Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/48701
Title: Additional information on the role of histopathology in diagnosing diabetic foot osteomyelitis
Authors: Aragón-Sánchez, J.
Lázaro-Martínez, J. L.
Cabrera-Galván, J. J. 
UNESCO Clasification: 32 Ciencias médicas
320714 Osteopatología
Keywords: Osteomyelitis
Diabetic foot
Issue Date: 2014
Journal: Diabetic Medicine 
Abstract: Bone biopsy with both microbiological and histopathological purposes has been established as a high-quality criterion for diagnosing osteomyelitis in the feet of patients with diabetes [1]. However, some controversies have been reported, making the interpretation of the results difficult. A group of authors reported that 29.1% of patients with positive cultures of bone specimens had no histopathological findings of osteomyelitis in one series of patients with diabetes undergoing surgery for foot infections. They also reported that 25% of patients with positive histology had negative cultures [2]. Other authors had also reported such controversies [3], even when advanced imaging was performed as a diagnostic tool [4]. Furthermore, the agreement between pathologists diagnosing osteomyelitis in the feet of patients with diabetes could be below the level of 'reference standard' [5]. Finally, little information exists about histopathology in cases of Charcot neuroarthropathy, and it is well known that the clinical and radiological differentiation between Charcot neuroarthropathy and osteomyelitis is sometimes difficult.
URI: http://hdl.handle.net/10553/48701
ISSN: 0742-3071
DOI: 10.1111/dme.12283
Source: Diabetic Medicine[ISSN 0742-3071],v. 31, p. 113-116 (Enero 2014)
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