Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/46791
DC FieldValueLanguage
dc.contributor.authorBoronat, Mauro
dc.contributor.authorGarcía-Cantón, César
dc.contributor.authorQuevedo, Virginia
dc.contributor.authorLorenzo, Dionisio L.
dc.contributor.authorLópez-Ríos, Laura
dc.contributor.authorBatista, Fátima
dc.contributor.authorRiaño, Marta
dc.contributor.authorSaavedra, Pedro
dc.contributor.authorCheca, María D.
dc.date.accessioned2018-11-23T08:13:57Z-
dc.date.available2018-11-23T08:13:57Z-
dc.date.issued2014
dc.identifier.issn0886-022X
dc.identifier.urihttp://hdl.handle.net/10553/46791-
dc.description.abstractUrinary albumin excretion has been consistently found to be normal in a significant number of subjects with early stages of diabetic kidney disease. This study was aimed to estimate the prevalence and characteristics of non-albuminuric chronic kidney disease associated with type 2 diabetes mellitus among subjects who reach advanced stages of renal failure. Study population was composed of incident patients with advanced chronic kidney disease (glomerular filtration rate <30 mL/min) related to type 2 diabetes in a tertiary hospital from Gran Canaria (Spain) during a period of 2 years. Subjects were classified as normoalbuminuric (urinary albumin-to-creatine ratio [UACR] <30 mg/g), microalbuminuric (UACR >= 30 and 5300 mg/g), or proteinuric (UACR >= 300 mg/g). Of 78 eligible patients, 21.8% had normoalbuminuria, 20.5% had microalbuminuria, and 57.7% had proteinuria. Individuals with normoalbuminuria were mostly women and had a lower prevalence of smoking and polyneuropathy than subjects with microalbuminuria or proteinuria. They also presented greater measures of body mass index and waist circumference, higher values of total and LDL cholesterol, and lower values of HbA(1c) and serum creatinine than subjects with microalbuminuria or proteinuria. Multivariate analysis demonstrated that female sex (positively) and HbA(1c) and polyneuropathy (negatively) were independently associated with absence of albuminuria. In conclusion, around 20% of subjects with diabetes-related advanced chronic kidney disease, characteristically women, have normal urinary albumin excretion. HbA(1c) and polyneuropathy are inversely related to this non-albuminuric form of nephropathy.
dc.publisher0886-022X
dc.relation.ispartofRenal Failure
dc.sourceRenal Failure[ISSN 0886-022X],v. 36, p. 166-170
dc.subject.otherRisk-Factors
dc.subject.otherSerum Creatinine
dc.subject.otherNephropathy
dc.subject.otherPopulation
dc.subject.otherInsufficiency
dc.subject.otherRetinopathy
dc.subject.otherImpairment
dc.subject.otherPrediction
dc.subject.otherNeuropathy
dc.subject.otherNiddm
dc.titleNon-albuminuric renal disease among subjects with advanced stages of chronic kidney failure related to type 2 diabetes mellitus
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.doi10.3109/0886022X.2013.835266
dc.identifier.scopus84896694644-
dc.identifier.isi000333168000003
dc.contributor.authorscopusid7003952293
dc.contributor.authorscopusid6603127359
dc.contributor.authorscopusid50561862600
dc.contributor.authorscopusid55967938300
dc.contributor.authorscopusid33068166900
dc.contributor.authorscopusid55968288300
dc.contributor.authorscopusid37067926100
dc.contributor.authorscopusid56677724200
dc.contributor.authorscopusid6701336412
dc.description.lastpage170
dc.description.firstpage166
dc.relation.volume36
dc.type2Artículoes
dc.contributor.daisngid673494
dc.contributor.daisngid1915819
dc.contributor.daisngid5112593
dc.contributor.daisngid30519221
dc.contributor.daisngid1964185
dc.contributor.daisngid5867919
dc.contributor.daisngid5257474
dc.contributor.daisngid247998
dc.contributor.daisngid1016886
dc.contributor.wosstandardWOS:Boronat, M
dc.contributor.wosstandardWOS:Garcia-Canton, C
dc.contributor.wosstandardWOS:Quevedo, V
dc.contributor.wosstandardWOS:Lorenzo, DL
dc.contributor.wosstandardWOS:Lopez-Rios, L
dc.contributor.wosstandardWOS:Batista, F
dc.contributor.wosstandardWOS:Riano, M
dc.contributor.wosstandardWOS:Saavedra, P
dc.contributor.wosstandardWOS:Checa, MD
dc.date.coverdateEnero 2014
dc.identifier.ulpgces
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptDiabetes y endocrinología aplicada-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0001-8535-8543-
crisitem.author.orcid0000-0002-5988-8222-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameBoronat Cortés, Mauro-
crisitem.author.fullNameGarcía Cantón, César-
crisitem.author.fullNameLorenzo Villegas, Dionisio Lorenzo-
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