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Title: Diet, a new target to prevent depression?
Authors: Sanchez-Villegas, Almudena 
Martínez-González, Miguel A.
UNESCO Clasification: 32 Ciencias médicas
3206 Ciencias de la nutrición
3211 Psiquiatría
Keywords: Neurotrophic Factor
Omega-3-Fatty-Acids, et al
Issue Date: 2013
Project: Papel de la Ingestión de Ácidos Grasos Omega-3 y de la Actividad Física en la Prevención de la Depresión 
Papel de la Dieta y la Actividad Física Sobre la Calidad de Vida y la Enfermedad Mental en El Estudio Sun 
Journal: BMC Medicine 
Abstract: Background: Research on the role of diet in the prevention of depression is scarce. Some evidence suggests that depression shares common mechanisms with cardiovascular disease.Discussion: Before considering the role of diet in the prevention of depression, several points need to be considered. First, in general, evidence has been found for the effects of isolated nutrients or foods, and not for dietary patterns. Second, most previous studies have a cross-sectional design. Third, information is generally collected though questionnaires, increasing the risk of misclassification bias. Fourth, adequate control of confounding factors in observational studies is mandatory.Summary: Only a few cohort studies have analyzed the relationship between overall dietary patterns, such as the Mediterranean diet, and primary prevention of depression. They have found similar results to those obtained for the role of this dietary pattern in cardiovascular disease. To confirm the findings obtained in these initial cohort studies, we need further observational longitudinal studies with improved methodology, as well as large randomized primary prevention trials, with interventions based on changes in the overall food pattern, that include participants at high risk of mental disorders. © 2013 Sanchez-Villegas and Martínez-González; licensee BioMed Central Ltd.
ISSN: 1741-7015
DOI: 10.1186/1741-7015-11-3
Source: Bmc Medicine [ISSN 1741-7015], v. 11(3) (Enero 2013)
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