Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/113672
Campo DC Valoridioma
dc.contributor.authorSacchini, Simonaen_US
dc.contributor.authorHerráez Thomas, Pedro Manuelen_US
dc.contributor.authorArbelo Hernández, Manuel Antonioen_US
dc.contributor.authorEspinosa De Los Monteros Y Zayas, Antonioen_US
dc.contributor.authorSierra Pulpillo, Eva Maríaen_US
dc.contributor.authorRivero Santana, Miguel Antonioen_US
dc.contributor.authorBombardi, Cristianoen_US
dc.contributor.authorFernández Rodríguez, Antonio Jesúsen_US
dc.date.accessioned2022-02-07T15:49:10Z-
dc.date.available2022-02-07T15:49:10Z-
dc.date.issued2022en_US
dc.identifier.issn2306-7381en_US
dc.identifier.otherScopus-
dc.identifier.urihttp://hdl.handle.net/10553/113672-
dc.description.abstractCetacean brain sampling may be an arduous task due to the difficulty of collecting and histologically preparing such rare and large specimens. Thus, one of the main challenges of working with cetaceans’ brains is to establish a valid methodology for an optimal manipulation and fixation of the brain tissue, which allows the samples to be viable for neuroanatomical and neuropathological studies. With this in view, we validated a methodology in order to preserve the quality of such large brains (neuroanatomy/neuropathology) and at the same time to obtain fresh brain samples for toxicological, virological, and microbiological analysis (neuropathology). A fixation protocol adapted to brains, of equal or even three times the size of human brains, was studied and tested. Finally, we investigated the usefulness of a panel of 20 antibodies (neuromarkers) associated with the normal structure and function of the brain, pathogens, age-related, and/or functional variations. The sampling protocol and some of the 20 neuromarkers have been thought to explore neurodegenerative diseases in these long-lived animals. To conclude, many of the typical measures used to evaluate neuropathological changes do not tell us if meaningful cellular changes have occurred. Having a wide panel of antibodies and histochemical techniques available allows for delving into the specific behavior of the neuronal population of the brain nuclei and to get a “fingerprint” of their real status.en_US
dc.languageengen_US
dc.relation.ispartofVeterinary Sciencesen_US
dc.sourceVeterinary Sciences [EISSN 2306-7381], v. 9 (2), 38, (Febrero 2022)en_US
dc.subject3109 Ciencias veterinariasen_US
dc.subject.otherBeaked Whalesen_US
dc.subject.otherCetaceansen_US
dc.subject.otherDolphinsen_US
dc.subject.otherImmunohistochemistryen_US
dc.subject.otherMethodologyen_US
dc.subject.otherNeuroanatomyen_US
dc.subject.otherNeuromarkersen_US
dc.subject.otherNeuropathologyen_US
dc.titleMethodology and Neuromarkers for Cetaceans’ Brainsen_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3390/vetsci9020038en_US
dc.identifier.scopus85123741178-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.orcidNO DATA-
dc.contributor.authorscopusid55185147800-
dc.contributor.authorscopusid57194503614-
dc.contributor.authorscopusid6603561403-
dc.contributor.authorscopusid36928058400-
dc.contributor.authorscopusid15742962600-
dc.contributor.authorscopusid7006991340-
dc.contributor.authorscopusid6508064114-
dc.contributor.authorscopusid56673009900-
dc.identifier.eissn2306-7381-
dc.identifier.issue2-
dc.relation.volume9en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.utils.revisionen_US
dc.date.coverdateFebrero 2022en_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-VETen_US
dc.description.sjr0,524
dc.description.jcr2,4
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.miaricds10,3
item.fulltextCon texto completo-
item.grantfulltextopen-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.orcid0000-0001-6493-1275-
crisitem.author.orcid0000-0001-9316-2882-
crisitem.author.orcid0000-0002-1623-5010-
crisitem.author.orcid0000-0002-7736-3139-
crisitem.author.orcid0000-0003-3749-8845-
crisitem.author.orcid0000-0003-3766-1569-
crisitem.author.orcid0000-0001-5281-0521-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.fullNameSacchini, Simona-
crisitem.author.fullNameHerráez Thomas, Pedro Manuel-
crisitem.author.fullNameArbelo Hernández, Manuel Antonio-
crisitem.author.fullNameEspinosa De Los Monteros Y Zayas, Antonio-
crisitem.author.fullNameSierra Pulpillo, Eva María-
crisitem.author.fullNameRivero Santana, Miguel Antonio-
crisitem.author.fullNameFernández Rodríguez, Antonio Jesús-
Colección:Artículos
Adobe PDF (12 MB)
Vista resumida

Citas SCOPUSTM   

6
actualizado el 24-mar-2024

Visitas

69
actualizado el 01-jul-2023

Descargas

39
actualizado el 01-jul-2023

Google ScholarTM

Verifica

Altmetric


Comparte



Exporta metadatos



Los elementos en ULPGC accedaCRIS están protegidos por derechos de autor con todos los derechos reservados, a menos que se indique lo contrario.