Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/47395
DC FieldValueLanguage
dc.contributor.authorVilar Guereño, José Manuelen_US
dc.contributor.authorBatista Arteaga, Miguelen_US
dc.contributor.authorMorales Doreste, Manuel Franciscoen_US
dc.contributor.authorSantana Del Pino, Ángeloen_US
dc.contributor.authorCuervo Serrato, Belénen_US
dc.contributor.authorRubio Zaragoza, Mónicaen_US
dc.contributor.authorCugat Bertomeu, Ramónen_US
dc.contributor.authorSopena Juncosa, Joaquínen_US
dc.contributor.authorCarrillo Poveda, José Maríaen_US
dc.date.accessioned2018-11-23T13:13:36Z-
dc.date.available2018-11-23T13:13:36Z-
dc.date.issued2014en_US
dc.identifier.issn1746-6148en_US
dc.identifier.otherWoS-
dc.identifier.urihttp://hdl.handle.net/10553/47395-
dc.description.abstractBackground Regenerative medicine using Mesenchymal Stem Cells (MSC) alone or combined with Plasma Rich in Growth Factors (PRGF) is a rapidly growing area of clinical research and is currently also being used to treat osteoarthritis (OA). Force platform analysis has been consistently used to verify and quantify the efficacy of different therapeutic strategies for the treatment of OA in dogs including MSC associated to PRGF, but never with AD-MSC alone. The aim of this study was to use a force platform to measure the efficacy of intraarticular ADMSC administration for limb function improvement in dogs with severe OA. Results Ten lame dogs with severe hip OA and a control group of 5 sound dogs were used for this study. Results were statistically analyzed to detect a significant increase in peak vertical force (PVF) and vertical impulse (VI) in treated dogs. Mean values of PVF and VI were significantly improved within the first three months post-treatment in the OA group, increasing 9% and 2.5% body weight, respectively, at day 30. After this, the effect seems to decrease reaching initial values. Conclusion Intraarticular ADMSC therapy objectively improved limb function in dogs with hip OA. The duration of maximal effect was less than 3 months.en_US
dc.languageengen_US
dc.relation.ispartofBMC Veterinary Researchen_US
dc.sourceBMC Veterinary Research [ISSN 1746-6148], v. 10 (1), 143en_US
dc.subject240111 Patología animalen_US
dc.subject310907 Patologíaen_US
dc.subject.otherOsteoarthrosisen_US
dc.subject.otherHipen_US
dc.subject.otherAdipose-derived mesenchymal stem cellsen_US
dc.subject.otherMSCen_US
dc.subject.otherForce platformen_US
dc.subject.otherDogsen_US
dc.subject.otherMesenchymal Stem Cellsen_US
dc.subject.otherPlasma Rich in Growth Factorsen_US
dc.subject.otherPRGFen_US
dc.subject.otherOsteoarthritisen_US
dc.subject.otherOAen_US
dc.titleAssessment of the effect of intraarticular injection of autologous adipose-derived mesenchymal stem cells in osteoarthritic dogs using a double blinded force platform analysisen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1186/1746-6148-10-143en_US
dc.identifier.scopus84922480296-
dc.identifier.isi000338590200001-
dc.contributor.authorscopusid7005533720-
dc.contributor.authorscopusid7005481929-
dc.contributor.authorscopusid7202590467-
dc.contributor.authorscopusid56554207500-
dc.contributor.authorscopusid57194687048-
dc.contributor.authorscopusid9532488300-
dc.contributor.authorscopusid21233262500-
dc.contributor.authorscopusid9534772600-
dc.contributor.authorscopusid37071989800-
dc.identifier.eissn1746-6148-
dc.identifier.issue143-
dc.relation.volume10en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid913655-
dc.contributor.daisngid3097430-
dc.contributor.daisngid12043575-
dc.contributor.daisngid2332689-
dc.contributor.daisngid7071963-
dc.contributor.daisngid1882833-
dc.contributor.daisngid608093-
dc.contributor.daisngid2284901-
dc.contributor.daisngid30324417-
dc.description.numberofpages7en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Vilar, JM-
dc.contributor.wosstandardWOS:Batista, M-
dc.contributor.wosstandardWOS:Morales, M-
dc.contributor.wosstandardWOS:Santana, A-
dc.contributor.wosstandardWOS:Cuervo, B-
dc.contributor.wosstandardWOS:Rubio, M-
dc.contributor.wosstandardWOS:Cugat, R-
dc.contributor.wosstandardWOS:Sopena, J-
dc.contributor.wosstandardWOS:Carrillo, JM-
dc.date.coverdateJulio 2014en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-VETen_US
dc.description.sjr0,885
dc.description.jcr1,777
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Medicina Veterinaria e Investigación Terapéutica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR IUIBS: Medicina Veterinaria e Investigación Terapéutica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR Anatomía Aplicada y Herpetopatología-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR Estadística-
crisitem.author.deptDepartamento de Matemáticas-
crisitem.author.orcid0000-0002-2060-2274-
crisitem.author.orcid0000-0001-9753-4786-
crisitem.author.orcid0000-0002-1436-8899-
crisitem.author.orcid0000-0002-6513-4814-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgDepartamento de Morfología-
crisitem.author.parentorgDepartamento de Matemáticas-
crisitem.author.fullNameVilar Guereño, José Manuel-
crisitem.author.fullNameBatista Arteaga, Miguel-
crisitem.author.fullNameMorales Doreste, Manuel Francisco-
crisitem.author.fullNameSantana Del Pino, Ángelo-
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