Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/47390
DC FieldValueLanguage
dc.contributor.authorQuintana-Hernández, Domingo J.en_US
dc.contributor.authorMiró-Barrachina, Maria T.en_US
dc.contributor.authorIbáñez-Fernández, Ignacio J.en_US
dc.contributor.authorSantana-Del Pino, Angeloen_US
dc.contributor.authorQuintana-Montesdeoca, Maria P.en_US
dc.contributor.authorRodríguez-De Vera, Bienvenidaen_US
dc.contributor.authorMorales-Casanova, Daviden_US
dc.contributor.authorDel Carmen Pérez-Vieitez, Mariaen_US
dc.contributor.authorRodríguez-García, Javieren_US
dc.contributor.authorBravo-Caraduje, Noeliaen_US
dc.date.accessioned2018-11-23T13:11:15Z-
dc.date.available2018-11-23T13:11:15Z-
dc.date.issued2015en_US
dc.identifier.issn1387-2877en_US
dc.identifier.otherWoS-
dc.identifier.urihttp://hdl.handle.net/10553/47390-
dc.description.abstractBackground: The Canary Islands longitudinal study on non-pharmacological treatments showed the overall effectiveness of mindfulness in Alzheimer's disease (AD). However, no specific data on the maintenance of cognitive capacities were presented.Objective: To determine whether the practice of mindfulness modifies the course of cognitive impairment in AD.Methods: Design: Longitudinal, non-inferiority and equivalence, randomized clinical trial, repeated-measures design, with three experimental groups and one control group. Participants: Patients with AD who voluntarily attended the Lidia Garcia Foundation (n = 502). Only those who were treated with donepezil and MMSE >= 18 were included (n = 120). Intervention: Over a two-year period, each group carried out three weekly sessions of stimulation based on mindfulness, cognitive stimulation therapy, and progressive muscle relaxation. Measures: Cognitive assessment CAMDEX-R (MMSE and CAMCOG). Statistical analysis: Repeated-measures ANOVA (p < 0.05) and the effect size Cohen's d were performed.Results: The mindfulness group showed significant scores compared with the control and muscle relaxation groups (p < 0.05), while mindfulness and cognitive stimulation therapy were equivalent (p >= 0.05). Group cognitive stimulation evolved better than the control (p < 0.05) group but not better than the muscle relaxation group (p >= 0.05). The effect size compared over two years was large for the mindfulness group (p >= 0.80), moderate for the relaxation group (p >= 0.50), and low for the cognitive stimulation group (p >= 0.20).Conclusion: The practice of mindfulness maintained cognitive function over a period of two years. This longitudinal study suggests that mindfulness can be used as a non-pharmacological treatment to slow cognitive impairment in AD.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Alzheimer's Diseaseen_US
dc.sourceJournal of Alzheimer's Disease [ISSN 1387-2877], v. 50, p. 217-232en_US
dc.subject32 Ciencias médicasen_US
dc.subject240401 Bioestadísticaen_US
dc.subject120903 Análisis de datosen_US
dc.subject.otherProgressive Muscle-Relaxationen_US
dc.subject.otherDefault-Mode Networken_US
dc.subject.otherStimulation Therapyen_US
dc.subject.otherStress Reductionen_US
dc.subject.otherOlder-Adultsen_US
dc.subject.otherImpairmenten_US
dc.subject.otherMeditationen_US
dc.subject.otherMemantineen_US
dc.subject.otherDonepezilen_US
dc.subject.otherRivastigmineen_US
dc.subject.otherAlzheimer'S Diseaseen_US
dc.subject.otherCognitive Impairmenten_US
dc.subject.otherCognitive Stimulation Therapyen_US
dc.subject.otherMindfulnessen_US
dc.subject.otherNon-Pharmacological Treatmentsen_US
dc.subject.otherProgressive Muscle Relaxationen_US
dc.titleMindfulness in the maintenance of cognitive capacities in Alzheimer's disease: a randomized clinical trialen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3233/JAD-143009en_US
dc.identifier.scopus84954091440-
dc.identifier.isi000368085200021-
dc.contributor.authorscopusid56173672400-
dc.contributor.authorscopusid56174248500-
dc.contributor.authorscopusid55240227500-
dc.contributor.authorscopusid56554207500-
dc.contributor.authorscopusid57053477400-
dc.contributor.authorscopusid6506336146-
dc.contributor.authorscopusid57053356300-
dc.contributor.authorscopusid57053565200-
dc.contributor.authorscopusid56553861000-
dc.contributor.authorscopusid57053514700-
dc.identifier.eissn1875-8908-
dc.description.lastpage232en_US
dc.identifier.issue1-
dc.description.firstpage217en_US
dc.relation.volume50en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid23763021-
dc.contributor.daisngid22584676-
dc.contributor.daisngid995762-
dc.contributor.daisngid2332689-
dc.contributor.daisngid34955273-
dc.contributor.daisngid31443022-
dc.contributor.daisngid16360742-
dc.contributor.daisngid4244887-
dc.contributor.daisngid5365471-
dc.contributor.daisngid25088731-
dc.description.numberofpages16en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Quintana-Hernandez, DJ-
dc.contributor.wosstandardWOS:Miro-Barrachina, MT-
dc.contributor.wosstandardWOS:Ibanez-Fernandez, IJ-
dc.contributor.wosstandardWOS:Santana-del Pino, A-
dc.contributor.wosstandardWOS:Quintana-Montesdeoca, MP-
dc.contributor.wosstandardWOS:Rodriguez-de Vera, B-
dc.contributor.wosstandardWOS:Morales-Casanova, D-
dc.contributor.wosstandardWOS:del Carmen Perez-Vieitez, M-
dc.contributor.wosstandardWOS:Rodriguez-Garcia, J-
dc.contributor.wosstandardWOS:Bravo-Caraduje, N-
dc.date.coverdateEnero 2016en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr1,812
dc.description.jcr3,92
dc.description.sjrqQ1
dc.description.jcrqQ2
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptEstadística-
crisitem.author.deptMatemáticas-
crisitem.author.orcid0000-0002-6513-4814-
crisitem.author.parentorgMatemáticas-
crisitem.author.fullNameSantana Del Pino, Ángelo-
crisitem.author.fullNameRodríguez de Vera, Bienvenida del C.-
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