Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/45519
DC Field | Value | Language |
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dc.contributor.author | Romero-Alemán, María del Mar | |
dc.contributor.author | Monzón-Mayor, Maximina | |
dc.contributor.author | Yanes, Carmen | |
dc.contributor.author | Arbelo-Galván, Juan Francisco | |
dc.contributor.author | Lang, Dirk | |
dc.contributor.author | Renau-Piqueras, Jaime | |
dc.contributor.author | Negrín-Martínez, Ciro | |
dc.contributor.other | Lang, Dirk | |
dc.contributor.other | ROMERO-ALEMAN, MARIA DEL MAR | |
dc.contributor.other | Monzon-Mayor, Maximina | |
dc.date.accessioned | 2018-11-22T10:28:52Z | - |
dc.date.available | 2018-11-22T10:28:52Z | - |
dc.date.issued | 2003 | |
dc.identifier.issn | 0022-3034 | |
dc.identifier.uri | http://hdl.handle.net/10553/45519 | - |
dc.description.abstract | We identified S100 immunoreactive cells in the brain of the lizard Gallotia galloti during ontogeny using immunohistochemical techniques for light and electron microscopy. In double labeling experiments with antibodies specific for S100A1 and S100B (anti-S100) and proliferative cell nuclear antigen (anti-PCNA), myelin basic protein (anti-MBP), phosphorylated neurofilaments (SMI-31), glial fibrillary acidic protein (anti-GFAP), or glutamine synthetase (anti-GS), we detected S100-like immunoreactivity in glial cells but never in neurons. Restricted areas of the ventricular zone were stained in the hypothalamus from E32 to postnatal stages, and in the telencephalon at E35, E36, and in adults. S100 immunoreactivity was observed predominantly in scattered PCNA-negative cells that increased in number from E35 to the adult stage in the myelinated tracts of the brain and had the appearance of oligodendrocytes. Quantitative analysis revealed that all of the S100-positive glial cells were GFAP-negative, whereas most of the S100-positive glial cells were GS-positive. Ultrastructurally, most of these S100-positive/GS-positive glial cells resembled oligodendrocytes of light and medium electron density. In adult lizards, a small subpopulation of astrocyte-like cells was also stained in the pretectum. We conclude that in the lizard S100 can be considered a marker of a subpopulation of oligodendrocytes rather than of astrocytes, as is the case in mammals. The S100-positive subpopulation of oligodendrocytes in the lizard could represent cells actively involved in the process of myelination during development and in the maintenance of myelin sheaths in the adult. (C) 2003 Wiley Periodicals, Inc. | |
dc.publisher | 0022-3034 | |
dc.relation.ispartof | Journal of Neurobiology | |
dc.source | Journal of Neurobiology[ISSN 0022-3034],v. 57, p. 54-66 | |
dc.subject.other | Myelin Basic-Protein | |
dc.subject.other | Rat Optic-Nerve | |
dc.subject.other | Immunohistochemical Localization | |
dc.subject.other | Visual-Cortex | |
dc.subject.other | S-100 Protein | |
dc.subject.other | Adult-Rat | |
dc.subject.other | Oligodendrocytes | |
dc.subject.other | Brain | |
dc.subject.other | Gliogenesis | |
dc.subject.other | Expression | |
dc.title | S100 immunoreactive glial cells in the forebrain and midbrain of the lizard Gallotia galloti during ontogeny | |
dc.type | info:eu-repo/semantics/Article | es |
dc.type | Article | es |
dc.identifier.doi | 10.1002/neu.10258 | |
dc.identifier.scopus | 0042385112 | - |
dc.identifier.isi | 000185210700005 | |
dcterms.isPartOf | Journal Of Neurobiology | |
dcterms.source | Journal Of Neurobiology[ISSN 0022-3034],v. 57 (1), p. 54-66 | |
dc.contributor.authorscopusid | 6506533545 | |
dc.contributor.authorscopusid | 36793900900 | |
dc.contributor.authorscopusid | 7004187530 | |
dc.contributor.authorscopusid | 6506602441 | |
dc.contributor.authorscopusid | 7202375282 | |
dc.contributor.authorscopusid | 7006666243 | |
dc.contributor.authorscopusid | 6505525090 | |
dc.description.lastpage | 66 | |
dc.description.firstpage | 54 | |
dc.relation.volume | 57 | |
dc.type2 | Artículo | es |
dc.identifier.wos | WOS:000185210700005 | |
dc.contributor.daisngid | 1157526 | |
dc.contributor.daisngid | 901526 | |
dc.contributor.daisngid | 675718 | |
dc.contributor.daisngid | 5740302 | |
dc.contributor.daisngid | 626938 | |
dc.contributor.daisngid | 451790 | |
dc.contributor.daisngid | 11865715 | |
dc.identifier.investigatorRID | I-2554-2015 | |
dc.identifier.investigatorRID | K-8038-2014 | |
dc.identifier.investigatorRID | No ID | |
dc.contributor.wosstandard | WOS:Romero-Aleman, MD | |
dc.contributor.wosstandard | WOS:Monzon-Mayor, M | |
dc.contributor.wosstandard | WOS:Yanes, C | |
dc.contributor.wosstandard | WOS:Arbelo-Galvan, JF | |
dc.contributor.wosstandard | WOS:Lang, D | |
dc.contributor.wosstandard | WOS:Renau-Piqueras, J | |
dc.contributor.wosstandard | WOS:Negrin-Martinez, C | |
dc.date.coverdate | Octubre 2003 | |
dc.identifier.ulpgc | Sí | es |
dc.description.jcr | 3,145 | |
dc.description.jcrq | Q2 | |
item.fulltext | Sin texto completo | - |
item.grantfulltext | none | - |
crisitem.author.dept | GIR IUIBS: Farmacología Molecular y Traslacional | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.dept | Departamento de Morfología | - |
crisitem.author.dept | GIR IUIBS: Tecnología Médica y Audiovisual | - |
crisitem.author.dept | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.orcid | 0000-0002-7987-5509 | - |
crisitem.author.orcid | 0000-0002-5046-508X | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.parentorg | IU de Investigaciones Biomédicas y Sanitarias | - |
crisitem.author.fullName | Romero Alemán, María Del Mar | - |
crisitem.author.fullName | Monzón Mayor,Maximina | - |
crisitem.author.fullName | Yanes Mendez, Carmen M | - |
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