Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/133324
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Groba Marco, Maria Del Val | en_US |
dc.contributor.author | Cabrera Santana, Miriam | en_US |
dc.contributor.author | Galvan Ruiz, Mario | en_US |
dc.contributor.author | Fernández de Sanmamed, Miguel | en_US |
dc.contributor.author | Romero Lujan, Jose Luis | en_US |
dc.contributor.author | González Martin, Jesus Maria | en_US |
dc.contributor.author | Santana Ortega, Luis Manuel | en_US |
dc.contributor.author | Vazquez Espinar, Maria | en_US |
dc.contributor.author | Portela Torrón, Francisco Antonio | en_US |
dc.contributor.author | Pena Morant, Vicente | en_US |
dc.contributor.author | Caballero Dorta, Eduardo José | en_US |
dc.contributor.author | García Quintana, Antonio | en_US |
dc.date.accessioned | 2024-10-01T11:34:43Z | - |
dc.date.available | 2024-10-01T11:34:43Z | - |
dc.date.issued | 2024 | en_US |
dc.identifier.issn | 2077-0383 | en_US |
dc.identifier.other | WoS | - |
dc.identifier.uri | http://hdl.handle.net/10553/133324 | - |
dc.description.abstract | Background: Cardiac donation after circulatory death (DCD) is an emerging paradigm in organ transplantation. However, this technique is recent and has only been implemented by highly experienced centers. This study compares the characteristics and outcomes of thoraco-abdominal normothermic regional perfusion (TANRP) and static cold-storage DCD and traditional donation after brain death (DBD) cardiac transplants (CT) in a newly stablished transplant program with restricted donor availability. Method: We performed a retrospective, single-center study of all adult patients who underwent a CT between November 2019 and December 2023, with a follow-up conducted until August 2024. Data were retrieved from medical records. A review of the current literature on DCD CT was conducted to provide a broader context for our findings. The primary outcome was survival at 6 months after transplantation. Results: During the study period, 76 adults (median age 56 years [IQR: 50-63 years]) underwent CT, and 12 (16%) were DCD donors. DCD donors had a similar age (46 vs. 47 years, p = 0.727), were mostly male (92%), and one patient had left ventricular dysfunction during the intraoperative DCD process. There were no significant differences in recipients' characteristics. Survival was similar in the DCD group compared to DBD at 6 months (100 vs. 94%) and 12 months post-CT survival (92% vs. 94%), p = 0.82. There was no primary graft dysfunction in the DCD group (9% in DBD, p = 0.581). The median total hospital stay was longer in the DCD group (46 vs. 21 days, p = 0.021). An increase of 150% in transplantation activity due to DCD was estimated. Conclusions: In a new CT program that utilized older donors and included recipients with similar illnesses and comorbidities, comparable outcomes between DCD and DBD hearts were observed. DCD was rapidly incorporated into the transplant activity, demonstrating an expedited learning curve and significantly increasing the availability of donor hearts. | en_US |
dc.language | eng | en_US |
dc.relation.ispartof | Journal of Clinical Medicine | en_US |
dc.source | Journal Of Clinical Medicine [ISSN 2077-0383] ,v. 13 (17), (Septiembre 2024) | en_US |
dc.subject | 320501 Cardiología | en_US |
dc.subject | 321307 Cirugía del corazón | en_US |
dc.subject | 321314 Cirugía de los trasplantes | en_US |
dc.subject.other | Perfusion | en_US |
dc.subject.other | Donation | en_US |
dc.subject.other | Cardiac Transplant | en_US |
dc.subject.other | Cardiac Surgery | en_US |
dc.subject.other | Heart Failure | en_US |
dc.subject.other | Donation After Circulatory Death | en_US |
dc.subject.other | Donation After Brain Death | en_US |
dc.subject.other | In Situ Perfusion | en_US |
dc.subject.other | Ex Situ Perfusion | en_US |
dc.subject.other | Thoraco-Abdominal Normothermic Regional Perfusion | en_US |
dc.subject.other | Donor Pool | en_US |
dc.title | Expanding Horizons in Cardiac Transplant: Efficacy and Outcomes of Circulatory and Brain Death Donor Hearts in a Newly Implemented Cardiac Transplant Program with Limited Donor Accessibility and a Literature Review | en_US |
dc.type | info:eu-repo/semantics/Article | en_US |
dc.type | Article | en_US |
dc.identifier.doi | 10.3390/jcm13174972 | en_US |
dc.identifier.isi | 001311046000001 | - |
dc.identifier.eissn | 2077-0383 | - |
dc.identifier.issue | 17 | - |
dc.relation.volume | 13 | en_US |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Artículo | en_US |
dc.contributor.daisngid | 59737260 | - |
dc.contributor.daisngid | 46450851 | - |
dc.contributor.daisngid | 27338678 | - |
dc.contributor.daisngid | 7243471 | - |
dc.contributor.daisngid | 59823707 | - |
dc.contributor.daisngid | 11577897 | - |
dc.contributor.daisngid | 44922534 | - |
dc.contributor.daisngid | 62828914 | - |
dc.contributor.daisngid | 30245045 | - |
dc.contributor.daisngid | 62879449 | - |
dc.contributor.daisngid | 46443244 | - |
dc.contributor.daisngid | 46318534 | - |
dc.description.numberofpages | 14 | en_US |
dc.utils.revision | Sí | en_US |
dc.contributor.wosstandard | WOS:Marco, MDG | - |
dc.contributor.wosstandard | WOS:Santana, MC | - |
dc.contributor.wosstandard | WOS:Ruiz, MG | - |
dc.contributor.wosstandard | WOS:de Sanmamed, MF | - |
dc.contributor.wosstandard | WOS:Lujan, JLR | - |
dc.contributor.wosstandard | WOS:Martin, JMG | - |
dc.contributor.wosstandard | WOS:Ortega, LS | - |
dc.contributor.wosstandard | WOS:Espinar, MV | - |
dc.contributor.wosstandard | WOS:Torron, FP | - |
dc.contributor.wosstandard | WOS:Morant, VP | - |
dc.contributor.wosstandard | WOS:Dorta, EJC | - |
dc.contributor.wosstandard | WOS:Quintana, AG | - |
dc.date.coverdate | Septiembre 2024 | en_US |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-MED | en_US |
dc.description.sjr | 0,882 | |
dc.description.jcr | 3,9 | |
dc.description.sjrq | Q1 | |
dc.description.jcrq | Q2 | |
dc.description.scie | SCIE | |
dc.description.miaricds | 10,5 | |
item.fulltext | Sin texto completo | - |
item.grantfulltext | none | - |
crisitem.author.dept | Departamento de Ciencias Médicas y Quirúrgicas | - |
crisitem.author.dept | Departamento de Ciencias Médicas y Quirúrgicas | - |
crisitem.author.fullName | Groba Marco, Maria Del Val | - |
crisitem.author.fullName | Santana Ortega, Luis Manuel | - |
crisitem.author.fullName | Portela Torrón, Francisco Antonio | - |
crisitem.author.fullName | Caballero Dorta, Eduardo José | - |
Appears in Collections: | Artículos |
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