Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/50156
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dc.contributor.authorCañizares, Miguel A.en_US
dc.contributor.authorMatilla, J. M.en_US
dc.contributor.authorCueto, A.en_US
dc.contributor.authorAlgar, J.en_US
dc.contributor.authorMuguruza, I.en_US
dc.contributor.authorMoreno-Mata, N.en_US
dc.contributor.authorMoreno-Balsalobre, R.en_US
dc.contributor.authorGuijarro, R.en_US
dc.contributor.authorArrabal, R.en_US
dc.contributor.authorGarcia-Fontan, E.en_US
dc.contributor.authorGonzalez-Pinẽiro, A.en_US
dc.contributor.authorGarcia-Yuste, M.en_US
dc.contributor.authorMatilla, Jose Mariaen_US
dc.contributor.authorHeras, Felixen_US
dc.contributor.authorBorrego, Henaren_US
dc.contributor.authorEscobar, Ignacioen_US
dc.contributor.authorMoya, Joanen_US
dc.contributor.authorLago, Juanen_US
dc.contributor.authorSaldaña, Daviden_US
dc.contributor.authorGarrido, Pilaren_US
dc.contributor.authorCerezo, Franciscoen_US
dc.contributor.authorGonzalez-Aragoneses, Federicoen_US
dc.contributor.authorSimon, Carlosen_US
dc.contributor.authorAlvarez, Emilioen_US
dc.contributor.authorCebollero, Mariaen_US
dc.contributor.authorRodriguez-Paniagua, Jose Manuelen_US
dc.contributor.authorArnau, Antonioen_US
dc.contributor.authorLopez-Rivero, Luisen_US
dc.contributor.authorQuevedo, Santiagoen_US
dc.contributor.authorCamacho, Maria Carmenen_US
dc.contributor.authorAstudillo, Julioen_US
dc.contributor.authorPerez, Javieren_US
dc.contributor.authorMolins, Laureanoen_US
dc.contributor.authorMier, Jose Manuelen_US
dc.contributor.authorSanchez-Palencia, Abelen_US
dc.contributor.authorConcha, Angelen_US
dc.contributor.authorFreixinet, Jorgeen_US
dc.contributor.authorRodriguez, Pedroen_US
dc.contributor.authorRomero, Teresaen_US
dc.contributor.authorTorres, Juanen_US
dc.contributor.authorBermejo, Juanen_US
dc.contributor.authorMoreno, Nicolasen_US
dc.contributor.authorBlanco, Anaen_US
dc.contributor.authorBorro, Jose Mariaen_US
dc.contributor.authorDe-la-Torre, Mercedesen_US
dc.contributor.authorCapdevilla, Anaen_US
dc.contributor.authorMoreno, Ramonen_US
dc.contributor.authorSerra, Mireiaen_US
dc.contributor.authorRami-Porta, Ramonen_US
dc.contributor.authorBenitez, Antonioen_US
dc.contributor.authorVarela, Andresen_US
dc.contributor.authorCordoba, Maren_US
dc.contributor.authorBlanco-Ramos, Montserraten_US
dc.contributor.authorZapatero, Joséen_US
dc.contributor.authorRivas, Juan Joseen_US
dc.contributor.authorMenal, Patriciaen_US
dc.contributor.authorGalan, Genaroen_US
dc.contributor.authorAnsotegui, Emilioen_US
dc.date.accessioned2018-11-24T13:48:10Z-
dc.date.available2018-11-24T13:48:10Z-
dc.date.issued2014en_US
dc.identifier.issn0040-6376en_US
dc.identifier.urihttp://hdl.handle.net/10553/50156-
dc.description.abstractBackground Atypical carcinoids (AC) of the lung are rare intermediate-grade neuroendocrine neoplasms. Prognostic factors for these tumours are undefined. Methods Our cooperative group retrieved data on 127 patients operated between 1980 and 2009 because of an AC. Several clinical and pathological features were studied. Results In a univariable analysis, T-status (p=0.005), N-status (p=0.021), preoperative M-status (previously treated) (p=0.04), and distant recurrence developed during the outcome (p<0.001) presented statistically significant differences related to survival of these patients. In a multivariable analysis, only distant recurrence was demonstrated to be an independent risk factor for survival (p<0.001; HR: 13.1). During the monitoring, 25.2% of the patients presented some kind of recurrence. When we studied recurrence factors in a univariable manner, sublobar resections presented significant relationship with locoregional recurrence (p<0.001). In the case of distant recurrence, T and N status presented significant differences. Patients with preoperative M1 status presented higher frequencies of locoregional and distant recurrence (p=0.004 and p<0.001, respectively). In a multivariable analysis, sublobar resection was an independent prognostic factor to predict locoregional recurrence (p=0.002; HR: 18.1). Conclusions Complete standard surgical resection with radical lymphadenectomy is essential for AC. Sublobar resections are related to locoregional recurrence, so they should be avoided except for carefully selected patients. Nodal status is an important prognostic factor to predict survival and recurrence. Distant recurrence is related to poor outcome.en_US
dc.languageengen_US
dc.relation.ispartofThoraxen_US
dc.sourceThorax[ISSN 0040-6376],v. 69, p. 648-653 (Junio 2014)en_US
dc.subject32 Ciencias médicasen_US
dc.subject320713 Oncologíaen_US
dc.subject.otherCarcinoid tumoursen_US
dc.subject.otherLungen_US
dc.subject.otherNeoplasmen_US
dc.titleAtypical carcinoid tumours of the lung: Prognostic factors and patterns of recurrenceen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1136/thoraxjnl-2013-204102en_US
dc.identifier.scopus84902276603-
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dc.description.lastpage653en_US
dc.description.firstpage648en_US
dc.relation.volume69en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.numberofpages6en_US
dc.utils.revisionen_US
dc.date.coverdateJunio 2014en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr3,623-
dc.description.jcr8,29-
dc.description.sjrqQ1-
dc.description.jcrqQ1-
dc.description.scieSCIE-
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Patología médica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-7163-6853-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameFreixinet Gilart, Jorge Lorenzo-
Colección:Artículos
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