Identificador persistente para citar o vincular este elemento: https://accedacris.ulpgc.es/handle/10553/139757
Campo DC Valoridioma
dc.contributor.authorStuckey, Ruthen_US
dc.contributor.authorNavarrete Bullon, Lauraen_US
dc.contributor.authorBorrero Borrego, Asuncionen_US
dc.contributor.authorBallester, Violeta Vidalen_US
dc.contributor.authorRodriguez-Medina, Carlosen_US
dc.contributor.authorMorales Curbelo, Alejandroen_US
dc.contributor.authorGonzalez Pinedo, Leslieen_US
dc.contributor.authorTorres Ochando, Melissaen_US
dc.contributor.authorVeiga Vaz, Alvaroen_US
dc.contributor.authorPerera, Maria del Maren_US
dc.contributor.authorBilbao Sieyro, Cristinaen_US
dc.contributor.authorLópez Rodríguez, Juan Franciscoen_US
dc.contributor.authorSegura Díaz, Adrianen_US
dc.contributor.authorGómez Casares, María Teresaen_US
dc.date.accessioned2025-06-09T15:17:54Z-
dc.date.available2025-06-09T15:17:54Z-
dc.date.issued2025en_US
dc.identifier.issn0939-5555en_US
dc.identifier.otherWoS-
dc.identifier.otherScopus-
dc.identifier.urihttps://accedacris.ulpgc.es/handle/10553/139757-
dc.description.abstractThis case highlights a young CML patient who achieved a major molecular response (MMR) after just four months with a subtherapeutic dose of asciminib. The patient could not tolerate full-dose asciminib, or the full dose of two previous tyrosine kinase inhibitors (TKI) due to myelotoxicity, but blood counts recovered rapidly upon TKI suspension and reduced dosing enabled sustained treatment. This is the second reported case of the use of 20 mg QD asciminib, four times below the recommended dose, and the first to demonstrate efficacy at this dose. The study emphasizes asciminib's potential for overcoming treatment challenges associated with multi-resistant/intolerant CML patients.en_US
dc.languageengen_US
dc.relation.ispartofAnnals of Hematologyen_US
dc.sourceAnnals Of Hematology[ISSN 0939-5555], v. 104, pp. 3007-3009 (Abril 2025)en_US
dc.subject32 Ciencias médicasen_US
dc.subject3209 Farmacologíaen_US
dc.subject320708 Hematologíaen_US
dc.subject.otherAsciminiben_US
dc.subject.otherTyrosine Kinase Inhibitors (Tkis)en_US
dc.subject.otherCytopeniaen_US
dc.subject.otherSubtherapeutic Dosingen_US
dc.titleMolecular response with asciminib 20 mg QD in a patient intolerant to multiple TKIsen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1007/s00277-025-06339-5en_US
dc.identifier.scopus105002164409-
dc.identifier.isi001461146000001-
dc.contributor.orcid0000-0001-6955-2290-
dc.contributor.orcidNO DATA-
dc.contributor.orcid0000-0002-0293-5614-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcid0000-0001-5465-3355-
dc.contributor.orcidNO DATA-
dc.contributor.orcid0009-0006-9649-4050-
dc.contributor.orcid0000-0002-4796-1445-
dc.contributor.orcid0000-0002-4862-4088-
dc.contributor.orcid0000-0002-2070-3227-
dc.contributor.orcid0000-0003-0505-5126-
dc.contributor.authorscopusid8940351300-
dc.contributor.authorscopusid57902847700-
dc.contributor.authorscopusid58658262000-
dc.contributor.authorscopusid59728064800-
dc.contributor.authorscopusid55482691500-
dc.contributor.authorscopusid59727686200-
dc.contributor.authorscopusid55912748500-
dc.contributor.authorscopusid57550315700-
dc.contributor.authorscopusid57902217400-
dc.contributor.authorscopusid7005775092-
dc.contributor.authorscopusid12759635600-
dc.contributor.authorscopusid58355791500-
dc.contributor.authorscopusid57216532422-
dc.contributor.authorscopusid6602513846-
dc.identifier.eissn1432-0584-
dc.description.lastpage3009en_US
dc.description.firstpage3007en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid616098-
dc.contributor.daisngid19596908-
dc.contributor.daisngid19473036-
dc.contributor.daisngid72969968-
dc.contributor.daisngid49909292-
dc.contributor.daisngid6543176-
dc.contributor.daisngid13756377-
dc.contributor.daisngid26054558-
dc.contributor.daisngid73031682-
dc.contributor.daisngid13569576-
dc.contributor.daisngid2469898-
dc.contributor.daisngid54706386-
dc.contributor.daisngid13982043-
dc.contributor.daisngid2469900-
dc.description.numberofpages3en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Stuckey, R-
dc.contributor.wosstandardWOS:Bullón, LN-
dc.contributor.wosstandardWOS:Borrego, AB-
dc.contributor.wosstandardWOS:Ballester, VV-
dc.contributor.wosstandardWOS:Rodríguez-Medina, C-
dc.contributor.wosstandardWOS:Curbelo, AM-
dc.contributor.wosstandardWOS:Pinedo, LG-
dc.contributor.wosstandardWOS:Ochando, MT-
dc.contributor.wosstandardWOS:Vaz, AV-
dc.contributor.wosstandardWOS:Perera, MD-
dc.contributor.wosstandardWOS:Bilbao-Sieyro, C-
dc.contributor.wosstandardWOS:Rodríguez, JFL-
dc.contributor.wosstandardWOS:Segura-Díaz, A-
dc.contributor.wosstandardWOS:Gómez-Casares, MT-
dc.date.coverdateAbril 2025en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr0,912
dc.description.jcr3,0
dc.description.sjrqQ1
dc.description.jcrqQ2
dc.description.scieSCIE
dc.description.miaricds11,0
item.fulltextCon texto completo-
item.grantfulltextopen-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-4796-1445-
crisitem.author.orcid0000-0003-0505-5126-
crisitem.author.fullNameBilbao Sieyro, Cristina-
crisitem.author.fullNameLópez Rodríguez, Juan Francisco-
crisitem.author.fullNameSegura Díaz, Adrian-
crisitem.author.fullNameGómez Casares, María Teresa-
Colección:Artículos
Adobe PDF (611,99 kB)
Vista resumida

Google ScholarTM

Verifica

Altmetric


Comparte



Exporta metadatos



Los elementos en ULPGC accedaCRIS están protegidos por derechos de autor con todos los derechos reservados, a menos que se indique lo contrario.