Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/133324
DC FieldValueLanguage
dc.contributor.authorGroba Marco, Maria Del Valen_US
dc.contributor.authorCabrera Santana, Miriamen_US
dc.contributor.authorGalvan Ruiz, Marioen_US
dc.contributor.authorFernández de Sanmamed, Miguelen_US
dc.contributor.authorRomero Lujan, Jose Luisen_US
dc.contributor.authorGonzález Martin, Jesus Mariaen_US
dc.contributor.authorSantana Ortega, Luis Manuelen_US
dc.contributor.authorVazquez Espinar, Mariaen_US
dc.contributor.authorPortela Torrón, Francisco Antonioen_US
dc.contributor.authorPena Morant, Vicenteen_US
dc.contributor.authorCaballero Dorta, Eduardo Joséen_US
dc.contributor.authorGarcía Quintana, Antonioen_US
dc.date.accessioned2024-10-01T11:34:43Z-
dc.date.available2024-10-01T11:34:43Z-
dc.date.issued2024en_US
dc.identifier.issn2077-0383en_US
dc.identifier.otherWoS-
dc.identifier.urihttp://hdl.handle.net/10553/133324-
dc.description.abstractBackground: Cardiac donation after circulatory death (DCD) is an emerging paradigm in organ transplantation. However, this technique is recent and has only been implemented by highly experienced centers. This study compares the characteristics and outcomes of thoraco-abdominal normothermic regional perfusion (TANRP) and static cold-storage DCD and traditional donation after brain death (DBD) cardiac transplants (CT) in a newly stablished transplant program with restricted donor availability. Method: We performed a retrospective, single-center study of all adult patients who underwent a CT between November 2019 and December 2023, with a follow-up conducted until August 2024. Data were retrieved from medical records. A review of the current literature on DCD CT was conducted to provide a broader context for our findings. The primary outcome was survival at 6 months after transplantation. Results: During the study period, 76 adults (median age 56 years [IQR: 50-63 years]) underwent CT, and 12 (16%) were DCD donors. DCD donors had a similar age (46 vs. 47 years, p = 0.727), were mostly male (92%), and one patient had left ventricular dysfunction during the intraoperative DCD process. There were no significant differences in recipients' characteristics. Survival was similar in the DCD group compared to DBD at 6 months (100 vs. 94%) and 12 months post-CT survival (92% vs. 94%), p = 0.82. There was no primary graft dysfunction in the DCD group (9% in DBD, p = 0.581). The median total hospital stay was longer in the DCD group (46 vs. 21 days, p = 0.021). An increase of 150% in transplantation activity due to DCD was estimated. Conclusions: In a new CT program that utilized older donors and included recipients with similar illnesses and comorbidities, comparable outcomes between DCD and DBD hearts were observed. DCD was rapidly incorporated into the transplant activity, demonstrating an expedited learning curve and significantly increasing the availability of donor hearts.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Clinical Medicineen_US
dc.sourceJournal Of Clinical Medicine [ISSN 2077-0383] ,v. 13 (17), (Septiembre 2024)en_US
dc.subject320501 Cardiologíaen_US
dc.subject321307 Cirugía del corazónen_US
dc.subject321314 Cirugía de los trasplantesen_US
dc.subject.otherPerfusionen_US
dc.subject.otherDonationen_US
dc.subject.otherCardiac Transplanten_US
dc.subject.otherCardiac Surgeryen_US
dc.subject.otherHeart Failureen_US
dc.subject.otherDonation After Circulatory Deathen_US
dc.subject.otherDonation After Brain Deathen_US
dc.subject.otherIn Situ Perfusionen_US
dc.subject.otherEx Situ Perfusionen_US
dc.subject.otherThoraco-Abdominal Normothermic Regional Perfusionen_US
dc.subject.otherDonor Poolen_US
dc.titleExpanding Horizons in Cardiac Transplant: Efficacy and Outcomes of Circulatory and Brain Death Donor Hearts in a Newly Implemented Cardiac Transplant Program with Limited Donor Accessibility and a Literature Reviewen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/jcm13174972en_US
dc.identifier.isi001311046000001-
dc.identifier.eissn2077-0383-
dc.identifier.issue17-
dc.relation.volume13en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.contributor.daisngid59737260-
dc.contributor.daisngid46450851-
dc.contributor.daisngid27338678-
dc.contributor.daisngid7243471-
dc.contributor.daisngid59823707-
dc.contributor.daisngid11577897-
dc.contributor.daisngid44922534-
dc.contributor.daisngid62828914-
dc.contributor.daisngid30245045-
dc.contributor.daisngid62879449-
dc.contributor.daisngid46443244-
dc.contributor.daisngid46318534-
dc.description.numberofpages14en_US
dc.utils.revisionen_US
dc.contributor.wosstandardWOS:Marco, MDG-
dc.contributor.wosstandardWOS:Santana, MC-
dc.contributor.wosstandardWOS:Ruiz, MG-
dc.contributor.wosstandardWOS:de Sanmamed, MF-
dc.contributor.wosstandardWOS:Lujan, JLR-
dc.contributor.wosstandardWOS:Martin, JMG-
dc.contributor.wosstandardWOS:Ortega, LS-
dc.contributor.wosstandardWOS:Espinar, MV-
dc.contributor.wosstandardWOS:Torron, FP-
dc.contributor.wosstandardWOS:Morant, VP-
dc.contributor.wosstandardWOS:Dorta, EJC-
dc.contributor.wosstandardWOS:Quintana, AG-
dc.date.coverdateSeptiembre 2024en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr0,882
dc.description.jcr3,9
dc.description.sjrqQ1
dc.description.jcrqQ2
dc.description.scieSCIE
dc.description.miaricds10,5
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.fullNameGroba Marco, Maria Del Val-
crisitem.author.fullNameSantana Ortega, Luis Manuel-
crisitem.author.fullNamePortela Torrón, Francisco Antonio-
crisitem.author.fullNameCaballero Dorta, Eduardo José-
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