Identificador persistente para citar o vincular este elemento:
https://accedacris.ulpgc.es/handle/10553/139757
Campo DC | Valor | idioma |
---|---|---|
dc.contributor.author | Stuckey, Ruth | en_US |
dc.contributor.author | Navarrete Bullon, Laura | en_US |
dc.contributor.author | Borrero Borrego, Asuncion | en_US |
dc.contributor.author | Ballester, Violeta Vidal | en_US |
dc.contributor.author | Rodriguez-Medina, Carlos | en_US |
dc.contributor.author | Morales Curbelo, Alejandro | en_US |
dc.contributor.author | Gonzalez Pinedo, Leslie | en_US |
dc.contributor.author | Torres Ochando, Melissa | en_US |
dc.contributor.author | Veiga Vaz, Alvaro | en_US |
dc.contributor.author | Perera, Maria del Mar | en_US |
dc.contributor.author | Bilbao Sieyro, Cristina | en_US |
dc.contributor.author | López Rodríguez, Juan Francisco | en_US |
dc.contributor.author | Segura Díaz, Adrian | en_US |
dc.contributor.author | Gómez Casares, María Teresa | en_US |
dc.date.accessioned | 2025-06-09T15:17:54Z | - |
dc.date.available | 2025-06-09T15:17:54Z | - |
dc.date.issued | 2025 | en_US |
dc.identifier.issn | 0939-5555 | en_US |
dc.identifier.other | WoS | - |
dc.identifier.other | Scopus | - |
dc.identifier.uri | https://accedacris.ulpgc.es/handle/10553/139757 | - |
dc.description.abstract | This case highlights a young CML patient who achieved a major molecular response (MMR) after just four months with a subtherapeutic dose of asciminib. The patient could not tolerate full-dose asciminib, or the full dose of two previous tyrosine kinase inhibitors (TKI) due to myelotoxicity, but blood counts recovered rapidly upon TKI suspension and reduced dosing enabled sustained treatment. This is the second reported case of the use of 20 mg QD asciminib, four times below the recommended dose, and the first to demonstrate efficacy at this dose. The study emphasizes asciminib's potential for overcoming treatment challenges associated with multi-resistant/intolerant CML patients. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Annals of Hematology | en_US |
dc.source | Annals Of Hematology[ISSN 0939-5555], v. 104, pp. 3007-3009 (Abril 2025) | en_US |
dc.subject | 32 Ciencias médicas | en_US |
dc.subject | 3209 Farmacología | en_US |
dc.subject | 320708 Hematología | en_US |
dc.subject.other | Asciminib | en_US |
dc.subject.other | Tyrosine Kinase Inhibitors (Tkis) | en_US |
dc.subject.other | Cytopenia | en_US |
dc.subject.other | Subtherapeutic Dosing | en_US |
dc.title | Molecular response with asciminib 20 mg QD in a patient intolerant to multiple TKIs | en_US |
dc.type | info:eu-repo/semantics/Article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.1007/s00277-025-06339-5 | en_US |
dc.identifier.scopus | 105002164409 | - |
dc.identifier.isi | 001461146000001 | - |
dc.contributor.orcid | 0000-0001-6955-2290 | - |
dc.contributor.orcid | NO DATA | - |
dc.contributor.orcid | 0000-0002-0293-5614 | - |
dc.contributor.orcid | NO DATA | - |
dc.contributor.orcid | NO DATA | - |
dc.contributor.orcid | NO DATA | - |
dc.contributor.orcid | NO DATA | - |
dc.contributor.orcid | 0000-0001-5465-3355 | - |
dc.contributor.orcid | NO DATA | - |
dc.contributor.orcid | 0009-0006-9649-4050 | - |
dc.contributor.orcid | 0000-0002-4796-1445 | - |
