Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/37139
Campo DC Valoridioma
dc.contributor.authorMarrero Alemán, Gabrielen_US
dc.contributor.authorEl Habr, Constantinen_US
dc.contributor.authorIslas Norris, Dianaen_US
dc.contributor.authorMontenegro Dámaso, Tarsilaen_US
dc.contributor.authorBorrego, Leopoldoen_US
dc.contributor.authorSangueza, Omar P.en_US
dc.date.accessioned2018-05-23T11:32:09Z-
dc.date.available2018-05-23T11:32:09Z-
dc.date.issued2017en_US
dc.identifier.issn0193-1091en_US
dc.identifier.urihttp://hdl.handle.net/10553/37139-
dc.description.abstractCutaneous mastocytosis is defined by the presence of mast cells within the skin in the absence of other criteria for the diagnosis of systemic mastocytosis. Mast cells are characterized by an abundant granular cytoplasm and a round to oval or spindle-shaped nuclei. The presence of mast cells with bilobed and multilobed nuclei in cutaneous mastocytosis is a rare phenomenon and has been rarely reported in the literature. To our knowledge, there are only 4 reported cases of cutaneous mastocytosis with atypical mast cells. We hereby report a case of urticaria pigmentosa in a 7-year-old female patient. The patient presented with asymptomatic skin lesions of several years duration over the neck and left scapular area. Histopathological examination revealed the presence of middermal perivascular infiltrates mainly composed of mast cells, few lymphocytes, and eosinophils. Most mast cells showed pleomorphic nuclei with bilobed and multilobed morphology that revealed a positive expression for CD117, tryptase, CD68, and Giemsa stains. Based on these findings the diagnosis of urticaria pigmentosa with atypical mast cells was made. Additional tests to rule out systemic involvement were performed. All values, including a tryptase level, were within normal limits. No changes were noted after 1-year follow-up.en_US
dc.languageengen_US
dc.relation.ispartofAmerican Journal of Dermatopathologyen_US
dc.sourceAmerican Journal of Dermatopathology[ISSN 0193-1091],v. 39, p. 310-312en_US
dc.subject32 Ciencias médicasen_US
dc.subject.otherCutaneous mastocytosisen_US
dc.subject.otherAtypical mast cellsen_US
dc.subject.otherUrticaria pigmentosaen_US
dc.subject.otherSystemic mastocytosisen_US
dc.titleCutaneous mastocytosis with atypical mast cells in a 7-year-old girlen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeinfo:eu-repo/semantics/Articlees
dc.typeArticlees
dc.identifier.doi10.1097/DAD.0000000000000768
dc.identifier.scopus85015874113
dc.identifier.isi000398156400015-
dc.contributor.authorscopusid57193697584
dc.contributor.authorscopusid55902877900
dc.contributor.authorscopusid57198295728
dc.contributor.authorscopusid15126546600
dc.contributor.authorscopusid7004025265
dc.contributor.authorscopusid7006881260
dc.identifier.eissn1533-0311-
dc.description.lastpage312-
dc.identifier.issue4-
dc.description.firstpage310-
dc.relation.volume39-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid5459190
dc.contributor.daisngid5112945
dc.contributor.daisngid3918872
dc.contributor.daisngid7918877
dc.contributor.daisngid6293174
dc.contributor.daisngid140278
dc.contributor.wosstandardWOS:Aleman, GM
dc.contributor.wosstandardWOS:El Habr, C
dc.contributor.wosstandardWOS:Norris, DI
dc.contributor.wosstandardWOS:Damaso, TM
dc.contributor.wosstandardWOS:Borrego, L
dc.contributor.wosstandardWOS:Sangueza, OP
dc.date.coverdateAbril 2017
dc.identifier.ulpgces
dc.description.sjr0,6
dc.description.jcr1,21
dc.description.sjrqQ2
dc.description.jcrqQ4
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-0199-2756-
crisitem.author.fullNameBorrego Hernando, Leopoldo-
Colección:Artículos
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