Please use this identifier to cite or link to this item: https://accedacris.ulpgc.es/handle/10553/35450
DC FieldValueLanguage
dc.contributor.authorGutierrez-Bedmar, Marioen_US
dc.contributor.authorMartínez-González, Miguel Ángelen_US
dc.contributor.authorMuñoz-Bravo, Carlosen_US
dc.contributor.authorRuiz-Canela, Miguelen_US
dc.contributor.authorMariscal, Albertoen_US
dc.contributor.authorSalas-Salvadó, Jordien_US
dc.contributor.authorEstruch, Ramónen_US
dc.contributor.authorCorella, Doloresen_US
dc.contributor.authorArós, Fernandoen_US
dc.contributor.authorFitó, Montseen_US
dc.contributor.authorLapetra, Joséen_US
dc.contributor.authorSerra-Majem, Lluisen_US
dc.contributor.authorPinto, Xavieren_US
dc.contributor.authorAlonso-Gómez, A.en_US
dc.contributor.authorPortolés, O.en_US
dc.contributor.authorFiol, Miquelen_US
dc.contributor.authorBulló, Mónicaen_US
dc.contributor.authorCastaner, Olgaen_US
dc.contributor.authorRos, Emilioen_US
dc.contributor.authorGómez-Gracia, Enriqueen_US
dc.date.accessioned2018-04-19T09:57:26Z-
dc.date.available2018-04-19T09:57:26Z-
dc.date.issued2017en_US
dc.identifier.issn1346-9843en_US
dc.identifier.urihttps://accedacris.ulpgc.es/handle/10553/35450-
dc.description.abstractBackground: Epidemiological data on chromium (Cr) exposure and the risk of cardiovascular disease (CVD) are still limited. Toenail Cr level (TCL) provides a time-integrated measure reflecting long-term Cr exposure. We measured TCL to assess the hypothesis that long-term Cr exposure was inversely associated with incident CVD in a population at high risk for CVD. Methods and Results: The associations between TCL and CVD were evaluated in a case-control study nested within the "PREvencion con Dleta MEDiterranea" (PREDIMED) trial. We randomly selected 147 of the 288 patients diagnosed with CVD during follow-up and matched them on age and sex to 271 controls. Instrumental neutron activation analysis was used to assess TCL. In-person interviews, medical record reviews, and validated questionnaires were used to assess covariates. The fully adjusted OR for the highest vs. lowest quartile of toenail Cr was 0.54 (95% CI: 0.26-1.14; P-trend=0.189) for the nested case-control study. On stratification for diabetes mellitus (DM), OR was 1.37 (95% CI: 0.54-3.46; P-trend=0.364) for the DM group, and 0.25 (95% CI: 0.08-0.80; P-trend=0.030) for the non-DM group (P for interaction=0.078). Conclusions: The present findings, although not statistically significant, are consistent with previously reported inverse associations between TCL and CVD. These results, especially for non-DM patients, increase the limited epidemiological knowledge about the possible protective role of Cr against CVD.en_US
dc.languageengen_US
dc.relation.ispartofCirculation Journalen_US
dc.sourceCirculation Journal [ISSN 1346-9843], v. 81 (8), p. 1183-1190en_US
dc.subject3206 Ciencias de la nutriciónen_US
dc.subject.otherCardiovascular diseaseen_US
dc.subject.otherChromiumen_US
dc.subject.otherDiabetesen_US
dc.subject.otherPREDIMEDen_US
dc.subject.otherToenail biomarkeren_US
dc.titleChromium exposure and risk of cardiovascular disease in high cardiovascular risk subjects: Nested case-control study in the prevention with mediterranean diet (PREDIMED) studyen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1253/circj.CJ-17-0032en_US
dc.identifier.scopus85025804076-
dc.identifier.isi000408462800019-
dc.contributor.authorscopusid6506505275-
dc.contributor.authorscopusid7004290629-
dc.contributor.authorscopusid35201757300-
dc.contributor.authorscopusid6603417884-
dc.contributor.authorscopusid55811878600-
dc.contributor.authorscopusid7003357665-
dc.contributor.authorscopusid7005989830-
dc.contributor.authorscopusid7003570538-
dc.contributor.authorscopusid7004158382-
dc.contributor.authorscopusid6602891390-
dc.contributor.authorscopusid6507771144-
dc.contributor.authorscopusid57202560799-
dc.contributor.authorscopusid7004430064-
dc.contributor.authorscopusid7004308784-
dc.contributor.authorscopusid6603006074-
dc.contributor.authorscopusid7005315313-
dc.contributor.authorscopusid57194127916-
dc.contributor.authorscopusid36487707800-
dc.contributor.authorscopusid57202569537-
dc.contributor.authorscopusid57202571697-
dc.identifier.eissn1347-4820-
dc.identifier.issue8-
dc.relation.volume81en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid1572264-
dc.contributor.daisngid17754-
dc.contributor.daisngid4082099-
dc.contributor.daisngid31761100-
dc.contributor.daisngid1728881-
dc.contributor.daisngid25605-
dc.contributor.daisngid19357-
dc.contributor.daisngid25404-
dc.contributor.daisngid106289-
dc.contributor.daisngid20323289-
dc.contributor.daisngid34937322-
dc.contributor.daisngid28836-
dc.contributor.daisngid115192-
dc.contributor.daisngid28220288-
dc.contributor.daisngid29053254-
dc.contributor.daisngid78038-
dc.contributor.daisngid167315-
dc.contributor.daisngid1104985-
dc.contributor.daisngid23007-
dc.contributor.daisngid276771-
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Gutierrez-Bedmar, M-
dc.contributor.wosstandardWOS:Martinez-Gonzalez, MA-
dc.contributor.wosstandardWOS:Munoz-Bravo, C-
dc.contributor.wosstandardWOS:Ruiz-Canela, M-
dc.contributor.wosstandardWOS:Mariscal, A-
dc.contributor.wosstandardWOS:Salas-Salvado, J-
dc.contributor.wosstandardWOS:Estruch, R-
dc.contributor.wosstandardWOS:Corella, D-
dc.contributor.wosstandardWOS:Aros, F-
dc.contributor.wosstandardWOS:Fito, M-
dc.contributor.wosstandardWOS:Lapetra, J-
dc.contributor.wosstandardWOS:Serra-Majem, L-
dc.contributor.wosstandardWOS:Pinto, X-
dc.contributor.wosstandardWOS:Alonso-Gomez, A-
dc.contributor.wosstandardWOS:Portoles, O-
dc.contributor.wosstandardWOS:Fiol, M-
dc.contributor.wosstandardWOS:Bullo, M-
dc.contributor.wosstandardWOS:Castaner, O-
dc.contributor.wosstandardWOS:Ros, E-
dc.contributor.wosstandardWOS:Gomez-Gracia, E-
dc.date.coverdateEnero 2017en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr1,4
dc.description.jcr2,895
dc.description.sjrqQ1
dc.description.jcrqQ2
dc.description.scieSCIE
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptGIR IUIBS: Nutrición-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.orcid0000-0002-9658-9061-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameSerra Majem, Luis-
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