Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/40297
DC FieldValueLanguage
dc.contributor.authorHenríquez Hernández, Luis Alberto-
dc.contributor.authorCarretón, Elena-
dc.contributor.authorCamacho Rodríguez, María-
dc.contributor.authorMontoya-Alonso, JA-
dc.contributor.authorBoada, luis d-
dc.contributor.authorFernández Valerón, Pilar-
dc.contributor.authorFalcón-Cordón, Y-
dc.contributor.authorFalcón-Cordón, S.-
dc.contributor.authorAlmeida-González, Maira-
dc.contributor.authorZumbado, Manuel-
dc.contributor.authorPérez Luzardo, Octavio L-
dc.contributor.otherCAMACHO, MARIA-
dc.contributor.otherZumbado, Manuel-
dc.contributor.otherMontoya-Alonso, Jose Alberto-
dc.date.accessioned2018-06-11T09:41:35Z-
dc.date.available2018-06-11T09:41:35Z-
dc.date.issued2017-
dc.identifier.issn0048-9697-
dc.identifier.urihttp://hdl.handle.net/10553/40297-
dc.description.abstractIt has been described that the co-existence of parasite infection and chemical exposure has various effects on the accumulation of persistent organochlorine pollutants (POPs) in the host. Certain parasites are not only able to accumulate POPs but also seem to have the ability to metabolize certain compounds. We have designed a case–control study aimed to disclose the role of Dirofilaria immitis in the bioavailability of POPs in dogs trying to know whether these parasites store or metabolize the POPs. A total of 40 common POPs (18 polychlorinated biphenyls congeners (PCBs) and 22 organochlorine pesticides were quantified in dog serum. The study included three groups of dogs prospectively recruited in the island of Gran Canaria (Canary Islands, Spain): a) control animals, non-parasitized (serologically tested negative, n = 24); b) a group constituted by dogs tested positive for heartworm disease (D. immitis) and negative for other parasites (n = 25); and c) the same group of parasitized dogs after the treatment against the parasite (n = 25). The presence of D. immitis was strongly associated with lower serum levels of a wide range of pollutant in their hosts (PCB congeners 28, 105, 118, 123, 138, 153, 167 and 180; hexachlorobenzene, lindane, aldrin, dieldrin, and methoxychlor). The serum levels of these substances remained at very low levels after the treatment against the parasite, suggesting that D. immitis do not simply store such compounds, but they probably have some ability to metabolize these pollutants. We encourage the use of the parasite infestation status as a cofactor that needs to be taken into account in studies aimed to evaluate the serum levels of POPs.-
dc.languageeng-
dc.publisher0048-9697-
dc.relation.ispartofScience of the Total Environment-
dc.sourceScience of the Total Environment [ISSN 0048-9697], v. 575, p. 1445-1452-
dc.subject3109 Ciencias veterinarias-
dc.subject.otherCanines-
dc.subject.otherDirofilariasis-
dc.subject.otherHost–parasite interactions-
dc.subject.otherOrganochlorine pesticides-
dc.subject.otherPolychlorinated biphenyls-
dc.titleThe heartworm (Dirofilaria immitis) seems to be able to metabolize organochlorine pesticides and polychlorinated biphenyls: A case–control study in dogs-
dc.typeinfo:eu-repo/semantics/Article-
dc.typeArticlees
dc.identifier.doi10.1016/j.scitotenv.2016.09.236
dc.identifier.scopus84991261215-
dc.identifier.isi000390373400145-
dcterms.isPartOfScience Of The Total Environment-
dcterms.sourceScience Of The Total Environment[ISSN 0048-9697],v. 575, p. 1445-1452-
dc.contributor.authorscopusid15829708200
dc.contributor.authorscopusid36143929200
dc.contributor.authorscopusid34067495700
dc.contributor.authorscopusid6504331949
dc.contributor.authorscopusid6603916807
dc.contributor.authorscopusid6603469417
dc.contributor.authorscopusid57191515612
dc.contributor.authorscopusid57191516894
dc.contributor.authorscopusid36450107800
dc.contributor.authorscopusid6603459604
dc.contributor.authorscopusid6507534124
dc.description.lastpage1452-
dc.description.firstpage1445-
dc.relation.volume575-
dc.investigacionCiencias de la Salud-
dc.type2Artículo-
dc.identifier.wosWOS:000390373400145-
dc.contributor.daisngid30144524
dc.contributor.daisngid465624-
dc.contributor.daisngid1038823-
dc.contributor.daisngid711282-
dc.contributor.daisngid895593-
dc.contributor.daisngid1656886-
dc.contributor.daisngid1146740-
dc.contributor.daisngid6977981-
dc.contributor.daisngid6686626-
dc.contributor.daisngid1343269-
dc.contributor.daisngid418822-
dc.contributor.daisngid418704-
dc.identifier.investigatorRIDH-5085-2015-
dc.identifier.investigatorRIDB-4495-2010-
dc.identifier.investigatorRIDNo ID-
dc.contributor.wosstandardWOS:Henriquez-Hernandez, LA
dc.contributor.wosstandardWOS:Carreton, E
dc.contributor.wosstandardWOS:Camacho, M
dc.contributor.wosstandardWOS:Montoya-Alonso, JA
dc.contributor.wosstandardWOS:Boada, LD
dc.contributor.wosstandardWOS:Valeron, PF
dc.contributor.wosstandardWOS:Falcon-Cordon, Y
dc.contributor.wosstandardWOS:Falcon-Cordon, S
dc.contributor.wosstandardWOS:Almeida-Gonzalez, M
dc.contributor.wosstandardWOS:Zumbado, M
dc.contributor.wosstandardWOS:Luzardo, OP
dc.date.coverdateEnero 2017
dc.identifier.ulpgces
dc.description.sjr1,546
dc.description.jcr4,61
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Medicina Veterinaria e Investigación Terapéutica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR IUIBS: Medicina Veterinaria e Investigación Terapéutica-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Bioquímica y Biología Molecular, Fisiología, Genética e Inmunología-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR IUIBS: Medio Ambiente y Salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.orcid0000-0003-3237-0316-
crisitem.author.orcid0000-0001-6509-910X-
crisitem.author.orcid0000-0003-2891-1474-
crisitem.author.orcid0000-0002-2683-7592-
crisitem.author.orcid0000-0002-0195-4565-
crisitem.author.orcid0000-0001-5865-7003-
crisitem.author.orcid0000-0003-2410-4659-
crisitem.author.orcid0000-0002-1534-7758-
crisitem.author.orcid0000-0002-4153-3028-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameHenríquez Hernández, Luis Alberto-
crisitem.author.fullNameCarretón Gómez, Elena-
crisitem.author.fullNameCamacho Rodríguez, María De Los Ángeles-
crisitem.author.fullNameMontoya Alonso, José Alberto-
crisitem.author.fullNameDomínguez Boada, Luis María-
crisitem.author.fullNameFernández Valerón, Josefa Pilar-
crisitem.author.fullNameAlmeida González, Maira Del Pino-
crisitem.author.fullNameZumbado Peña, Manuel Luis-
crisitem.author.fullNamePérez Luzardo, Octavio Luis-
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