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Title: EURRECA-Estimating Zinc Requirements for Deriving Dietary Reference Values
Authors: Lowe, Nicola M.
Dykes, Fiona C.
Skinner, Anna Louise
Patel, Sujata
Warthon-Medina, Marisol
Decsi, Tamás
Fekete, Katalin
Souverein, Olga W.
Dullemeijer, Carla
Cavelaars, Adriënne E.
Serra-Majem, Lluis 
Nissensohn, Mariela 
Bel, Silvia
Moreno, Luis A.
Hermoso, Maria
Vollhardt, Christiane
Berti, Cristiana
Cetin, Irene
Gurinovic, Mirjana
Novakovic, Romana
Harvey, Linda J.
Collings, Rachel
Hall-Moran, Victoria
Keywords: Coronary-Artery-Disease
Serum Zinc
Stable-Isotope, et al
Issue Date: 2013
Publisher: 1040-8398
Journal: Critical Reviews in Food Science and Nutrition 
Abstract: Zinc was selected as a priority micronutrient for EURRECA, because there is significant heterogeneity in the Dietary Reference Values (DRVs) across Europe. In addition, the prevalence of inadequate zinc intakes was thought to be high among all population groups worldwide, and the public health concern is considerable. In accordance with the EURRECA consortium principles and protocols, a series of literature reviews were undertaken in order to develop best practice guidelines for assessing dietary zinc intake and zinc status. These were incorporated into subsequent literature search strategies and protocols for studies investigating the relationships between zinc intake, status and health, as well as studies relating to the factorial approach (including bioavailability) for setting dietary recommendations. EMBASE (Ovid), Cochrane Library CENTRAL, and MEDLINE (Ovid) databases were searched for studies published up to February 2010 and collated into a series of Endnote databases that are available for the use of future DRV panels. Meta-analyses of data extracted from these publications were performed where possible in order to address specific questions relating to factors affecting dietary recommendations. This review has highlighted the need for more high quality studies to address gaps in current knowledge, in particular the continued search for a reliable biomarker of zinc status and the influence of genetic polymorphisms on individual dietary requirements. In addition, there is a need to further develop models of the effect of dietary inhibitors of zinc absorption and their impact on population dietary zinc requirements.
ISSN: 1040-8398
DOI: 10.1080/10408398.2012.742863
Source: Critical Reviews in Food Science and Nutrition[ISSN 1040-8398],v. 53, p. 1110-1123
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