Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/42434
DC FieldValueLanguage
dc.contributor.authorMenéndez, Rosarioen_US
dc.contributor.authorMontull, Beatrizen_US
dc.contributor.authorReyes, Soledaden_US
dc.contributor.authorAmara-Elori, Isabelen_US
dc.contributor.authorZalacain, Rafaelen_US
dc.contributor.authorCapelastegui, Albertoen_US
dc.contributor.authorAspa, Javieren_US
dc.contributor.authorBorderías, Luisen_US
dc.contributor.authorMartín-Villasclaras, Juan J.en_US
dc.contributor.authorBello, Salvadoren_US
dc.contributor.authorAlfageme, Inmaculadaen_US
dc.contributor.authorRodríguez de Castro, Felipeen_US
dc.contributor.authorRello, Jordien_US
dc.contributor.authorMolinos, Luisen_US
dc.contributor.authorRuiz-Manzano, Juanen_US
dc.contributor.authorTorres, Antonien_US
dc.date.accessioned2018-11-13T13:18:19Z-
dc.date.available2018-11-13T13:18:19Z-
dc.date.issued2016en_US
dc.identifier.issn0163-4453en_US
dc.identifier.urihttp://hdl.handle.net/10553/42434-
dc.description.abstractCommunity-acquired pneumonia (CAP) is a serious infection that may occasionally rapidly evolve provoking organ dysfunctions. We aimed to characterize CAP presenting with organ dysfunctions at the emergency room, with regard to host factors and causative microorganisms, and its impact on 30-day mortality. 460 of 4070 (11.3%) CAP patients had ≥2 dysfunctions at diagnosis, with a 30-day mortality of 12.4% vs. 3.4% in those with one or no dysfunctions. Among them, the most frequent causative microorganisms were Streptococcus pneumoniae, gram-negatives and polymicrobial etiology. Independent host risk factors for presenting with ≥2 dysfunctions were: liver (OR 2.97) and renal diseases (OR 3.91), neurological disorders (OR 1.86), and COPD (OR 1.30). Methicillin-resistant Staphylococcus aureus (OR 6.41) and bacteraemic episodes (OR 1.68) had the higher independent risk among microorganisms. The number of organ dysfunctions vs. none increased at 30-day mortality: three organs (OR 11.73), two organs (OR 4.29), and one organ (OR 2.42) whereas Enterobacteria (OR 3.73) were also independently related to mortality. The number of organ dysfunctions was the strongest 30-day mortality risk factor while Enterobacteriaceae was also associated with poorer outcome. The assessment of organ dysfunctions in CAP should be implemented for management, allocation and treatment decisions on initial evaluation.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Infectionen_US
dc.sourceJournal of Infection [ISSN 0163-4453], v. 73 (5), p. 419-426en_US
dc.subject320508 Enfermedades pulmonaresen_US
dc.subject32 Ciencias médicasen_US
dc.subject.otherCommunity-acquired pneumoniaen_US
dc.subject.otherComorbidityen_US
dc.subject.otherMortalityen_US
dc.subject.otherOrgan dysfunctionen_US
dc.subject.otherRisk factorsen_US
dc.titlePneumonia presenting with organ dysfunctions: Causative microorganisms, host factors and outcomeen_US
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.doi10.1016/j.jinf.2016.08.001
dc.identifier.scopus84992709209-
dc.identifier.isi000393123100003
dc.contributor.authorscopusid7102205716
dc.contributor.authorscopusid54409259200
dc.contributor.authorscopusid7005577703
dc.contributor.authorscopusid57191543564
dc.contributor.authorscopusid7003514650
dc.contributor.authorscopusid55886745800
dc.contributor.authorscopusid6602555827
dc.contributor.authorscopusid16168865800
dc.contributor.authorscopusid6506770332
dc.contributor.authorscopusid7004458552
dc.contributor.authorscopusid6602891624
dc.contributor.authorscopusid55942667000
dc.contributor.authorscopusid7102682070
dc.contributor.authorscopusid6603804487
dc.contributor.authorscopusid7003705264
dc.contributor.authorscopusid56714659000
dc.description.lastpage426-
dc.identifier.issue5-
dc.description.firstpage419-
dc.relation.volume73-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid87272
dc.contributor.daisngid1886154
dc.contributor.daisngid1483817
dc.contributor.daisngid6725930
dc.contributor.daisngid709164
dc.contributor.daisngid471608
dc.contributor.daisngid952601
dc.contributor.daisngid857548
dc.contributor.daisngid3466293
dc.contributor.daisngid1667187
dc.contributor.daisngid1182656
dc.contributor.daisngid464249
dc.contributor.daisngid15178
dc.contributor.daisngid1228919
dc.contributor.daisngid427818
dc.contributor.daisngid50528
dc.contributor.wosstandardWOS:Menendez, R
dc.contributor.wosstandardWOS:Montull, B
dc.contributor.wosstandardWOS:Reyes, S
dc.contributor.wosstandardWOS:Amara-Elori, I
dc.contributor.wosstandardWOS:Zalacain, R
dc.contributor.wosstandardWOS:Capelastegui, A
dc.contributor.wosstandardWOS:Aspa, J
dc.contributor.wosstandardWOS:Borderias, L
dc.contributor.wosstandardWOS:Martin-Villasclaras, JJ
dc.contributor.wosstandardWOS:Bello, S
dc.contributor.wosstandardWOS:Alfageme, I
dc.contributor.wosstandardWOS:de Castro, FR
dc.contributor.wosstandardWOS:Rello, J
dc.contributor.wosstandardWOS:Molinos, L
dc.contributor.wosstandardWOS:Ruiz-Manzano, J
dc.contributor.wosstandardWOS:Torres, A
dc.date.coverdateNoviembre 2016
dc.identifier.ulpgces
dc.description.sjr2,014
dc.description.jcr4,201
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUIBS: Patología médica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-6812-2739-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameRodríguez De Castro, Felipe Carlos B.-
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