Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/46995
Campo DC Valoridioma
dc.contributor.authorTorres-Galván, M.en_US
dc.contributor.authorQuiralte, J.en_US
dc.contributor.authorPestano, J. J.en_US
dc.contributor.authorOrtega, N.en_US
dc.contributor.authorBlanco, C.en_US
dc.contributor.authorCastillo, R.en_US
dc.contributor.authorCarrillo, T.en_US
dc.contributor.authorPérez-Aciego, P.en_US
dc.contributor.authorSánchez-García, F.en_US
dc.contributor.otherIBIS, ALERGICAS-
dc.contributor.otherBlanco, Carlos-
dc.contributor.otherPestano Brito, Jose Juan-
dc.date.accessioned2018-11-23T10:00:55Z-
dc.date.available2018-11-23T10:00:55Z-
dc.date.issued2001en_US
dc.identifier.issn0105-4538en_US
dc.identifier.urihttp://hdl.handle.net/10553/46995-
dc.description.abstractBackground: Rhinoconjunctivitis and bronchial asthma are atopic diseases with a high prevalence in the Canary Islands (Spain). Given that the most prevalent allergen is the house-dust mite Dermatophagoides pteronyssinus, early detection of genetically susceptible subjects would allow the application of preventive measures. The objective was to investigate the possible association of IL4-R1 (chromosome 5q31-q33) and Fc epsilon RI-beta ca (chromosome 11q13) markers with the atopic disease in our population.Methods: We performed a case/control study in which patients were recruited on the basis of diagnosis of rhinoconjunctivitis and/or bronchial asthma, and positive skin prick test to D. pteronyssinus. Analysis of IL4-R1 and Fc epsilon RI-beta ca microsatellites was carried out by PCR and electrophoresis in acrylamide gels.Results: We have not found evidence of association between IL4-R1 and Fc epsilon RI-beta ca markers and atopic disease in our population. In addition, these markers have shown a high percentage of homozygosis.Conclusions: IL4-R1 and Fc epsilon RI-beta ca markers have not proved to be useful genetic markers for linkage or association studies in our population.en_US
dc.languageengen_US
dc.relation.ispartofAllergy: European Journal of Allergy and Clinical Immunologyen_US
dc.sourceAllergy: European Journal of Allergy and Clinical Immunology [ISSN 0105-4538],v. 56(2), p. 159-163, (Febrero 2001)en_US
dc.subject32 Ciencias médicasen_US
dc.subject320102 Genética clínicaen_US
dc.subject320701 Alergiasen_US
dc.subject.otherSerum Ige Levelsen_US
dc.subject.otherImmunoglobulin-Een_US
dc.subject.otherLinkage Analysisen_US
dc.subject.otherChromosome 5Q31en_US
dc.subject.otherCanary-Islandsen_US
dc.subject.otherReceptor Geneen_US
dc.subject.otherP-Ien_US
dc.subject.otherFamiliesen_US
dc.subject.otherAsthmaen_US
dc.subject.otherAssociationen_US
dc.titleIL4-R1 (5q31–q33) and FcεRI-βca (11q13) markers and atopy: a case/control study in a Spanish populationen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1034/j.1398-9995.2001.056002159.xen_US
dc.identifier.scopus2-s2.0-0035150895-
dc.identifier.scopus0035150895-
dc.identifier.isi000166777900010-
dcterms.isPartOfAllergy-
dcterms.sourceAllergy[ISSN 0105-4538],v. 56 (2), p. 159-163-
dc.contributor.authorscopusid6602512211-
dc.contributor.authorscopusid7003929627-
dc.contributor.authorscopusid56149756400-
dc.contributor.authorscopusid7004458460-
dc.contributor.authorscopusid57189070218-
dc.contributor.authorscopusid7202163438-
dc.contributor.authorscopusid7003526269-
dc.contributor.authorscopusid6602739743-
dc.contributor.authorscopusid7003798054-
dc.description.lastpage163en_US
dc.identifier.issue2-
dc.description.firstpage159en_US
dc.relation.volume56en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.identifier.wosWOS:000166777900010-
dc.contributor.daisngid4389609-
dc.contributor.daisngid380971-
dc.contributor.daisngid865329-
dc.contributor.daisngid29540068-
dc.contributor.daisngid344429-
dc.contributor.daisngid282788-
dc.contributor.daisngid16409-
dc.contributor.daisngid3283908-
dc.contributor.daisngid400206-
dc.contributor.daisngid3148254-
dc.contributor.daisngid3334871-
dc.contributor.daisngid1171573-
dc.identifier.investigatorRIDC-1733-2016-
dc.identifier.investigatorRIDB-3895-2012-
dc.identifier.investigatorRIDA-9640-2017-
dc.description.numberofpages5en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Torres-Galvan, MJ-
dc.contributor.wosstandardWOS:Quiralte, J-
dc.contributor.wosstandardWOS:Pestano, JJ-
dc.contributor.wosstandardWOS:Ortega, N-
dc.contributor.wosstandardWOS:Blanco, C-
dc.contributor.wosstandardWOS:Castillo, R-
dc.contributor.wosstandardWOS:Carrillo, T-
dc.contributor.wosstandardWOS:Perez-Aciego, P-
dc.contributor.wosstandardWOS:Sanchez-Garcia, F-
dc.date.coverdateFebrero 2001en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.jcr2,852-
dc.description.jcrqQ1-
dc.description.scieSCIE-
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología-
crisitem.author.deptGIR IUIBS: Patología y Tecnología médica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0001-6454-4785-
crisitem.author.orcid0000-0002-3047-8908-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNamePestano Brito, José Juan-
crisitem.author.fullNameCarrillo Díaz, Teresa-
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