Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/43373
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Rodríguez Guisado, Francisco | en_US |
dc.contributor.author | Ramírez, G. A. | en_US |
dc.contributor.author | Sarradell, J. | en_US |
dc.contributor.author | Andrada Borzollino, Marisa Ana | en_US |
dc.contributor.author | Lorenzo, H. | en_US |
dc.date.accessioned | 2018-11-21T14:39:43Z | - |
dc.date.available | 2018-11-21T14:39:43Z | - |
dc.date.issued | 2004 | en_US |
dc.identifier.issn | 0021-9975 | en_US |
dc.identifier.uri | http://hdl.handle.net/10553/43373 | - |
dc.description.abstract | Mycoplasma hyopneumoniae (Mh) is the primary agent of porcine enzootic pneumonia (PEN), a chronic respiratory disease endemic to pig farms, and characterized histologically by infiltration of mononuclear cells in airways and prominent hyperplasia of the bronchus-associated lymphoid tissue (BALT). To gain further insight into the pathogenesis of PEN, cytokine expression in the lung, with particular attention to the BALT, was examined immunohistochemically in pigs naturally infected with Mh. An increase (P<0.05) in proinflammatory and immunoregulatory cytokines (especially interleukin [IL]-2, IL-4 and tumour necrosis factor [TNF]-α, and to a lesser extent IL-1 [α and β] and IL-6) was detected in the BALT, which showed intense lymphoid hyperplasia. IL-1β and TNF-α were also detected in the bronchoalveolar exudate of infected pigs, and IL-6 and IL-8 were demonstrated in mononuclear cells of the alveolar septa. The results showed that in Mh infection, macrophage and lymphocyte activation results in the expression of a number of cytokines capable of inducing lung lesions and lymphoreticular hyperplasia of the BALT. | en_US |
dc.language | eng | en_US |
dc.publisher | 0021-9975 | - |
dc.relation.ispartof | Journal of Comparative Pathology | en_US |
dc.source | Journal of Comparative Pathology [ISSN 0021-9975], v. 130(4), p. 306-312 | en_US |
dc.subject | 310907 Patología | en_US |
dc.subject.other | Bacterial infection | en_US |
dc.subject.other | Cytokine | en_US |
dc.subject.other | Mycoplasma hyopneumoniae | en_US |
dc.subject.other | Pig | en_US |
dc.subject.other | Porcine enzootic pneumonia | en_US |
dc.title | Immunohistochemical labelling of cytokines in lung lesions of pigs naturally infected with Mycoplasma hyopneumoniae | en_US |
dc.type | info:eu-repo/semantics/Article | es |
dc.type | Article | es |
dc.identifier.doi | 10.1016/j.jcpa.2003.12.008 | - |
dc.identifier.scopus | 1842639413 | - |
dc.identifier.isi | 000220833900009 | - |
dc.contributor.authorscopusid | 21641919200 | - |
dc.contributor.authorscopusid | 25623593400 | - |
dc.contributor.authorscopusid | 6602259861 | - |
dc.contributor.authorscopusid | 6602991535 | - |
dc.contributor.authorscopusid | 6603882730 | - |
dc.description.lastpage | 312 | - |
dc.description.firstpage | 306 | - |
dc.relation.volume | 130 | - |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.contributor.daisngid | 2263409 | - |
dc.contributor.daisngid | 389144 | - |
dc.contributor.daisngid | 3902685 | - |
dc.contributor.daisngid | 862879 | - |
dc.contributor.daisngid | 4983330 | - |
dc.contributor.wosstandard | WOS:Rodriguez, F | - |
dc.contributor.wosstandard | WOS:Ramirez, GA | - |
dc.contributor.wosstandard | WOS:Sarradell, J | - |
dc.contributor.wosstandard | WOS:Andrada, M | - |
dc.contributor.wosstandard | WOS:Lorenzo, H | - |
dc.date.coverdate | Enero 2004 | - |
dc.identifier.ulpgc | Sí | es |
dc.description.jcr | 1,365 | |
dc.description.jcrq | Q1 | |
dc.description.scie | SCIE | |
item.grantfulltext | none | - |
item.fulltext | Sin texto completo | - |
crisitem.author.dept | GIR IUSA-ONEHEALTH1: Epidemiología, Medicina Preventiva Veterinaria y Zoonosis | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Morfología | - |
crisitem.author.dept | GIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina) | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Morfología | - |
crisitem.author.orcid | 0000-0002-4968-5333 | - |
crisitem.author.orcid | 0000-0002-2411-9714 | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.fullName | Rodríguez Guisado, Francisco | - |
crisitem.author.fullName | Andrada Borzollino, Marisa Ana | - |
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