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http://hdl.handle.net/10553/44599
| Title: | Association of Tryptophan Metabolites with Incident Type 2 Diabetes in the PREDIMED Trial: A Case-Cohort Study | Authors: | Yu, Edward Papandreou, Christopher Ruiz-Canela, Miguel Guasch-Ferre, Marta Clish, Clary B. Dennis, Courtney Liang, Liming Corella, Dolores Fitó, Montserrat Razquin, Cristina Lapetra, José Estruch, Ramón Ros, Emilio Cofán, Montserrat Arós, Fernando Toledo, Estefania Serra-Majem, Lluis Sorlí, José V. Hu, Frank B. Martinez-Gonzalez, Miguel A. Salas-Salvado, Jordi |
UNESCO Clasification: | 2403 Bioquímica 2301 química analítica |
Keywords: | Diabetes Insulin Metabolites Risk analysis Cardiovascular disease |
Issue Date: | 2018 | Publisher: | 0009-9147 | Journal: | Clinical chemistry (Baltimore, Md.) | Abstract: | BACKGROUND: Metabolites of the tryptophan-kynurenine pathway (i.e., tryptophan, kynurenine, kynurenic acid, quinolinic acid, 3-hydroxyanthranilic) may be associated with diabetes development. Using a case-cohort design nested in the Prevencion con Dieta Mediterranea (PREDIMED) study, we studied the associations of baseline and 1-year changes of these metabolites with incident type 2 diabetes (T2D). | URI: | http://hdl.handle.net/10553/44599 | ISSN: | 0009-9147 | DOI: | 10.1373/clinchem.2018.288720 | Source: | Clinical Chemistry [ISSN 0009-9147], v. 64 (8), p. 1211-1220 |
| Appears in Collections: | Artículos |
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