Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/48519
DC FieldValueLanguage
dc.contributor.authorNaredo, Esperanzaen_US
dc.contributor.authorMartín Rodríguez, Manuel Maríaen_US
dc.contributor.authorCampos, Cristinaen_US
dc.contributor.authorRodríguez-Heredia, José Manuelen_US
dc.contributor.authorMedina, Julio A.en_US
dc.contributor.authorGiner, Emilioen_US
dc.contributor.authorMartínez, Olgaen_US
dc.contributor.authorToyos, Francisco Javieren_US
dc.contributor.authorRuíz, Teresaen_US
dc.contributor.authorRos, Inmaculadaen_US
dc.contributor.authorPujol, Manuelen_US
dc.contributor.authorMiquel, Xavieren_US
dc.contributor.authorAznar, Juan Joséen_US
dc.contributor.authorChamizo, Eugenioen_US
dc.contributor.authorPáez, Manuelen_US
dc.contributor.authorGarcía Morales, Pilaren_US
dc.contributor.authorRueda, Amaliaen_US
dc.contributor.authorTuneu, Roseren_US
dc.contributor.authorCorominas, Hectoren_US
dc.contributor.authorDe Agustín, Juan Joséen_US
dc.contributor.authorMoragues, Carmenen_US
dc.contributor.authorMínguez, Doloresen_US
dc.contributor.authorWillisch, Alfredoen_US
dc.contributor.authorGonzález Cruz, Isabelen_US
dc.contributor.authorAragón, Angelen_US
dc.contributor.authorIglesias, Gerardoen_US
dc.contributor.authorArmas, Carlosen_US
dc.contributor.authorValdazo, Juan Pabloen_US
dc.contributor.authorVargas, Carmenen_US
dc.contributor.authorCalvo-Alén, Jaimeen_US
dc.contributor.authorJuan-Mas, Antonioen_US
dc.contributor.authorSalvador, Georginaen_US
dc.contributor.authorPuigdollers, Angelsen_US
dc.contributor.authorGalíndez, Evaen_US
dc.contributor.authorGarrido, Noemien_US
dc.contributor.authorSalaberri, Joséen_US
dc.contributor.authorRaya, Enriqueen_US
dc.contributor.authorSalles, Meritxellen_US
dc.contributor.authorDíaz, Césaren_US
dc.contributor.authorCuadra, José Luisen_US
dc.contributor.authorGarrido, Jesúsen_US
dc.date.accessioned2018-11-23T22:31:09Z-
dc.date.available2018-11-23T22:31:09Z-
dc.date.issued2008en_US
dc.identifier.issn2151-4658en_US
dc.identifier.urihttp://hdl.handle.net/10553/48519-
dc.description.abstractObjective To investigate the validity, reproducibility, and responsiveness of a simplified power Doppler ultrasound (PDUS) assessment of joint inflammation compared with a comprehensive 44-joint PDUS assessment in patients with rheumatoid arthritis (RA) who started therapy with a biologic agent. Methods A total of 160 patients with active RA who started a biologic agent were prospectively recruited in 18 Spanish centers. The patients underwent clinical and laboratory assessment and blinded PDUS examination at baseline and 6 months. A PDUS examination of 128 synovial sites in 44 joints was performed. US synovitis and PD signal were semiquantitatively graded from 1 to 3 in all synovial sites. US count and index for synovitis and PD signal were obtained. PDUS intraobserver and interobserver reliability were evaluated. A process of data reduction based on the frequency of involvement of synovial sites by both synovitis and PD signal was conducted. Construct and discriminant validity of a simplified PDUS assessment was investigated. Results A PDUS simplified assessment including 24 synovial sites from 12 joints detected 100% of patients with synovitis and 91% of patients with PD signal. There was a highly significant correlation between the 44-joint count and index for synovitis and PD signal and the 12-joint count and index for synovitis and PD signal at baseline and 6 months (r = 0.84–0.90, P < 0.0005). The smallest detectable difference was lower than the mean change in simplified PDUS variables. Conclusion A 12-joint PDUS assessment of RA joint inflammation may be a valid, feasible method for multicenter monitoring of therapeutic response to biologic agents.en_US