dc.contributor.orcid | 0000-0002-4862-4088 | - |
dc.contributor.orcid | 0000-0002-2070-3227 | - |
dc.contributor.orcid | 0000-0003-0505-5126 | - |
dc.contributor.authorscopusid | 8940351300 | - |
dc.contributor.authorscopusid | 57902847700 | - |
dc.contributor.authorscopusid | 58658262000 | - |
dc.contributor.authorscopusid | 59728064800 | - |
dc.contributor.authorscopusid | 55482691500 | - |
dc.contributor.authorscopusid | 59727686200 | - |
dc.contributor.authorscopusid | 55912748500 | - |
dc.contributor.authorscopusid | 57550315700 | - |
dc.contributor.authorscopusid | 57902217400 | - |
dc.contributor.authorscopusid | 7005775092 | - |
dc.contributor.authorscopusid | 12759635600 | - |
dc.contributor.authorscopusid | 58355791500 | - |
dc.contributor.authorscopusid | 57216532422 | - |
dc.contributor.authorscopusid | 6602513846 | - |
dc.identifier.eissn | 1432-0584 | - |
dc.description.lastpage | 3009 | en_US |
dc.description.firstpage | 3007 | en_US |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.contributor.daisngid | 616098 | - |
dc.contributor.daisngid | 19596908 | - |
dc.contributor.daisngid | 19473036 | - |
dc.contributor.daisngid | 72969968 | - |
dc.contributor.daisngid | 49909292 | - |
dc.contributor.daisngid | 6543176 | - |
dc.contributor.daisngid | 13756377 | - |
dc.contributor.daisngid | 26054558 | - |
dc.contributor.daisngid | 73031682 | - |
dc.contributor.daisngid | 13569576 | - |
dc.contributor.daisngid | 2469898 | - |
dc.contributor.daisngid | 54706386 | - |
dc.contributor.daisngid | 13982043 | - |
dc.contributor.daisngid | 2469900 | - |
dc.description.numberofpages | 3 | en_US |
dc.utils.revision | Sí | en_US |
dc.contributor.wosstandard | WOS:Stuckey, R | - |
dc.contributor.wosstandard | WOS:Bullón, LN | - |
dc.contributor.wosstandard | WOS:Borrego, AB | - |
dc.contributor.wosstandard | WOS:Ballester, VV | - |
dc.contributor.wosstandard | WOS:Rodríguez-Medina, C | - |
dc.contributor.wosstandard | WOS:Curbelo, AM | - |
dc.contributor.wosstandard | WOS:Pinedo, LG | - |
dc.contributor.wosstandard | WOS:Ochando, MT | - |
dc.contributor.wosstandard | WOS:Vaz, AV | - |
dc.contributor.wosstandard | WOS:Perera, MD | - |
dc.contributor.wosstandard | WOS:Bilbao-Sieyro, C | - |
dc.contributor.wosstandard | WOS:Rodríguez, JFL | - |
dc.contributor.wosstandard | WOS:Segura-Díaz, A | - |
dc.contributor.wosstandard | WOS:Gómez-Casares, MT | - |
dc.date.coverdate | Abril 2025 | en_US |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-MED | en_US |
dc.description.sjr | 0,912 | |
dc.description.jcr | 3,0 | |
dc.description.sjrq | Q1 | |
dc.description.jcrq | Q2 | |
dc.description.scie | SCIE | |
dc.description.miaricds | 11,0 | |
item.fulltext | Con texto completo | - |
item.grantfulltext | open | - |
crisitem.author.dept | Departamento de Morfología | - |
crisitem.author.dept | Departamento de Ciencias Médicas y Quirúrgicas | - |
crisitem.author.orcid | 0000-0002-4796-1445 | - |
crisitem.author.orcid | 0000-0003-0505-5126 | - |
crisitem.author.fullName | Bilbao Sieyro, Cristina | - |
crisitem.author.fullName | López Rodríguez, Juan Francisco | - |
crisitem.author.fullName | Segura Díaz, Adrian | - |
crisitem.author.fullName | Gómez Casares, María Teresa | - |
Colección: | Artículos |
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