Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/50254
Campo DC Valoridioma
dc.contributor.authorBlanco, Carlosen_US
dc.contributor.authorOrtega, Nancyen_US
dc.contributor.authorCastillo, Rodolfoen_US
dc.contributor.authorAlvarez, Maríaen_US
dc.contributor.authorDumpierrez, Antonio G.en_US
dc.contributor.authorCarrillo, Teresaen_US
dc.date.accessioned2018-11-24T14:36:33Z-
dc.date.available2018-11-24T14:36:33Z-
dc.date.issued1998en_US
dc.identifier.issn1081-1206en_US
dc.identifier.urihttp://hdl.handle.net/10553/50254-
dc.description.abstractCarica papaya (CP) trees are widely cultivated in tropical and subtropical areas; however, CP pollen allergy has not been previously described. Objective To study patients with CP pollen hypersensitivity. Methods A CP pollen extract was elaborated. Skin prick tests (SPTs) with this extract, as well as with commercial papaya fruit and papain extracts, were performed. Specific IgE levels to CP pollen, papaya fruit, and papain were determined. Specific conjunctival challenge tests to the CP pollen extract were also performed. RAST inhibition studies among CP pollen, papaya fruit, and papain were carried out. Twenty atopic patients were used as a control group for in vivo and in vitro tests. Results Six patients with clnical histories of seasonal rhinoconjunctivitis or bronchial asthma in relation to CP trees exposure, suggestive of IgE-mediated respiratory allergy, were studied. Commercial SPT and specific serum IgE to papaya fruit and papain were positive in our patients. An IgE-mediated hypersensitivity to a CP pollen extract was demonstrated in all patients, by means of SPTs, specific serum IgE determinations, and conjunctival challenge tests. Control atopic subjects showed negative SPTs, specific IgE, and conjunctival challenge tests to the CP pollen extract. On RAST inhibition studies using CP pollen extract in solid phase, a significant crossreactivity was found among CP pollen, papaya fruit, and papain. Conclusions Our study suggests that papaya flower pollen is able to induce respiratory IgE-mediated allergy. The existence of common allergens among papaya flower pollen, papaya fruit, and papain has been demonstrated by RAST inhibition.en_US
dc.languageengen_US
dc.relation.ispartofAnnals of Allergy, Asthma and Immunologyen_US
dc.sourceAnnals of Allergy, Asthma and Immunology[ISSN 1081-1206],v. 81(2), p. 171-175 (Agosto 1998)en_US
dc.subject32 Ciencias médicasen_US
dc.subject320701 Alergiasen_US
dc.subject.otherCarica papayaen_US
dc.subject.otherPollenen_US
dc.subject.otherHypersensitivityen_US
dc.subject.otherRAST inhibitionen_US
dc.titleCarica papaya pollen allergyen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/S1081-1206(10)62805-0en_US
dc.identifier.scopus0031659476-
dc.contributor.authorscopusid57189070218-
dc.contributor.authorscopusid7004458460-
dc.contributor.authorscopusid7202163438-
dc.contributor.authorscopusid8121090100-
dc.contributor.authorscopusid6505885903-
dc.contributor.authorscopusid7003526269-
dc.description.lastpage175en_US
dc.description.firstpage171en_US
dc.relation.volume81en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.numberofpages5en_US
dc.utils.revisionen_US
dc.date.coverdateAgosto 1998en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.jcr1,674-
dc.description.jcrqQ1-
dc.description.scieSCIE-
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptGIR IUIBS: Patología médica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-3047-8908-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameCarrillo Díaz, Teresa-
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