Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/130588
DC FieldValueLanguage
dc.contributor.authorDíaz-Cambronero, Óscaren_US
dc.contributor.authorMazzinari, Guidoen_US
dc.contributor.authorErrando, Carlos L.en_US
dc.contributor.authorGarutti, Ignacioen_US
dc.contributor.authorGurumeta, Alfredo A.en_US
dc.contributor.authorSerrano, Ana B.en_US
dc.contributor.authorEsteve, Neusen_US
dc.contributor.authorMontañes, Maria V.en_US
dc.contributor.authorNeto, Ary S.en_US
dc.contributor.authorHollmann, Markus W.en_US
dc.contributor.authorSchultz, Marcus J.en_US
dc.contributor.authorArgente Navarro, Maria P.en_US
dc.contributor.authorPérez, María del Pino Herediaen_US
dc.contributor.authorNúñez, Victoria Carvajalen_US
dc.contributor.authorLinero, Inmaculada Benítezen_US
dc.contributor.authorAparicio, María del Pilar Garcíaen_US
dc.contributor.authorMiguel González de la Mata, Alba Maríaen_US
dc.contributor.authorMarín, Alejandro Martínezen_US
dc.contributor.authorMora Fernández, Luis Carlosen_US
dc.contributor.authorRobles, Ana Ferreren_US
dc.contributor.authorGonzález, David Fabiánen_US
dc.contributor.authorGil, Marta Mariscalen_US
dc.contributor.authorRomero, Germán Gómezen_US
dc.contributor.authorMontero, Begoña Ayasen_US
dc.contributor.authorAlberola Estellés, María Joséen_US
dc.contributor.authorJaén, Salomé Matosesen_US
dc.contributor.authorOrtolá, Carlos Ferrandoen_US
dc.contributor.authorVargas, Esther Romeroen_US
dc.contributor.authorJaramago, Julia Martínen_US
dc.contributor.authorMataix, Javier Barrioen_US
dc.contributor.authorGonzalez, Estefanía Martínezen_US
dc.contributor.authorSanus, Alma Casasempereen_US
dc.contributor.authorFas Vicent, María Joséen_US
dc.contributor.authorOrtega Saavedra, Juanen_US
dc.contributor.authorPallardó López, María Angelesen_US
dc.contributor.authorChornet, María Rossellóen_US
dc.contributor.authorHernández, Alicia Sánchezen_US
dc.contributor.authorGarcía Belmonte, José Pedroen_US
dc.contributor.authorMarcelino Martín, Miguel Ángelen_US
dc.contributor.authorRodríguez Domínguez, Montserrat Noeliaen_US
dc.contributor.authorBecerra Bolaños, Ángelen_US
dc.contributor.authorTrujillo-Morales, Héctoren_US
dc.contributor.authorPalacín, Rebeca Pascualen_US
dc.contributor.authorBartolomé Pacheco, María Joséen_US
dc.contributor.authorPérez, Osvaldoen_US
dc.contributor.authorRabago, José Luisen_US
dc.contributor.authorCaral, Pere Vilaen_US
dc.contributor.authorFernández Cortes, Ana Isabelen_US
dc.contributor.authorMilán, Marta Caballeroen_US
dc.contributor.authorGarcía, Lourdes Pérezen_US
dc.contributor.authorAlsina, Carme Subiràen_US
dc.contributor.authorGrauwinkel, Cassandra Gimenoen_US
dc.contributor.authorLópez González, José Manuelen_US
dc.contributor.authorJiménez Gómez, Bárbara Maríaen_US
dc.contributor.authorGasalla Cadórniga, Alvaro Manuelen_US
dc.contributor.authorGonzález, Iván Areánen_US
dc.contributor.authorGil Campelo, María Ángelesen_US
dc.contributor.authorSolores, Felix Lobatoen_US
dc.contributor.authorSantiago, Ana Crespoen_US
dc.contributor.authorOrtíz, Alvaro Eliceguien_US
dc.contributor.authorGarcía, Isabel Gómezen_US
dc.contributor.authorPerote, Lara Castellanosen_US
dc.contributor.authorMurillo, Miguel Miróen_US
dc.contributor.authorRueda, Fernando Ramascoen_US
dc.contributor.authorRoca, Antonio Planasen_US
dc.contributor.authorIrujo, Javier Ariñoen_US
dc.contributor.authorElguezábal, Pedro de la Calleen_US
dc.contributor.authorPalacios, Raúl Villalbaen_US
dc.contributor.authorSaavedra, Bárbaraen_US
dc.contributor.authorLearte, Mar Establésen_US
dc.contributor.authorLópez, Sandra Gadínen_US
dc.contributor.authorGonzález, Rosa Sanzen_US
dc.contributor.authorMelchor, Javier Ripollésen_US
dc.contributor.authorHurtado, Eugenio Martínezen_US
dc.contributor.authorAbad-Motos, Aneen_US
dc.contributor.authorLópez, María Uribarrien_US
dc.contributor.authorMartínez, Cristina Miguelen_US
