Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/113997
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dc.contributor.authorMayneris-Perxachs, Jen_US
dc.contributor.authorSala-Vila, Aen_US
dc.contributor.authorChisaguano, Men_US
dc.contributor.authorCastellote, AIen_US
dc.contributor.authorEstruch, Ren_US
dc.contributor.authorCovas, MIen_US
dc.contributor.authorFito, Men_US
dc.contributor.authorSalas Salvado, Jen_US
dc.contributor.authorMartinez-Gonzalez, MAen_US
dc.contributor.authorLamuela-Raventos, Ren_US
dc.contributor.authorRos, Een_US
dc.contributor.authorLopez-Sabater, MCen_US
dc.contributor.editorAtkin, Stephen L.-
dc.date.accessioned2022-03-10T15:19:21Z-
dc.date.available2022-03-10T15:19:21Z-
dc.date.issued2014en_US
dc.identifier.issn1932-6203en_US
dc.identifier.urihttp://hdl.handle.net/10553/113997-
dc.description.abstractBackground & Aims: Metabolic syndrome (MetS) has become an important public concern due to its increasing prevalence. An altered fatty acid composition has been associated with MetS, but the Mediterranean diet has been shown to have a protective effect. The aim of the present study was to analyze the influence of a Mediterranean dietary pattern, as assessed by the biomarkers of food supplied, on the plasma fatty acid composition and its relation with MetS after 1 year of intervention. Methods: A total of 424 subjects were randomly selected from the PREDIMED randomized dietary trial after completing a 1-year intervention program. Participants aged 55 to 80 years and at high risk of cardiovascular disease were randomly assigned to three dietary interventions: Mediterranean diet supplemented with virgin olive oil or nuts, or a low-fat diet. Results: After 1 year of intervention participants in the virgin olive oil group showed significantly increased plasma concentrations of palmitic and oleic acids, but reduced proportions of margaric, stearic, and linoleic acids. In turn, subjects in the nut group showed significantly increased levels of palmitic, linoleic, and α-linolenic acids, but reduced proportions of myristic, margaric, palmitoleic, and dihommo-γ-linoleic acids. Increases in the biomarkers of foods supplied to the Mediterranean diet groups, i.e., oleic and α-linolenic acids, were beneficially associated with the incidence, reversion and prevalence of MetS. No weight changes were observed among participants. Conclusions: The nut and olive oil diets induced a fatty acid composition that has been shown to be beneficial in the face of MetS. Therefore, a Mediterranean diet rich in fats of vegetable origin may be a useful tool for the management of MetS without the need for concerns over weight gain due to its high fat content.en_US
dc.languageengen_US
dc.relation.ispartofPLoS ONEen_US
dc.sourcePLoS ONE [ISSN 1932-6203], v. 9 (3) e85202 (Marzo 2014)en_US
dc.subject32 Ciencias médicasen_US
dc.subject3206 Ciencias de la nutriciónen_US
dc.subject320502 Endocrinologíaen_US
dc.subject320704 Patología cardiovascularen_US
dc.subject.otherDieten_US
dc.subject.otherType 2 diabetesen_US
dc.subject.otherFatsen_US
dc.subject.otherBlood plasmaen_US
dc.subject.otherFatty acidsen_US
dc.subject.otherVegetable oilsen_US
dc.subject.otherFooden_US
dc.subject.otherBiomarkersen_US
dc.subject.otherPREDIMEDen_US
dc.titleEffects of 1-Year Intervention with a Mediterranean Diet on Plasma Fatty Acid Composition and Metabolic Syndrome in a Population at High Cardiovascular Risken_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typearticleen_US
dc.identifier.doi10.1371/journal.pone.0085202en_US
dc.identifier.pmid24651160-
dc.identifier.scopus2-s2.0-84922252838-
dc.identifier.isiWOS:000333352800002-
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dc.identifier.issue3-
dc.relation.volume9en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.notasThe authors thank the participants for their enthusiastic collaboration, the PREDIMED personnel for excellent assistance and the personnel of all affiliated primary care centres. The PREDIMED Study Investigators are: Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, Barcelona, Spain: C. Viñas, R. Casas, J.M. Baena, M. Oller, J. Amat, I. Duaso, Y. García, C. Iglesias, and J. Benavent. University of Navarra, Primary Care Division Centres, Pamplona, Spain: A. Sánchez-Tainta, E. Toledo, P. Buil-Cosiales, M. Serrano-Martínez, J. Díez-Espino, A. García-Arellano, I. Zazpe, J. Basterra-Gortari, University Rovira i Virgili, Reus, Spain: R. González, C. Molina, M. Guasch-Ferré, A. Díaz-López, M. Sorli, J. García-Roselló, J. Basora, J. Fernández-Ballart. Institute de Recerca Hospital del Mar, Barcelona, Spain: S. Tello, J. Vila, M. Fitó, H. Schröder, R. University Hospital of Alava,Vitoria, Spain: F. Aros. del Hierro, J.Algorta. University of Málaga, Málaga, Spain: R. Benítez Pont, M. Bianchi Alba, J.Fernández-Crehuet Navajas, E. Gómez-Gracia. Department of Family Medicine, Primary Care Division of Sevilla, Sevilla, Spain: F.J. García, P. Roman, J.M. Santos, J. Lapetra. University of Las Palmas de Gran Canaria, Las Palmas, Spain: J. Álvarez-Pérez, E. Díez Benítez, I. Bautista Castaño, A. Sánchez-Villegas.en_US
dc.description.numberofpages11en_US
dc.utils.revisionen_US
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.contributor.wosstandardAtkin, Stephen L.-
dc.date.coverdateMarzo 2014en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr1,545
dc.description.jcr3,234
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
dc.description.erihplusERIH PLUS
item.grantfulltextopen-
item.fulltextCon texto completo-
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