Healthcare Professionals' Experience with Oral Oligomeric Supplements in Malnourished Patients in Spain: S-QUEST Study

Abstract

Background and aim: malnutrition, caused by malabsorption and maldigestion, affects nutrient intake and utilization. Early detection and interventions, such as oligomeric enteral formulas, are key to improving outcomes. This study explored healthcare professionals’ experiences with oligomeric supplements in Spain’s public healthcare system, focusing on clinical practices, patient adherence, tolerability, and benefits. Methods: the S-QUEST study was an observational, multicenter, cross-sectional investigation conducted in real-world clinical settings. Healthcare providers, mainly physicians from various specialties, were surveyed electronically using an ad hoc questionnaire on nutritional screening practices for malnourished patients prescribed oligomeric supplements. Data were analyzed using SPSS® (version 25.0), with significance set at p < 0.05. Results: a total of 259 healthcare providers from 41 Spanish hospitals completed the survey. Nutritional screening was reportedly performed by 75 % of respondents, with endocrinologists and gastroenterologists indicating more frequent use (p < 0.001) and a broader range of methods. Oligomeric formulas were prescribed by 67.6 % of participants, mainly in cases involving oncology, inflammatory bowel disease, and diarrhea-related malnutrition. A self-reported adherence rate of 85 % was noted, with higher compliance perceived by endocrinologists and gastroenterologists. Additionally, 95 %ofparticipants perceived oligomeric formulas as beneficial, particularly in relation to weight, stool consistency, and albumin levels. Conclusions: this study explored healthcare providers’ perceptions of oligomeric formulas in malnutrition management. Respondents, particularly endocrinologists and gastroenterologists, reported frequent use and perceived patient benefits. High selfreported adherence suggests good acceptance. Further research is needed to objectively assess outcomes and guide clinical practice and training.