Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/47517
DC FieldValueLanguage
dc.contributor.authorSierra Pulpillo, Eva Maríaen_US
dc.contributor.authorFernández Rodríguez, Antonio Jesúsen_US
dc.contributor.authorEspinosa De Los Monteros Y Zayas, Antonioen_US
dc.contributor.authorJáber Mohamad, José Raduánen_US
dc.contributor.authorAndrada Borzollino, Marisa Anaen_US
dc.contributor.authorHerráez Thomas, Pedro Manuelen_US
dc.contributor.otherFernandez, Antonio-
dc.contributor.otherSierra, Eva-
dc.date.accessioned2018-11-23T14:11:33Z-
dc.date.available2018-11-23T14:11:33Z-
dc.date.issued2012en_US
dc.identifier.issn1090-0233en_US
dc.identifier.urihttp://hdl.handle.net/10553/47517-
dc.description.abstractSkeletal muscle samples were examined post-mortem in 148 cetaceans over a 12-year period. Histological analysis included haematoxylin and eosin (HE) and periodic acid-Schiff (PAS) staining with and without diastase digestion. In addition, histological muscle sections were immunostained for ubiquitin and fast and slow heavy-chain myosin isoforms.PAS-positive, diastase-resistant inclusions were detected in 26 animals from 11 different species. Older cetaceans were preferentially affected. These intrafibre inclusions varied from large aggregates to multiple coarse granules and were typically associated with type II fibres. All diastase-resistant inclusions were positive for ubiquitin. These features resembled those inclusions described as complex polysaccharide in horses. Based on these histological findings and the ubiquitin staining pattern, a morphological diagnosis of complex polysaccharide storage myopathy is proposed.en_US
dc.languageengen_US
dc.publisher1090-0233
dc.relation.ispartofVeterinary Journalen_US
dc.sourceThe Veterinary Journal [ISSN 1090-0233], v. 193 (1), p. 152-156en_US
dc.subject240110 Histología animalen_US
dc.subject240118 Mamíferosen_US
dc.subject.otherGlycogen-Storage-Diseaseen_US
dc.subject.otherExertional Rhabdomyolysisen_US
dc.subject.otherMyopathyen_US
dc.subject.otherMutationen_US
dc.subject.otherNecropsyen_US
dc.subject.otherComplex polysaccharideen_US
dc.subject.otherSkeletal muscleen_US
dc.subject.otherCetaceansen_US
dc.subject.otherHistopathologyen_US
dc.subject.otherImmunohistochemistryen_US
dc.titleComplex polysaccharide inclusions in the skeletal muscle of stranded cetaceansen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.tvjl.2011.09.021en_US
dc.identifier.scopus84863781014-
dc.identifier.isi000307478200029-
dcterms.isPartOfVeterinary Journal
dcterms.sourceVeterinary Journal[ISSN 1090-0233],v. 193 (1), p. 152-156
dc.contributor.authorscopusid15742962600-
dc.contributor.authorscopusid56673009900-
dc.contributor.authorscopusid36928058400-
dc.contributor.authorscopusid7004667021-
dc.contributor.authorscopusid6602991535-
dc.contributor.authorscopusid57194503614-
dc.description.lastpage156en_US
dc.description.firstpage152en_US
dc.relation.volume193en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000307478200029-
dc.contributor.daisngid30396242-
dc.contributor.daisngid454532-
dc.contributor.daisngid176520-
dc.contributor.daisngid700159-
dc.contributor.daisngid959492-
dc.contributor.daisngid862879-
dc.contributor.daisngid30335206-
dc.contributor.daisngid523902-
dc.identifier.investigatorRIDG-3448-2015-
dc.identifier.investigatorRIDH-9352-2015-
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Sierra, E-
dc.contributor.wosstandardWOS:Fernandez, A-
dc.contributor.wosstandardWOS:de los Monteros, AE-
dc.contributor.wosstandardWOS:Jaber, JR-
dc.contributor.wosstandardWOS:Andrada, M-
dc.contributor.wosstandardWOS:Herraez, P-
dc.date.coverdateJulio 2012en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-VETen_US
dc.description.sjr1,041
dc.description.jcr2,424
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptMorfología-
crisitem.author.deptHistología y Patología Veterinaria-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptMorfología-
crisitem.author.deptHistología y Patología Veterinaria-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptMorfología-
crisitem.author.deptMorfología-
crisitem.author.deptHistología y Patología Veterinaria-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptMorfología-
crisitem.author.deptHistología y Patología Veterinaria-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptMorfología-
crisitem.author.orcid0000-0003-3749-8845-
crisitem.author.orcid0000-0001-5281-0521-
crisitem.author.orcid0000-0002-7736-3139-
crisitem.author.orcid0000-0001-6116-7275-
crisitem.author.orcid0000-0002-2411-9714-
crisitem.author.orcid0000-0001-9316-2882-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.fullNameSierra Pulpillo, Eva María-
crisitem.author.fullNameFernández Rodríguez, Antonio Jesús-
crisitem.author.fullNameEspinosa De Los Monteros Y Zayas, Antonio-
crisitem.author.fullNameJáber Mohamad, José Raduán-
crisitem.author.fullNameAndrada Borzollino, Marisa Ana-
crisitem.author.fullNameHerráez Thomas, Pedro Manuel-
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