Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/41858
Campo DC Valoridioma
dc.contributor.authorVilar, José M.en_US
dc.contributor.authorManera, Maria E.en_US
dc.contributor.authorSantana, Angeloen_US
dc.contributor.authorSpinella, Giuseppeen_US
dc.contributor.authorRodríguez Lozano, David Oliverioen_US
dc.contributor.authorRubio, Mónicaen_US
dc.contributor.authorCarrillo, José M.en_US
dc.contributor.authorSopena, Joaquínen_US
dc.contributor.authorBatista, Miguelen_US
dc.date.accessioned2018-09-05T09:43:17Z-
dc.date.available2018-09-05T09:43:17Z-
dc.date.issued2018en_US
dc.identifier.issn1932-6203en_US
dc.identifier.urihttp://hdl.handle.net/10553/41858-
dc.description.abstractThe goal of this study was to objectively assess the effect of a platelet-rich plasma (PRP) derivate in English bulldogs with stifle degenerative joint disease secondary to cranial cruciate ligament rupture (CCLR). We used a force platform and affixed electrogoniometers to measure peak vertical force (PVF), vertical impulse (VI), stance time (ST), and angular range of motion (AROM), from 12 lame client-owned English bulldogs with post-CCLR stifle joint abnormalities. The 12 affected subjects were treated with 4 intra-articular injections of PRP, at 30-day intervals. Ten untreated, sound English bulldogs were used as a reference group. Clinical outcomes were evaluated using a linear mixed effects model. Mean values of PVF, VI, ST, and AROM were improved within the first 3 months post-treatment in the CCLR group, with mean measured changes increasing to maximum 4.56% body weight gain, 1.5% body weight/second, 0.07 seconds, and 6.18 degrees, respectively. The effects declined progressively after the treatment interval, ending at nearly initial levels after 6 months. This study demonstrates that dogs with CCLR treated with intra-articular PRP had improved PVF, VI, ST, and AROM over time; the duration of effect was waning by the end of the post-treatment period.en_US
dc.languageengen_US
dc.relation.ispartofPLoS ONEen_US
dc.sourcePLoS ONE [ISSN 1932-6203], v. 13 (3)en_US
dc.subject3109 Ciencias veterinariasen_US
dc.subject120903 Análisis de datosen_US
dc.subject240401 Bioestadísticaen_US
dc.subject.otherDogs
dc.subject.otherDeficiency
dc.subject.otherEfficacy
dc.subject.otherTherapy
dc.subject.otherDisease
dc.subject.otherForce
dc.subject.otherKnee
dc.subject.otherTendinopathy
dc.subject.otherInjections
dc.subject.otherSurgery
dc.titleEffect of leukocyte-reduced platelet-rich plasma on osteoarthritis caused by cranial cruciate ligament rupture: A canine gait analysis modelen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1371/journal.pone.0194752en_US
dc.identifier.scopus85044230301-
dc.identifier.isi000427796800053-
dc.contributor.authorscopusid7005533720-
dc.contributor.authorscopusid57193057577-
dc.contributor.authorscopusid56554207500-
dc.contributor.authorscopusid6602842395-
dc.contributor.authorscopusid57201296152-
dc.contributor.authorscopusid9532488300-
dc.contributor.authorscopusid37071989800-
dc.contributor.authorscopusid9534772600-
dc.contributor.authorscopusid57212844863-
dc.identifier.issue3-
dc.relation.volume13en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid913655-
dc.contributor.daisngid9095077-
dc.contributor.daisngid4213964-
dc.contributor.daisngid1106016-
dc.contributor.daisngid9852733-
dc.contributor.daisngid1882833-
dc.contributor.daisngid30324417-
dc.contributor.daisngid2284901-
dc.contributor.daisngid3097430-
dc.identifier.externalWOS:000427796800053-
dc.contributor.wosstandardWOS:Vilar, JM-
dc.contributor.wosstandardWOS:Manera, ME-
dc.contributor.wosstandardWOS:Santana, A-
dc.contributor.wosstandardWOS:Spinella, G-
dc.contributor.wosstandardWOS:Rodriguez, O-
dc.contributor.wosstandardWOS:Rubio, M-
dc.contributor.wosstandardWOS:Carrillo, JM-
dc.contributor.wosstandardWOS:Sopena, J-
dc.contributor.wosstandardWOS:Batista, M-
dc.date.coverdateMarzo 2018en_US
dc.identifier.ulpgces
dc.description.sjr1,1
dc.description.jcr2,776
dc.description.sjrqQ1
dc.description.jcrqQ2
dc.description.scieSCIE
dc.description.erihplusERIH PLUS
item.fulltextCon texto completo-
item.grantfulltextopen-
crisitem.author.deptGIR IUIBS: Medicina Veterinaria e Investigación Terapéutica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR Estadística-
crisitem.author.deptDepartamento de Matemáticas-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR IUIBS: Medicina Veterinaria e Investigación Terapéutica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.orcid0000-0002-2060-2274-
crisitem.author.orcid0000-0002-6513-4814-
crisitem.author.orcid0000-0003-4040-1266-
crisitem.author.orcid0000-0001-9753-4786-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgDepartamento de Matemáticas-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameVilar Guereño, José Manuel-
crisitem.author.fullNameSantana Del Pino, Ángelo-
crisitem.author.fullNameRodríguez Lozano, David Oliverio-
crisitem.author.fullNameBatista Arteaga, Miguel-
Colección:Artículos
miniatura
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