dc.date.accessioned2024-05-20T18:27:24Z-
dc.date.available2024-05-20T18:27:24Z-
dc.date.issued2023en_US
dc.identifier.issn0007-0912en_US
dc.identifier.urihttp://hdl.handle.net/10553/130588-
dc.description.abstractBackground: The incidence of postoperative residual curarisation remains unacceptably high. We assessed whether an educational intervention on perioperative neuromuscular block management can reduce it. Methods: In this multicentre, cluster randomised crossover trial, centres were allocated to receive an educational intervention either in a first or a second period. The educational intervention consisted of a lecture about neuromuscular management key points, including quantitative neuromuscular monitoring and use of reversal agents. The lecture was streamed to allow repetition. Additionally, memory cards were distributed in each operating theatre. The primary outcome was postoperative residual curarisation in the PACU. Secondary outcomes were frequency of quantitative neuromuscular monitoring, use of reversal agents, and incidence of postoperative pulmonary complications during hospital stay. Measurements were performed before randomisation and after the first and the second period. The effect of the educational intervention was estimated using multivariable mixed effects logistic regression models. Results: We included 2314 subjects in 34 Spanish centres. Postoperative residual curarisation incidence was not affected by the educational intervention (odds ratio [OR] 0.90 [95% confidence interval {CI}: 0.51–1.58]; P=0.717 and 1.30 [0.73–2.30]; P=0.371] for first and second time-period interaction). The educational intervention increased the quantitative neuromuscular monitor usage (OR 2.04 [95% CI: 1.31–3.19]; P=0.002), the use of reversal agents was unchanged (OR 0.79 [95% CI: 0.50–1.26]; P=0.322), and the incidence of postoperative pulmonary complications decreased (OR 0.19 [95% CI: 0.10–0.35]; P<0.001). Conclusions: An educational intervention on perioperative neuromuscular block management did not reduce the incidence of postoperative residual curarisation nor increase reversal, despite increased quantitative neuromuscular monitoring. Sugammadex reversal was associated with reduced postoperative residual curarisation. The educational intervention was associated with a decrease in postoperative pulmonary complications. Clinical trial registration: NCT03128151.en_US
dc.languageengen_US
dc.relation.ispartofBritish journal of anaesthesiaen_US
dc.sourceBritish journal of anaesthesia [ISSN 0007-0912], v. 131(3), p. 482-490 (Septiembre 2023)en_US
dc.subject32 Ciencias médicasen_US
dc.subject3201 Ciencias clínicasen_US
dc.subject321303 Anestesiologíaen_US
dc.subject.otherAcetylcholinesterase inhibitoren_US
dc.subject.otherNeuromuscular blocken_US
dc.subject.otherNeuromuscular monitoringen_US
dc.subject.otherPostoperative residual curarisationen_US
dc.subject.otherSugammadexen_US
dc.titleAn educational intervention to reduce the incidence of postoperative residual curarisation: a cluster randomised crossover trial in patients undergoing general anaesthesiaen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.bja.2023.02.031en_US
dc.identifier.pmid37087332-
dc.identifier.scopus2-s2.0-85153096406-
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dc.description.lastpage490en_US
dc.identifier.issue3-
dc.description.firstpage482en_US
dc.relation.volume131en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.numberofpages9en_US
dc.utils.revisionen_US
dc.date.coverdateSeptiembre 2023en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr2,397
dc.description.jcr9,8
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
dc.description.miaricds11,0
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-2817-3144-
crisitem.author.fullNameBecerra Bolaños, Ángel-
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