dc.languageengen_US
dc.relation.ispartofArthritis Care and Researchen_US
dc.sourceArthritis Care and Research [ISSN 2151-4658], v. 59 (4), p. 515-522, (Abril 2008)en_US
dc.subject32 Ciencias médicasen_US
dc.titleValidity, reproducibility, and responsiveness of a twelve-joint simplified power Doppler ultrasonographic assessment of joint inflammation in rheumatoid arthritisen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1002/art.23529en_US
dc.identifier.scopus42449113822-
dc.contributor.authorscopusid6602827091-
dc.contributor.authorscopusid57197402008-
dc.contributor.authorscopusid7102969057-
dc.contributor.authorscopusid6506094465-
dc.contributor.authorscopusid7402369497-
dc.contributor.authorscopusid24075743200-
dc.contributor.authorscopusid55484869300-
dc.contributor.authorscopusid24077397500-
dc.contributor.authorscopusid35488639700-
dc.contributor.authorscopusid6602869088-
dc.contributor.authorscopusid55438598600-
dc.contributor.authorscopusid24076830800-
dc.contributor.authorscopusid7402429140-
dc.contributor.authorscopusid7103230096-
dc.contributor.authorscopusid6505707909-
dc.contributor.authorscopusid21641843400-
dc.contributor.authorscopusid56259798700-
dc.contributor.authorscopusid56844903200-
dc.contributor.authorscopusid24077681300-
dc.contributor.authorscopusid6602373022-
dc.contributor.authorscopusid10043921600-
dc.contributor.authorscopusid10044748700-
dc.contributor.authorscopusid56712991300-
dc.contributor.authorscopusid6506237643-
dc.contributor.authorscopusid6507737746-
dc.contributor.authorscopusid7006292946-
dc.contributor.authorscopusid7003702316-
dc.contributor.authorscopusid24075588500-
dc.contributor.authorscopusid16200352900-
dc.contributor.authorscopusid7101622683-
dc.contributor.authorscopusid6603550211-
dc.contributor.authorscopusid6506219654-
dc.contributor.authorscopusid7003510663-
dc.contributor.authorscopusid24076948900-
dc.contributor.authorscopusid6603844651-
dc.contributor.authorscopusid24075806500-
dc.contributor.authorscopusid56334262900-
dc.contributor.authorscopusid6507707300-
dc.contributor.authorscopusid7006638353-
dc.contributor.authorscopusid7202447355-
dc.contributor.authorscopusid57090247000-
dc.contributor.authorscopusid7202779769-
dc.description.lastpage522en_US
dc.description.firstpage515en_US
dc.relation.volume59en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.utils.revisionen_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR Estudios sobre humanismo, filología y pervivencia clásicas y literatura canaria-
crisitem.author.deptGIR Estudios sociolingüísticos y socioculturales-
crisitem.author.deptDepartamento de Filología Moderna, Traducción e Interpretación-
crisitem.author.orcid0000-0002-6815-2743-
crisitem.author.parentorgDepartamento de Filología Hispánica Clásica y de Estudios Árabes y Orientales-
crisitem.author.parentorgDepartamento de Filología Moderna, Traducción e Interpretación-
crisitem.author.fullNameMartín Rodríguez,Manuel María-
crisitem.author.fullNameGarcía Morales, Pilar-
crisitem.author.fullNameGonzález Cruz, María Isabel-
Appears in Collections:Artículos
Show simple item record

SCOPUSTM   
Citations

247
checked on Dec 1, 2024

WEB OF SCIENCETM
Citations

252
checked on Nov 24, 2024

Page view(s)

76
checked on Sep 23, 2023

Google ScholarTM

Check

Altmetric


Share



Export metadata



Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.