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Title: Marine sponge lectins: actual status on properties and biological activities
Authors: Filho, Sandro Mascena Gomes
Cardoso, Juscélio Donizete
Anaya, Katya
Do Nascimento, Edilza Silva
De Lacerda, José Thalles Jucelino Gomes
Mioso, R. 
Gadelha, Tatiane Santi
De Almeida Gadelha, Carlos Alberto
UNESCO Clasification: 2415 Biología molecular
23 Química
Keywords: Marine sponge
Biological activities
Issue Date: 2015
Journal: Molecules 
Abstract: Marine sponges are primitive metazoans that produce a wide variety of molecules that protect them against predators. In studies that search for bioactive molecules, these marine invertebrates stand out as promising sources of new biologically-active molecules, many of which are still unknown or little studied; thus being an unexplored biotechnological resource of high added value. Among these molecules, lectins are proteins that reversibly bind to carbohydrates without modifying them. In this review, various structural features and biological activities of lectins derived from marine sponges so far described in the scientific literature are discussed. From the results found in the literature, it could be concluded that lectins derived from marine sponges are structurally diverse proteins with great potential for application in the production of biopharmaceuticals, especially as antibacterial and antitumor agents.
ISSN: 1420-3049
DOI: 10.3390/molecules20010348
Source: Molecules [1420-3049], v. 20 (1), p. 348-357
Appears in Collections:Reseña
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