Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/110918
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dc.contributor.authorHernández Socorro, Carmen Rosaen_US
dc.contributor.authorSaavedra Santana, Pedroen_US
dc.contributor.authorLópez Fernández, Juan Carlosen_US
dc.contributor.authorLübbe-Vazquez, Federicoen_US
dc.contributor.authorRuiz Santana, Sergioen_US
dc.date.accessioned2021-07-20T14:00:12Z-
dc.date.available2021-07-20T14:00:12Z-
dc.date.issued2021en_US
dc.identifier.issn2072-6643en_US
dc.identifier.urihttp://hdl.handle.net/10553/110918-
dc.description.abstractNovel ultrasound (US) methods are required to assess qualitative changes in the quadriceps rectus femoris (QRF) muscle when evaluating mechanically ventilated, long-stay ICU patients with suspected neuromuscular acquired weakness (ICUAW). Our aim was to analyze novel US muscle assessment methods in these patients versus healthy controls by carrying out a prospective observational study. Shear wave elastography (SWE) showed, with a receiver operating characteristic (ROC) curve of 0.972 (95% confidence interval (CI) = 0.916–1.000), that patients increased muscle stiffness associated with muscle fibrosis when diagnosed with ICUAW. We also performed, for the first time, superb microvascular imaging (SMI), which is an innovative US technique designed for imaging microvascularization unseen with color Doppler US, and observed that 53.8% of cases had significantly lower QRF muscle microvascular angiogenic activity than controls (p < 0.001). Finally, we used contrast-enhanced ultrasound (CEUS) to analyze maximum and minimum QRF muscle perfusion and obtained a ROC curve of 0.8, but when used as markers for SMI, their diagnostic capacity increased to 0.988 (CI = 0.965–1) and 0.932 (CI = 0.858–1), respectively. These findings show, for the first time, that these novel sonographic muscle methods should be used for their diagnostic capacity when assessing sarcopenic processes associated with this group of critically ill patients.en_US
dc.languageengen_US
dc.relation.ispartofNutrientsen_US
dc.sourceNutrients [ISSN 2072-6643], v. 13(7), 2224, (Junio 2021)en_US
dc.subject32 Ciencias médicasen_US
dc.subject241110 Fisiología del músculoen_US
dc.subject320111 Radiologíaen_US
dc.subject.otherCritical illnessen_US
dc.subject.otherElastographyen_US
dc.subject.otherMuscle massen_US
dc.subject.otherMuscle weaknessen_US
dc.subject.otherQuadriceps femorisen_US
dc.subject.otherSarcopeniaen_US
dc.subject.otherUltrasounden_US
dc.titleNovel high-quality sonographic methods to diagnose muscle wasting in long-stay critically ill patients: Shear wave elastography, superb microvascular imaging and contrast-enhanced ultrasounden_US
dc.typeinfo:eu-repo/semantics/Articleen_US
dc.identifier.doi10.3390/nu13072224en_US
dc.identifier.scopus2-s2.0-85108779010-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.contributor.orcid#NODATA#-
dc.identifier.issue7-
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.description.numberofpages15en_US
dc.utils.revisionen_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-MEDen_US
dc.description.sjr1,287
dc.description.jcr6,706
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
dc.description.miaricds10,6
item.fulltextCon texto completo-
item.grantfulltextopen-
crisitem.author.deptGIR IUIBS: Grupo de investigaciones infecciosas, nutricionales e inflamatorias en pacientes hospitalarios / Study Group on infectious, nutritional and inflammatory diseases in hospitalized patients-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Clínicas-
crisitem.author.deptGIR Estadística-
crisitem.author.deptDepartamento de Matemáticas-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.deptGIR IUIBS: Grupo de investigaciones infecciosas, nutricionales e inflamatorias en pacientes hospitalarios / Study Group on infectious, nutritional and inflammatory diseases in hospitalized patients-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0003-1681-7165-
crisitem.author.orcid0000-0003-3927-3236-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgDepartamento de Matemáticas-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameHernández Socorro, Carmen Rosa-
crisitem.author.fullNameSaavedra Santana, Pedro-
crisitem.author.fullNameLópez Fernández, Juan Carlos-
crisitem.author.fullNameRuiz Santana, Sergio-
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