:Secher, NH
dc.date.coverdateOctubre 2015
dc.identifier.ulpgces
dc.description.sjr1,412
dc.description.jcr2,818
dc.description.sjrqQ2
dc.description.jcrqQ2
dc.description.scieSCIE
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptGIR IUIBS: Rendimiento humano, ejercicio físico y salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Educación Física-
crisitem.author.orcid0000-0002-9215-6234-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameLópez Calbet, José Antonio-
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