Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/48519
DC Field | Value | Language |
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dc.contributor.author | Naredo, Esperanza | en_US |
dc.contributor.author | Martín Rodríguez, Manuel María | en_US |
dc.contributor.author | Campos, Cristina | en_US |
dc.contributor.author | Rodríguez-Heredia, José Manuel | en_US |
dc.contributor.author | Medina, Julio A. | en_US |
dc.contributor.author | Giner, Emilio | en_US |
dc.contributor.author | Martínez, Olga | en_US |
dc.contributor.author | Toyos, Francisco Javier | en_US |
dc.contributor.author | Ruíz, Teresa | en_US |
dc.contributor.author | Ros, Inmaculada | en_US |
dc.contributor.author | Pujol, Manuel | en_US |
dc.contributor.author | Miquel, Xavier | en_US |
dc.contributor.author | Aznar, Juan José | en_US |
dc.contributor.author | Chamizo, Eugenio | en_US |
dc.contributor.author | Páez, Manuel | en_US |
dc.contributor.author | García Morales, Pilar | en_US |
dc.contributor.author | Rueda, Amalia | en_US |
dc.contributor.author | Tuneu, Roser | en_US |
dc.contributor.author | Corominas, Hector | en_US |
dc.contributor.author | De Agustín, Juan José | en_US |
dc.contributor.author | Moragues, Carmen | en_US |
dc.contributor.author | Mínguez, Dolores | en_US |
dc.contributor.author | Willisch, Alfredo | en_US |
dc.contributor.author | González Cruz, Isabel | en_US |
dc.contributor.author | Aragón, Angel | en_US |
dc.contributor.author | Iglesias, Gerardo | en_US |
dc.contributor.author | Armas, Carlos | en_US |
dc.contributor.author | Valdazo, Juan Pablo | en_US |
dc.contributor.author | Vargas, Carmen | en_US |
dc.contributor.author | Calvo-Alén, Jaime | en_US |
dc.contributor.author | Juan-Mas, Antonio | en_US |
dc.contributor.author | Salvador, Georgina | en_US |
dc.contributor.author | Puigdollers, Angels | en_US |
dc.contributor.author | Galíndez, Eva | en_US |
dc.contributor.author | Garrido, Noemi | en_US |
dc.contributor.author | Salaberri, José | en_US |
dc.contributor.author | Raya, Enrique | en_US |
dc.contributor.author | Salles, Meritxell | en_US |
dc.contributor.author | Díaz, César | en_US |
dc.contributor.author | Cuadra, José Luis | en_US |
dc.contributor.author | Garrido, Jesús | en_US |
dc.date.accessioned | 2018-11-23T22:31:09Z | - |
dc.date.available | 2018-11-23T22:31:09Z | - |
dc.date.issued | 2008 | en_US |
dc.identifier.issn | 2151-4658 | en_US |
dc.identifier.uri | http://hdl.handle.net/10553/48519 | - |
dc.description.abstract | Objective To investigate the validity, reproducibility, and responsiveness of a simplified power Doppler ultrasound (PDUS) assessment of joint inflammation compared with a comprehensive 44-joint PDUS assessment in patients with rheumatoid arthritis (RA) who started therapy with a biologic agent. Methods A total of 160 patients with active RA who started a biologic agent were prospectively recruited in 18 Spanish centers. The patients underwent clinical and laboratory assessment and blinded PDUS examination at baseline and 6 months. A PDUS examination of 128 synovial sites in 44 joints was performed. US synovitis and PD signal were semiquantitatively graded from 1 to 3 in all synovial sites. US count and index for synovitis and PD signal were obtained. PDUS intraobserver and interobserver reliability were evaluated. A process of data reduction based on the frequency of involvement of synovial sites by both synovitis and PD signal was conducted. Construct and discriminant validity of a simplified PDUS assessment was investigated. Results A PDUS simplified assessment including 24 synovial sites from 12 joints detected 100% of patients with synovitis and 91% of patients with PD signal. There was a highly significant correlation between the 44-joint count and index for synovitis and PD signal and the 12-joint count and index for synovitis and PD signal at baseline and 6 months (r = 0.84–0.90, P < 0.0005). The smallest detectable difference was lower than the mean change in simplified PDUS variables. Conclusion A 12-joint PDUS assessment of RA joint inflammation may be a valid, feasible method for multicenter monitoring of therapeutic response to biologic agents. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Arthritis Care and Research | en_US |
dc.source | Arthritis Care and Research [ISSN 2151-4658], v. 59 (4), p. 515-522, (Abril 2008) | en_US |
dc.subject | 32 Ciencias médicas | en_US |
dc.title | Validity, reproducibility, and responsiveness of a twelve-joint simplified power Doppler ultrasonographic assessment of joint inflammation in rheumatoid arthritis | en_US |
dc.type | info:eu-repo/semantics/article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1002/art.23529 | en_US |
dc.identifier.scopus | 42449113822 | - |
dc.contributor.authorscopusid | 6602827091 | - |
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dc.contributor.authorscopusid | 7006638353 | - |
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dc.contributor.authorscopusid | 57090247000 | - |
dc.contributor.authorscopusid | 7202779769 | - |
dc.description.lastpage | 522 | en_US |
dc.description.firstpage | 515 | en_US |
dc.relation.volume | 59 | en_US |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.utils.revision | Sí | en_US |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-MED | en_US |
item.grantfulltext | none | - |
item.fulltext | Sin texto completo | - |
crisitem.author.dept | GIR Estudios sobre humanismo, filología y pervivencia clásicas y literatura canaria | - |
crisitem.author.dept | GIR Estudios sociolingüísticos y socioculturales | - |
crisitem.author.dept | Departamento de Filología Moderna, Traducción e Interpretación | - |
crisitem.author.orcid | 0000-0002-6815-2743 | - |
crisitem.author.parentorg | Departamento de Filología Hispánica Clásica y de Estudios Árabes y Orientales | - |
crisitem.author.parentorg | Departamento de Filología Moderna, Traducción e Interpretación | - |
crisitem.author.fullName | Martín Rodríguez,Manuel María | - |
crisitem.author.fullName | García Morales, Pilar | - |
crisitem.author.fullName | González Cruz, María Isabel | - |
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