Successful management of canine (canis lupus familiaris) mandibular osteolytic chondroma with electrochemotherapy

Abstract

In recent years, electrochemotherapy has gained relevance in veterinary oncology for the treatment of locally invasive superficial tumours in dogs, such as mast cell tumours, perianal neoplasms, soft tissue sarcomas, oral squamous cell carcinomas and melanomas. Although chondromas are generally benign, their progressive growth can cause significant anatomical and functional impairments. When located in the mandible, traditional treatment often involves rostral mandiblectomy, which may lead to postoperative sequelae, affecting the animal's quality of life. In this case, electrochemotherapy with bleomycin was well tolerated and achieved effective local tumour control with a single session, without the need for invasive surgery. To the best of our knowledge, this is the first clinical report describing the successful use of electrochemotherapy as a sole therapy for a mandibular chondroma in a dog. This study aimed to explore electrochemotherapy as a less invasive alternative for managing this tumour.