1. accedaCRIS
  2. Publicaciones
  3. Artículos
Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/120637
Campo DC Valoridioma
dc.contributor.authorGutierrez, Alejandro H.en_US
dc.contributor.authorMazariegos, Marina S.en_US
dc.contributor.authorAlemany, Susanaen_US
dc.contributor.authorNevzorova, Yulia A.en_US
dc.contributor.authorCubero, Francisco Javieren_US
dc.contributor.authorSanz-García, Carlosen_US
dc.date.accessioned2023-02-22T14:44:34Z-
dc.date.available2023-02-22T14:44:34Z-
dc.date.issued2023en_US
dc.identifier.issn0925-4439en_US
dc.identifier.otherScopus-
dc.identifier.urihttp://hdl.handle.net/10553/120637-
dc.description.abstractThe cytoplasmic protein tumor progression locus 2 (TPL2), also known as cancer Osaka thyroid (Cot), or MAP3K8, is thought to have a significant role in a variety of cancers and illnesses and it is a key component in the activation pathway for the expression of inflammatory mediators. Despite the tight connection between inflammation and TPL2, its function has not been extensively studied in chronic liver disease (CLD), a major cause of morbidity and mortality worldwide. Here, we analyze more in detail the significance of TPL2 in CLD to shed light on the pathological and molecular transduction pattern of TPL2 during the progression of CLD. This might result in important advancements and enable progress in the diagnosis and treatment of CLD.en_US
dc.languageengen_US
dc.relation.ispartofBiochimica et Biophysica Acta - Molecular Basis of Diseaseen_US
dc.sourceBiochimica et Biophysica Acta - Molecular Basis of Disease [ISSN 0925-4439], v. 1869 (4): 166660, (Abril 2023)en_US
dc.subject32 Ciencias médicasen_US
dc.subject320713 Oncologíaen_US
dc.subject2302 Bioquímicaen_US
dc.subject.otherCanceren_US
dc.subject.otherCancer Osaka Thyroiden_US
dc.subject.otherChronic Liver Diseaseen_US
dc.subject.otherInflammationen_US
dc.subject.otherMapken_US
dc.subject.otherTumor Progression Locus 2en_US
dc.titleTumor progression locus 2 (TPL2): A Cot-plicated progression from inflammation to chronic liver diseaseen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.1016/j.bbadis.2023.166660en_US
dc.identifier.scopus85147690921-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.authorscopusid58096257900-
dc.contributor.authorscopusid55557951900-
dc.contributor.authorscopusid7003796446-
dc.contributor.authorscopusid14037630400-
dc.contributor.authorscopusid8517959700-
dc.contributor.authorscopusid55748804500-
dc.identifier.eissn1879-260X-
dc.identifier.issue4-
dc.relation.volume1869en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.numberofpages9en_US
dc.utils.revisionSíen_US
dc.date.coverdateAbril 2023en_US
dc.identifier.ulpgcSíen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr1,58
dc.description.jcr4,2
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
dc.description.miaricds11,0
item.grantfulltextopen-
item.fulltextCon texto completo-
Colección:Artículos
Adobe PDF (2,66 MB)
Vista resumida

Citas SCOPUSTM   

1
actualizado el 30-mar-2025

Visitas

54
actualizado el 01-nov-2024

Descargas

32
actualizado el 01-nov-2024

Google ScholarTM

Verifica

Altmetric


Comparte


Exporta metadatos


Los elementos en ULPGC accedaCRIS están protegidos por derechos de autor con todos los derechos reservados, a menos que se indique lo contrario.