Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/43063
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dc.contributor.authorHenríquez-Hernández, Luis A.
dc.contributor.authorLuzardo, Octavio P.
dc.contributor.authorAlmeida-González, Maira
dc.contributor.authorÁlvarez-León, Eva E.
dc.contributor.authorSerra-Majem, Lluis
dc.contributor.authorZumbado, Manuel
dc.contributor.authorBoada, Luis D.
dc.contributor.otherZumbado, Manuel
dc.contributor.otherDominguez-Boada, Luis
dc.contributor.otherAlmeida Gonzalez, Maira
dc.contributor.otherP. Luzardo, Octavio
dc.contributor.otherHenriquez-Hernandez, Luis Alberto
dc.contributor.otherSerra-Majem, Lluis
dc.date.accessioned2018-11-21T12:19:05Z-
dc.date.available2018-11-21T12:19:05Z-
dc.date.issued2011
dc.identifier.issn0013-9351
dc.identifier.urihttp://hdl.handle.net/10553/43063-
dc.description.abstractPolychlorinated biphenyls (PCBs) are persistent and toxic compounds that have been detected in human serum or tissues worldwide. The objective of our study was to determine serum PCB levels in a representative sample of the general population of the Spanish Archipelago of the Canary Islands (607 serum samples from subjects aged between 6 and 75 years) in order to establish the main causes of this contamination and to evaluate the potential risks posed by these chemicals on the population through the use of toxicity equivalence to dioxins (TEQs). PCB congeners (28, 52, 77, 81, 101, 105, 114, 118, 123, 126, 138, 153, 156, 157, 167, 169, 180, and 189) were measured by gas chromatography-mass spectrometry (GC/MS). Our results showed that PCB residues were found in 76% of serum samples analyzed, with the congeners 153 and 180 being the most frequently detected and having the highest median values (21.8 and 6.7 ng/g lipid, respectively). Serum levels of non-dioxin-like PCBs increased with age, body mass index (BMI), urban habitat, and smoking. The median concentration of the sum of PCBs considered as markers of environmental contamination by these chemicals (M-PCBs) was 46.4 ng/g lipid. Levels of the sum of dioxin-like PCBs (DL-PCBs) were 48.5 ng/g lipid in the 95th percentile, and were also positively associated with age. As a consequence, age seemed to be positively associated with TEQs levels, reaching values as high as 58.6 pg/g lipid in the serum samples from oldest people. Our results indicate that the inhabitants of the Canary Archipelago show levels of PCB contamination lower than other populations present on the Spanish mainland, as well as many populations from developed countries. Nevertheless, as these compounds may induce adverse health effects even at very low doses, our findings should be considered by local Public Health authorities in order to establish measures for diminishing the exposure of the population of these islands to PCBs. (C) 2010 Elsevier Inc. All rights reserved.
dc.publisher0013-9351
dc.relation.ispartofEnvironmental research (New York, N.Y. Print)
dc.sourceEnvironmental Research[ISSN 0013-9351],v. 111, p. 10-16
dc.subject.otherToxic Equivalency Factors
dc.subject.otherOrganochlorine Pesticides
dc.subject.otherSerum Concentrations
dc.subject.otherDibenzofurans Pcdfs
dc.subject.otherOlder Residents
dc.subject.otherDioxins Pcdds
dc.subject.otherHuman Health
dc.subject.otherPcbs
dc.subject.otherExposure
dc.subject.otherWomen
dc.titleBackground levels of polychlorinated biphenyls in the population of the Canary Islands (Spain)
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.doi10.1016/j.envres.2010.11.005
dc.identifier.scopus78751585143-
dc.identifier.isi000286715300002
dcterms.isPartOfEnvironmental Research
dcterms.sourceEnvironmental Research[ISSN 0013-9351],v. 111 (1), p. 10-16
dc.contributor.authorscopusid15829708200
dc.contributor.authorscopusid6507534124
dc.contributor.authorscopusid36450107800
dc.contributor.authorscopusid6603324897
dc.contributor.authorscopusid35596972100
dc.contributor.authorscopusid6603459604
dc.contributor.authorscopusid6603916807
dc.description.lastpage16
dc.description.firstpage10
dc.relation.volume111
dc.type2Artículoes
dc.identifier.wosWOS:000286715300002
dc.contributor.daisngid465624
dc.contributor.daisngid418704
dc.contributor.daisngid1343269
dc.contributor.daisngid1848250
dc.contributor.daisngid28836
dc.contributor.daisngid418822
dc.contributor.daisngid697526
dc.identifier.investigatorRIDB-4495-2010
dc.identifier.investigatorRIDL-5577-2015
dc.identifier.investigatorRIDNo ID
dc.identifier.investigatorRIDNo ID
dc.identifier.investigatorRIDNo ID
dc.identifier.investigatorRIDNo ID
dc.contributor.wosstandardWOS:Henriquez-Hernandez, LA
dc.contributor.wosstandardWOS:Luzardo, OP
dc.contributor.wosstandardWOS:Almeida-Gonzalez, M
dc.contributor.wosstandardWOS:Alvarez-Leon, EE
dc.contributor.wosstandardWOS:Serra-Majem, L
dc.contributor.wosstandardWOS:Zumbado, M
dc.contributor.wosstandardWOS:Boada, LD
dc.date.coverdateEnero 2011
dc.identifier.ulpgces
dc.description.sjr1,696
dc.description.jcr3,398
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptMedio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptCiencias Clínicas-
crisitem.author.deptMedio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptCiencias Clínicas-
crisitem.author.deptMedio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptCiencias Clínicas-
crisitem.author.deptNutrición-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptCiencias Clínicas-
crisitem.author.deptMedio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptCiencias Clínicas-
crisitem.author.deptMedio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptCiencias Clínicas-
crisitem.author.orcid0000-0003-3237-0316-
crisitem.author.orcid0000-0002-4153-3028-
crisitem.author.orcid0000-0003-2410-4659-
crisitem.author.orcid0000-0002-9658-9061-
crisitem.author.orcid0000-0002-1534-7758-
crisitem.author.orcid0000-0002-0195-4565-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameHenríquez Hernández, Luis Alberto-
crisitem.author.fullNamePérez Luzardo, Octavio Luis-
crisitem.author.fullNameAlmeida González, Maira Del Pino-
crisitem.author.fullNameSerra Majem, Luis-
crisitem.author.fullNameZumbado Peña, Manuel Luis-
crisitem.author.fullNameDomínguez Boada, Luis María-
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