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Title: Adjustment in the clinical practice of treat-to-target guidelines for rheumatoid arthritis: Results of the ToARCan study
Authors: Naranjo, Antonio 
Cáceres, Laura
Hernández-Beriaín, José Ángel 
Francisco, Félix
Ojeda, Soledad
Talaverano, Sigrid
Nóvoa-Medina, Javier
Martín, José Adán
Delgado, Esmeralda
Trujillo, Elisa
Álvarez, Fátima
Magdalena, Laura
Rodríguez-Lozano, Carlos
UNESCO Clasification: 32 Ciencias médicas
320509 Reumatología
Keywords: Remission Induction Cohort
Issue Date: 2016
Journal: Reumatologia Clinica 
Abstract: Objective:To analyze compliance with t2t clinical practice guidelines.Methods:Cross-sectional observational study in consecutive patients with rheumatoid arthritis (RA) in 5 hospitals in the Canary Islands. Patients filled out activity scales, HAQ and answered the question of whether the doctor had explained the treatment target. The rheumatologist also collected: visits in the past year, use of activity indices and HAQ, DAS28 of current visit and date of the next visit. The percentage of compliance to indicators based on the t2t recommendations (R) 1, 3, 5-7 and 10 was analyzed.Results:A total of 343 patients were recruited, 77% female, mean age 57, RA duration of 10 years. Median visits in the last year were 3 and mean time between last and current visit was 5.6 months. A total of 93% of the patients were treated with DMARDs and 44% were in remission by DAS (R1). In the previous visit, documented joint count was present in 85%, a HAQ in 19%, patient VAS in 41%, and a DAS28 in 35% of the patients (R6). The next visit was scheduled at an average of 4.3 months (R5). In 64% of patients with DAS28> 3.2 a visit between one and 3 months was scheduled (R5). A total of 96% of patients said they had been informed of the treatment target (R10). Variability between centers existed but was moderate. The only factor determining the performance of a DAS28 in the last visit was the patient's center of origin.Conclusion:The Canary Island centers studied achieved high levels of remission and low activity in their patients. The performance of composite indices and follow-up frequency recommended by the t2t are met, although there is room for improvement.
ISSN: 1699-258X
DOI: 10.1016/j.reuma.2015.03.003
Source: Reumatologia Clinica[ISSN 1699-258X],v. 12, p. 34-38
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