Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/46649
Título: Impact of nosocomial pneumonia on the outcome of mechanically-ventilated patients
Autores/as: Sole Violan, Jorge 
Sánchez-Ramírez, C.
Padrón Mújica, A.
Cardeñosa Cendrero, J. A.
Arroyo Fernández, J.
Rodríguez De Castro, F. 
Clasificación UNESCO: 32 Ciencias médicas
3202 Epidemologia
3205 Medicina interna
Palabras clave: Nosocomial diseases
Pneumonia
Mechanically-ventilated patients
Fecha de publicación: 1998
Publicación seriada: Critical Care 
Resumen: Background Nosocomial pneumonia (NP) is a common complication in mechanically-ventilated patients and is considered to be one of the most common causes of morbidity and mortality. However, assessment of the associated mortality is not staightforward as it shares several risk factors with NP that confound the relationship. The aim of this study was to evaluate the impact of NP on the mortality rate in an intensive care unit. During the study period (January-December 1995) all patients under mechanical ventilation for a period > 48 h (n = 314) were prospectively evaluated, and the prognostic factors of NP, which have been identified in previous studies, were recorded. Results Pneumonia was diagnosed in 82 patients. The overall mortality rate was 34% for patients with NP compared to 17% in those without NP. Multivariate analysis selected the following three prognostic factors as being significantly associated with a higher risk of death: the presence of multiple organ failure [odds ratio (OR) 6.71, 95% CI, P < 0.001]; the presence of adult respiratory distress syndrome (ARDS) (OR 3.03, 95% CI, P < 0.01), and simplified acute physiology score (SAPS)> 9(OR 2.89, 95% CI, P < 0.05). Conclusions In mechanically-ventilated patients NP does not represent an independent risk factor for mortality. Markers of severity of illness were the strongest predictors for mortality.
URI: http://hdl.handle.net/10553/46649
ISSN: 1364-8535
DOI: 10.1186/cc119
Fuente: Critical Care[ISSN 1364-8535],v. 2, p. 19-23
Colección:Artículos
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