Identificador persistente para citar o vincular este elemento:
http://hdl.handle.net/10553/46995
Campo DC | Valor | idioma |
---|---|---|
dc.contributor.author | Torres-Galván, M. | en_US |
dc.contributor.author | Quiralte, J. | en_US |
dc.contributor.author | Pestano, J. J. | en_US |
dc.contributor.author | Ortega, N. | en_US |
dc.contributor.author | Blanco, C. | en_US |
dc.contributor.author | Castillo, R. | en_US |
dc.contributor.author | Carrillo, T. | en_US |
dc.contributor.author | Pérez-Aciego, P. | en_US |
dc.contributor.author | Sánchez-García, F. | en_US |
dc.contributor.other | IBIS, ALERGICAS | - |
dc.contributor.other | Blanco, Carlos | - |
dc.contributor.other | Pestano Brito, Jose Juan | - |
dc.date.accessioned | 2018-11-23T10:00:55Z | - |
dc.date.available | 2018-11-23T10:00:55Z | - |
dc.date.issued | 2001 | en_US |
dc.identifier.issn | 0105-4538 | en_US |
dc.identifier.uri | http://hdl.handle.net/10553/46995 | - |
dc.description.abstract | Background: Rhinoconjunctivitis and bronchial asthma are atopic diseases with a high prevalence in the Canary Islands (Spain). Given that the most prevalent allergen is the house-dust mite Dermatophagoides pteronyssinus, early detection of genetically susceptible subjects would allow the application of preventive measures. The objective was to investigate the possible association of IL4-R1 (chromosome 5q31-q33) and Fc epsilon RI-beta ca (chromosome 11q13) markers with the atopic disease in our population.Methods: We performed a case/control study in which patients were recruited on the basis of diagnosis of rhinoconjunctivitis and/or bronchial asthma, and positive skin prick test to D. pteronyssinus. Analysis of IL4-R1 and Fc epsilon RI-beta ca microsatellites was carried out by PCR and electrophoresis in acrylamide gels.Results: We have not found evidence of association between IL4-R1 and Fc epsilon RI-beta ca markers and atopic disease in our population. In addition, these markers have shown a high percentage of homozygosis.Conclusions: IL4-R1 and Fc epsilon RI-beta ca markers have not proved to be useful genetic markers for linkage or association studies in our population. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Allergy: European Journal of Allergy and Clinical Immunology | en_US |
dc.source | Allergy: European Journal of Allergy and Clinical Immunology [ISSN 0105-4538],v. 56(2), p. 159-163, (Febrero 2001) | en_US |
dc.subject | 32 Ciencias médicas | en_US |
dc.subject | 320102 Genética clínica | en_US |
dc.subject | 320701 Alergias | en_US |
dc.subject.other | Serum Ige Levels | en_US |
dc.subject.other | Immunoglobulin-E | en_US |
dc.subject.other | Linkage Analysis | en_US |
dc.subject.other | Chromosome 5Q31 | en_US |
dc.subject.other | Canary-Islands | en_US |
dc.subject.other | Receptor Gene | en_US |
dc.subject.other | P-I | en_US |
dc.subject.other | Families | en_US |
dc.subject.other | Asthma | en_US |
dc.subject.other | Association | en_US |
dc.title | IL4-R1 (5q31–q33) and FcεRI-βca (11q13) markers and atopy: a case/control study in a Spanish population | en_US |
dc.type | info:eu-repo/semantics/article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1034/j.1398-9995.2001.056002159.x | en_US |
dc.identifier.scopus | 2-s2.0-0035150895 | - |
dc.identifier.scopus | 0035150895 | - |
dc.identifier.isi | 000166777900010 | - |
dcterms.isPartOf | Allergy | - |
dcterms.source | Allergy[ISSN 0105-4538],v. 56 (2), p. 159-163 | - |
dc.contributor.authorscopusid | 6602512211 | - |
dc.contributor.authorscopusid | 7003929627 | - |
dc.contributor.authorscopusid | 56149756400 | - |
dc.contributor.authorscopusid | 7004458460 | - |
dc.contributor.authorscopusid | 57189070218 | - |
dc.contributor.authorscopusid | 7202163438 | - |
dc.contributor.authorscopusid | 7003526269 | - |
dc.contributor.authorscopusid | 6602739743 | - |
dc.contributor.authorscopusid | 7003798054 | - |
dc.description.lastpage | 163 | en_US |
dc.identifier.issue | 2 | - |
dc.description.firstpage | 159 | en_US |
dc.relation.volume | 56 | en_US |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.identifier.wos | WOS:000166777900010 | - |
dc.contributor.daisngid | 4389609 | - |
dc.contributor.daisngid | 380971 | - |
dc.contributor.daisngid | 865329 | - |
dc.contributor.daisngid | 29540068 | - |
dc.contributor.daisngid | 344429 | - |
dc.contributor.daisngid | 282788 | - |
dc.contributor.daisngid | 16409 | - |
dc.contributor.daisngid | 3283908 | - |
dc.contributor.daisngid | 400206 | - |
dc.contributor.daisngid | 3148254 | - |
dc.contributor.daisngid | 3334871 | - |
dc.contributor.daisngid | 1171573 | - |
dc.identifier.investigatorRID | C-1733-2016 | - |
dc.identifier.investigatorRID | B-3895-2012 | - |
dc.identifier.investigatorRID | A-9640-2017 | - |
dc.description.numberofpages | 5 | en_US |
dc.utils.revision | Sí | en_US |
dc.contributor.wosstandard | WOS:Torres-Galvan, MJ | - |
dc.contributor.wosstandard | WOS:Quiralte, J | - |
dc.contributor.wosstandard | WOS:Pestano, JJ | - |
dc.contributor.wosstandard | WOS:Ortega, N | - |
dc.contributor.wosstandard | WOS:Blanco, C | - |
dc.contributor.wosstandard | WOS:Castillo, R | - |
dc.contributor.wosstandard | WOS:Carrillo, T | - |
dc.contributor.wosstandard | WOS:Perez-Aciego, P | - |
dc.contributor.wosstandard | WOS:Sanchez-Garcia, F | - |
dc.date.coverdate | Febrero 2001 | en_US |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-MED | en_US |
dc.description.jcr | 2,852 | - |
dc.description.jcrq | Q1 | - |
dc.description.scie | SCIE | - |
item.grantfulltext | none | - |
item.fulltext | Sin texto completo | - |
crisitem.author.dept | GIR IUIBS: Medio Ambiente y Salud | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología | - |
crisitem.author.dept | GIR IUIBS: Patología y Tecnología médica | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Ciencias Médicas y Quirúrgicas | - |
crisitem.author.orcid | 0000-0001-6454-4785 | - |
crisitem.author.orcid | 0000-0002-3047-8908 | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.fullName | Pestano Brito, José Juan | - |
crisitem.author.fullName | Carrillo Díaz, Teresa | - |
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