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Title: Evaluation of Pulmonary Hypertension in Dogs with Heartworm Disease Using the Computed Tomographic Pulmonary Trunk to Aorta Diameter Ratio
Authors: Matos Rivero, Jorge Isidoro 
Falcón Cordón, Yaiza 
García Rodríguez, Sara Nieves 
Costa Rodríguez, Noelia 
Montoya Alonso, José Alberto 
Carretón Gómez, Elena 
UNESCO Clasification: 310904 Medicina interna
Keywords: Animal Diseases
Computed Tomography
Dirofilaria Immitis
Heartworm Disease, et al
Issue Date: 2022
Journal: Animals 
Abstract: Dirofilaria immitis causes proliferative pulmonary endoarteritis that leads to the appearance of chronic precapillary pulmonary hypertension (PH) in dogs. Pulmonary trunk to aorta ratio (PT:Ao ratio) obtained by computed tomography (CT) was studied and the quantitative measure of the diameters of the pulmonary trunk (PT), the descending thoracic aorta (DAo) and ascending thoracic aorta (AAo) were evaluated for the determination of the presence of moderate to severe PH in 59 dogs. The diagnosis of PH was echocardiographically determined, based on the determination of the right pulmonary artery distensibility (RPAD) index (<29.5%), and compared with other parameters for estimating PH. The results showed a very high concordance: 0.976 (p-value 0.000) between the two CT methods (PT:DAo and PT:AAo) with an excellent intraclass correlation coefficient > 0.95. Moreover, cut-off values of ≥1.111 for PT:DAo, and ≥1.057 for PT:AAo were determined for dogs with an RPAD index < 29.5%, which suggests a cut-off value between healthy dogs and the presence of PH. As has been previously published, The PT:Ao ratios did not determine the presence of mild PH, so the measurements cannot be considered useful for the early diagnosis of PH in dogs with heartworm
ISSN: 2076-2615
DOI: 10.3390/ani12182441
Source: Animals[EISSN 2076-2615],v. 12 (18), (Septiembre 2022)
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