Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/114140
DC FieldValueLanguage
dc.contributor.authorNavarro Santana, Beatriz Fátimaen_US
dc.contributor.authorGarcía Torralba, Esmeraldaen_US
dc.contributor.authorVerdu Soriano, Joseen_US
dc.contributor.authorLaseca, Mariaen_US
dc.contributor.authorMartín Martínez, Aliciaen_US
dc.date.accessioned2022-03-21T15:08:19Z-
dc.date.available2022-03-21T15:08:19Z-
dc.date.issued2022en_US
dc.identifier.issn2005-0380en_US
dc.identifier.otherScopus-
dc.identifier.urihttp://hdl.handle.net/10553/114140-
dc.description.abstractObjective: To assess the benefit of protective ostomies on anastomotic leak rate, urgent reoperations, and mortality due to anastomotic leak complications in ovarian cancer surgery. Methods: A systematic literature search was performed in MEDLINE, Web of Science, ClinicalTrials.gov, and the Cochrane Central Register of Controlled Trials for all studies on anastomotic leak and ostomy formation related to ovarian cancer surgery. Non-controlled studies, case series, abstracts, case reports, study protocols, and letters to the editor were excluded. Meta-analysis was performed on the primary endpoint of anastomotic leak rate. Subgroup analysis was carried out based on type of bowel resection and bevacizumab use. Secondary endpoints were urgent re-operations and mortality associated with anastomotic leak, length of hospital stay, postoperative complications, 30-day readmission rate, adjuvant chemotherapy, survival, and reversal surgery in ostomy and non-ostomy patients. Results: A total of 17 studies (2,719 patients) were included: 16 retrospective cohort studies, and 1 case-control study. Meta-analysis of 17 studies did not show a decrease in anastomotic leak rate in ostomy patients (odds ratio [OR]=1.01; 95% confidence interval [CI]=0.60–1.70; p=0.980). Meta-analysis of ten studies (1,452 women) did not find a decrease in urgent reoperations in the ostomy group (OR=0.72; 95% CI=0.35–1.46; p=0.360). Other outcomes were not considered for meta-analysis due to the lack of data in included studies. Conclusion: Protective ostomies did not decrease anastomotic leak rates, and urgent re-operations in ovarian cancer surgery. This evidence supports the use of ostomies in very select cases.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Gynecologic Oncologyen_US
dc.sourceJournal of Gynecologic Oncology[ISSN 2005-0380],v. 33 (2), (Marzo 2022)en_US
dc.subject32 Ciencias médicasen_US
dc.subject320108 Ginecologíaen_US
dc.subject320101 Oncologíaen_US
dc.subject.otherAnastomotic Leaken_US
dc.subject.otherOstomyen_US
dc.subject.otherOvarian Neoplasmsen_US
dc.titleProtective ostomies in ovarian cancer surgery: a systematic review and meta-analysisen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3802/jgo.2022.33.e21en_US
dc.identifier.scopus85125882086-
dc.contributor.orcid0000-0002-5572-7843-
dc.contributor.orcid0000-0002-3744-2182-
dc.contributor.orcid0000-0002-8307-7323-
dc.contributor.orcid0000-0002-0777-3124-
dc.contributor.orcid0000-0002-4237-6378-
dc.contributor.authorscopusid57487788000-
dc.contributor.authorscopusid57486971300-
dc.contributor.authorscopusid57487788100-
dc.contributor.authorscopusid57461286900-
dc.contributor.authorscopusid57487625800-
dc.identifier.eissn2005-0399-
dc.identifier.issue2-
dc.relation.volume33en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.numberofpages16en_US
dc.utils.revisionen_US
dc.date.coverdateMarzo 2022en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr1,358
dc.description.jcr4,401
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
dc.description.miaricds10,6
item.grantfulltextopen-
item.fulltextCon texto completo-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0002-4237-6378-
crisitem.author.fullNameNavarro Santana, Beatriz Fátima-
crisitem.author.fullNameMartín Martínez, Alicia-
Appears in Collections:Artículos
Thumbnail
Adobe PDF (1,03 MB)
Show simple item record

Page view(s)

21
checked on Jun 12, 2022

Download(s)

9
checked on Jun 12, 2022

Google ScholarTM

Check

Altmetric


Share



Export metadata



Items in accedaCRIS are protected by copyright, with all rights reserved, unless otherwise indicated.