Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/49005
Campo DC Valoridioma
dc.contributor.authorNieto García, A.en_US
dc.contributor.authorNevot Falcó, S.en_US
dc.contributor.authorCarrillo Díaz, T.en_US
dc.contributor.authorCumplido Bonny, J. Áen_US
dc.contributor.authorIzquierdo Calderón, J. P.en_US
dc.contributor.authorHernández-Peña, Jenaroen_US
dc.date.accessioned2018-11-24T03:03:53Z-
dc.date.available2018-11-24T03:03:53Z-
dc.date.issued2013en_US
dc.identifier.issn1764-1489en_US
dc.identifier.urihttp://hdl.handle.net/10553/49005-
dc.description.abstractIntroduction: Although the efficacy and safety of high dose hypoallergenic mite subcutaneous immunotherapy (SCIT) using a conventional administration schedule has already been demonstrated, there is no reported experience on the safety of these extracts with cluster schedules. We wanted to determine whether the use of a cluster schedule of a hypoallergenic allergen with a high concentration of house dust mite allergens commonly used in normal practice was safe and well-tolerated in patients with dust mite allergy. Material and methods: Multicentre, observational, retrospective study of dust mite allergic patients treated with a cluster schedule of SCIT (Acaroid; Day 1: 300/300 therapeutic units, TU--Day 8: 1000/1000 TU--Day 15: 3000/3000 TU) in 23 Spanish sites. Results: Cluster schedule was used on 434 patients (40.1% children), with a total of 3256 doses (38.2% in children). There were 88 clinically relevant adverse reactions, 79 out of them local and 9 systemic (but mild-moderate) that amounted to 2.7% of all the administered doses. All the patients fulfilled the cluster schedule. Conclusions: Cluster schedule with high dose hypoallergenic mite-SCIT was safe and well-tolerated in routine clinical practice. Therefore, its use could reduce the costs and time needed to achieve the desired maintenance dose and increase compliance.en_US
dc.languageengen_US
dc.relation.ispartofEuropean Annals of Allergy and Clinical Immunologyen_US
dc.sourceEuropean Annals of Allergy and Clinical Immunology[ISSN 1764-1489],v. 45, p. 78-83 (Mayo 2013)en_US
dc.subject32 Ciencias médicasen_US
dc.subject320710 Inmunopatologíaen_US
dc.subject320701 Alergiasen_US
dc.subject.otherHypersensitivityen_US
dc.subject.otherAntigensen_US
dc.subject.otherDermatophagoidesen_US
dc.subject.otherImmunotherapyen_US
dc.titleSafety of cluster specific immunotherapy with a modified high-dose house dust mite extracten_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.scopus84879730575-
dc.contributor.authorscopusid6603870787-
dc.contributor.authorscopusid6602208998-
dc.contributor.authorscopusid6602765567-
dc.contributor.authorscopusid55520909900-
dc.contributor.authorscopusid55668951500-
dc.contributor.authorscopusid6506129842-
dc.description.lastpage83en_US
dc.description.firstpage78en_US
dc.relation.volume45en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.numberofpages5en_US
dc.utils.revisionen_US
dc.date.coverdateMayo 2013en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr0,632-
dc.description.sjrqQ3-
dc.description.esciESCI-
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptGIR IUIBS: Patología médica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-3047-8908-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameCarrillo Díaz, Teresa-
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