Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/50143
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dc.contributor.authorMuniain, M. A.en_US
dc.contributor.authorRodríguez, M. D.en_US
dc.contributor.authorRomero, A.en_US
dc.contributor.authorMata, R.en_US
dc.contributor.authorVargas, C.en_US
dc.contributor.authorNaranjo, A.en_US
dc.contributor.otherNaranjo Hernandez, Antonio-
dc.contributor.otherMata, Rosario-
dc.date.accessioned2018-11-24T13:40:01Z-
dc.date.available2018-11-24T13:40:01Z-
dc.date.issued1991en_US
dc.identifier.issn1462-0324en_US
dc.identifier.urihttp://hdl.handle.net/10553/50143-
dc.description.abstractPatients with rheumatoid arthritis (RA) experience fluctuations of symptoms throughout the day. These could be due to mechanical changes or modification of the inflammatory mechanisms. In the present paper we studied fluctuations of superoxide production (02), enzyme release ( and lyso zyme) and neutrophil aggregation in the peripheral blood of eight healthy volunteers and eight patients with RA. Although enzyme release was greater in patients with RA, no significant difference was found throughout the day, neither in control nor in patients. Similar results were obtained when studying neutrophil aggregation. On the contrary, the superoxide production, determined at 8:00, 14:00 and 20:00 h, was 6.3 ± 0.5, 4.40±0.4 and 6.26±0.3, respectively, in patients with RA and 6.65±0.7, 4.7±0.7 and 7.27±0.4 in the controls. The values obtained at 14:00 h were significantly lower (α=0.01). There were no differences in the curve form between patients and controls.en_US
dc.languagespaen_US
dc.publisher1462-0324-
dc.relation.ispartofRheumatologyen_US
dc.sourceRheumatology [ISSN 1462-0324, ],v. 30 (2), p. 138-140en_US
dc.subject320509 Reumatologíaen_US
dc.subject.otherRheumatoid arthritisen_US
dc.subject.otherCircadian variationsen_US
dc.subject.otherNeutrophilsen_US
dc.titleCircadian variations in the superoxide production, enzyme release and neutrophil aggregation in patients with rheumatoid arthritis and controlsen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1093/rheumatology/30.2.138en_US
dc.identifier.scopus0025752854-
dc.identifier.isiA1991FF10500016-
dcterms.isPartOfBritish Journal Of Rheumatology-
dcterms.sourceBritish Journal Of Rheumatology[ISSN 0263-7103],v. 30 (2), p. 138-140-
dc.contributor.authorscopusid7004285731-
dc.contributor.authorscopusid57197402008-
dc.contributor.authorscopusid16748082900-
dc.contributor.authorscopusid7006665953-
dc.contributor.authorscopusid7101622683-
dc.contributor.authorscopusid7003297397-
dc.description.lastpage140en_US
dc.identifier.issue2-
dc.description.firstpage138en_US
dc.relation.volume30en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:A1991FF10500016-
dc.contributor.daisngid828897-
dc.contributor.daisngid12582055-
dc.contributor.daisngid13245069-
dc.contributor.daisngid2324426-
dc.contributor.daisngid9491823-
dc.contributor.daisngid550893-
dc.description.notasContinues: British journal of rheumatology ISSN 0263-7103en_US
dc.identifier.investigatorRIDE-7910-2010-
dc.identifier.investigatorRIDNo ID-
dc.utils.revisionen_US
dc.identifier.ulpgces
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGrupo de investigaciones infecciosas, nutricionales e inflamatorias en pacientes hospitalarios / Study Group on infectious, nutritional and inflammatory diseases in hospitalized patients-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptCiencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-2013-6664-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameNaranjo Hernández, Antonio-
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