Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/44665
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dc.contributor.authorBuil-Cosiales, Pilar
dc.contributor.authorZazpe, Itziar
dc.contributor.authorToledo, Estefania
dc.contributor.authorCorella, Dolores
dc.contributor.authorSalas-Salvadó, Jordi
dc.contributor.authorDiez-Espino, Javier
dc.contributor.authorRos, Emilio
dc.contributor.authorNavajas, Joaquin Fernandez Creuet
dc.contributor.authorSantos-Lozano, José Manuel
dc.contributor.authorArós, Fernando
dc.contributor.authorFiol, Miquel
dc.contributor.authorCastaner, Olga
dc.contributor.authorSerra-Majem, Lluis
dc.contributor.authorPintó, Xavier
dc.contributor.authorLamuela-Raventós, Rosa M.
dc.contributor.authorMarti, Amelia
dc.contributor.authorBasterra-Gortari, F. Javier
dc.contributor.authorSorli, José V.
dc.contributor.authorVerdú-Rotellar, Jose Ma
dc.contributor.authorBasora, Josep
dc.contributor.authorRuiz-Gutierrez, Valentina
dc.contributor.authorEstruch, Ramón
dc.contributor.authorMartínez-González, Miguel A.
dc.date.accessioned2018-11-22T01:29:26Z-
dc.date.available2018-11-22T01:29:26Z-
dc.date.issued2014
dc.identifier.issn0002-9165
dc.identifier.urihttp://hdl.handle.net/10553/44665-
dc.description.abstractBackground: Few observational studies have examined the effect of dietary fiber intake and fruit and vegetable consumption on total mortality and have reported inconsistent results. All of the studies have been conducted in the general population and typically used only a single assessment of diet.Objective: We investigated the association of fiber intake and whole-grain, fruit, and vegetable consumption with all-cause mortality in a Mediterranean cohort of elderly adults at high cardiovascular disease (CVD) risk by using repeated measurements of dietary information and taking into account the effect of a dietary intervention.Design: We followed up 7216 men (55-75 y old) and women (60-75 y old) at high CVD risk in the Prevencion con Dieta Mediterranea (PREDIMED) trial for a mean of 5.9 y. Data were analyzed as an observational cohort. Participants were initially free of CVD. A 137-item validated food-frequency questionnaire administered by dietitians was repeated annually to assess dietary exposures (fiber, fruit, vegetable, and whole-grain intakes). Deaths were identified through the continuing medical care of participants and the National Death Index. An independent, blinded Event Adjudication Committee adjudicated causes of death. Cox regression models were used to estimate HRs of death during follow-up according to baseline dietary exposures and their yearly updated changes.Results: In up to 8.7 y of follow-up, 425 participants died. Baseline fiber intake and fruit consumption were significantly associated with lower risk of death [HRs for the fifth compared with the first quintile: 0.63 (95% Cl: 0.46, 0.86; P = 0.015) and 0.59 (95% Cl: 0.42, 0.82; P = 0.004), respectively]. When the updated dietary information was considered, participants with fruit consumption >210 g/d had 41% lower risk of all-cause mortality (HR: 0.59; 95% CI: 0.44, 0.78). Associations were strongest for CVD mortality than other causes of death.Conclusion: Fiber and fruit intakes are associated with a reduction in total mortality. PREDIMED was registered at controlled-trials.com as ISRCTN35739639.
dc.publisher0002-9165
dc.relation.ispartofThe American journal of clinical nutrition
dc.sourceAmerican Journal of Clinical Nutrition[ISSN 0002-9165],v. 100, p. 1498-1507
dc.subject.otherCoronary-Heart-Disease
dc.subject.otherTotal-Energy Intake
dc.subject.otherCardiovascular-Disease
dc.subject.otherVegetable Consumption
dc.subject.otherFollow-Up
dc.subject.otherNational-Health
dc.subject.otherReduced Risk
dc.subject.otherVitamin-C
dc.subject.otherFruit
dc.subject.otherCohort
dc.titleFiber intake and all-cause mortality in the Prevención con Dieta Mediterránea (PREDIMED) study
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.doi10.3945/ajcn.114.093757
dc.identifier.scopus84911457414-
dc.identifier.isi000345267600013
dc.contributor.authorscopusid26029100700
dc.contributor.authorscopusid24385723800
dc.contributor.authorscopusid7003562288
dc.contributor.authorscopusid7003570538
dc.contributor.authorscopusid7003357665
dc.contributor.authorscopusid6603398696
dc.contributor.authorscopusid35474202600
dc.contributor.authorscopusid6506413888
dc.contributor.authorscopusid6602779360
dc.contributor.authorscopusid7004158382
dc.contributor.authorscopusid7005315313
dc.contributor.authorscopusid36487707800
dc.contributor.authorscopusid35596972100
dc.contributor.authorscopusid7004430064
dc.contributor.authorscopusid7003644939
dc.contributor.authorscopusid7102814881
dc.contributor.authorscopusid16306349400
dc.contributor.authorscopusid7004605575
dc.contributor.authorscopusid6507987969
dc.contributor.authorscopusid23017786300
dc.contributor.authorscopusid7004979765
dc.contributor.authorscopusid7005989830
dc.contributor.authorscopusid7004290629
dc.description.lastpage1507
dc.description.firstpage1498
dc.relation.volume100
dc.type2Artículoes
dc.contributor.daisngid1132156
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dc.contributor.daisngid19357
dc.contributor.daisngid17754
dc.contributor.wosstandardWOS:Buil-Cosiales, P
dc.contributor.wosstandardWOS:Zazpe, I
dc.contributor.wosstandardWOS:Toledo, E
dc.contributor.wosstandardWOS:Corella, D
dc.contributor.wosstandardWOS:Salas-Salvado, J
dc.contributor.wosstandardWOS:Diez-Espino, J
dc.contributor.wosstandardWOS:Ros, E
dc.contributor.wosstandardWOS:Navajas, JFC
dc.contributor.wosstandardWOS:Santos-Lozano, JM
dc.contributor.wosstandardWOS:Aros, F
dc.contributor.wosstandardWOS:Fiol, M
dc.contributor.wosstandardWOS:Castaner, O
dc.contributor.wosstandardWOS:Serra-Majem, L
dc.contributor.wosstandardWOS:Pinto, X
dc.contributor.wosstandardWOS:Lamuela-Raventos, RM
dc.contributor.wosstandardWOS:Marti, A
dc.contributor.wosstandardWOS:Basterra-Gortari, FJ
dc.contributor.wosstandardWOS:Sorli, JV
dc.contributor.wosstandardWOS:Verdu-Rotellar, JM
dc.contributor.wosstandardWOS:Basora, J
dc.contributor.wosstandardWOS:Ruiz-Gutierrez, V
dc.contributor.wosstandardWOS:Estruch, R
dc.contributor.wosstandardWOS:Martinez-Gonzalez, MA
dc.date.coverdateEnero 2014
dc.identifier.ulpgces
dc.description.sjr3,799
dc.description.jcr6,77
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Nutrición-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.orcid0000-0002-9658-9061-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameSerra Majem, Luis-
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