Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/47397
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dc.contributor.authorVilar Guereño, José Manuelen_US
dc.contributor.authorMorales Doreste, Manuel Franciscoen_US
dc.contributor.authorSantana Del Pino, Ángeloen_US
dc.contributor.authorBatista Arteaga, Miguelen_US
dc.contributor.authorMiró Rodríguez, Franciscoen_US
dc.contributor.authorSpinella, Giuseppeen_US
dc.date.accessioned2018-11-23T13:14:34Z-
dc.date.available2018-11-23T13:14:34Z-
dc.date.issued2013en_US
dc.identifier.issn0253-8318en_US
dc.identifier.urihttp://hdl.handle.net/10553/47397-
dc.description.abstractThe aim of this study was to assess the efficacy of mavacoxib, a cox-2 inhibitor, to improve the peak vertical force (PVF) and vertical impulse (VI) of lame client-owned dogs with severe coxofemoral osteoarthrosis (OA) by using a force platform. A group of ten canarian presa dogs with lameness and pain for a severe osteoarthrosis due to hip dysplasia were used for this study. Five additional sound dogs of the same breed were used as control groups. A single force platform used to register vertical forces was mounted in a 7 m runway. Mean (+/- SD) values for speed of dogs were 1.6 +/- 0.5 m/s. Data corresponding with 5 valid trials were recorded at walk at day 0, 7, 60 and 180 after starting treatment procedure. The dosing regimen consisted of a loading oral dose of 2 mg/kg to be repeated after 14 days, thereafter the dosing interval was 1 month. OA dogs showed a significant improvement of PVF after two months of about 7% bm in the force exerted by diseased limbs and a significant VI improvement after two months of about 1.6% bm in the VI exerted by diseased limbs. This study clearly showed that dogs treated with mavacoxib increased PVF over time, as soon as seven days after medical therapy, demonstrating a high potential for clinical use in the treatment of lameness associated with OA of hip joint.en_US
dc.languageengen_US
dc.publisher0253-8318-
dc.relation.ispartofPakistan Veterinary Journalen_US
dc.sourcePakistan Veterinary Journal [ISSN 0253-8318], v. 33 (2), p. 229-233en_US
dc.subject240111 Patología animalen_US
dc.subject310907 Patologíaen_US
dc.subject.otherDogen_US
dc.subject.otherForce platformen_US
dc.subject.otherLamenessen_US
dc.subject.otherMavacoxiben_US
dc.subject.otherOsteoarthrosisen_US
dc.subject.otherCanarian presa dogsen_US
dc.subject.otherHip dysplasiaen_US
dc.subject.otherPeak vertical force (PVF)en_US
dc.subject.otherCoxofemoral osteoarthrosisen_US
dc.titleLong-term valuation of oral mavacoxib in osteoarthrosic dogs using force platform analysisen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.scopus84876150651-
dc.identifier.isi000316941100022-
dc.contributor.authorscopusid7005533720-
dc.contributor.authorscopusid7202590467-
dc.contributor.authorscopusid56554207500-
dc.contributor.authorscopusid7005481929-
dc.contributor.authorscopusid57212844863-
dc.contributor.authorscopusid7003518319-
dc.contributor.authorscopusid6602842395-
dc.description.lastpage233en_US
dc.description.firstpage229en_US
dc.relation.volume33en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid913655-
dc.contributor.daisngid5599472-
dc.contributor.daisngid4213964-
dc.contributor.daisngid3097430-
dc.contributor.daisngid1506763-
dc.contributor.daisngid1106016-
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Vilar, JM-
dc.contributor.wosstandardWOS:Morales, M-
dc.contributor.wosstandardWOS:Santana, A-
dc.contributor.wosstandardWOS:Batista, M-
dc.contributor.wosstandardWOS:Miro, F-
dc.contributor.wosstandardWOS:Spinella, G-
dc.date.coverdateAbril 2013en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-VETen_US
dc.description.sjr0,516
dc.description.jcr1,392
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.fulltextCon texto completo-
item.grantfulltextopen-
crisitem.author.deptGIR IUIBS: Medicina Veterinaria e Investigación Terapéutica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR Anatomía Aplicada y Herpetopatología-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR Estadística-
crisitem.author.deptDepartamento de Matemáticas-
crisitem.author.deptGIR IUIBS: Medicina Veterinaria e Investigación Terapéutica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.orcid0000-0002-2060-2274-
crisitem.author.orcid0000-0002-1436-8899-
crisitem.author.orcid0000-0002-6513-4814-
crisitem.author.orcid0000-0001-9753-4786-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgDepartamento de Morfología-
crisitem.author.parentorgDepartamento de Matemáticas-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameVilar Guereño, José Manuel-
crisitem.author.fullNameMorales Doreste, Manuel Francisco-
crisitem.author.fullNameSantana Del Pino, Ángelo-
crisitem.author.fullNameBatista Arteaga, Miguel-
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