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Title: Ultrasound evaluation of adrenal gland size in clinically healthy dogs and in dogs with hyperadrenocorticism
Authors: Melián Limiñana, Carlos 
Pérez López, Laura Del Carmen 
Saavedra Santana, Pedro 
Ravelo García, Antonio Gabriel 
Santos, Yaiza
Jáber Mohamad, José Raduán 
UNESCO Clasification: 310904 Medicina interna
320502 Endocrinología
Keywords: Adrenal gland
Ultrasound evaluation
Issue Date: 2021
Journal: Veterinary Record 
Abstract: Background: Precise reference intervals of adrenal gland thickness are required for detection of adrenomegaly in dogs with hyperadrenocorticism (HAC). Methods: Eighty-six clinically healthy dogs were prospectively included, and 91 dogs with untreated HAC were retrospectively evaluated. Dorso-ventral adrenal gland thickness was ultrasonographically measured on the sagittal plane. Dogs were classified into four body weight categories, and those with HAC were also ultrasonographically classified as consistent with pituitary-dependent HAC (PDH), adrenal-dependent HAC (FAT), equivocal adrenal asymmetry (EAA), or normal adrenal thickness. Results: The upper limits for left adrenal gland in clinically healthy dogs were 5.1 mm (≥2.5–5 kg), 5.5 mm (>5–10 kg), 6.4 mm (>10–20 kg), and 7.3 mm (>20–40 kg), and for right adrenal gland the upper limits were 5.3 mm (≥2.5–5 kg), 6.8 mm (>5–10 kg), 7.5 mm (>10–20 kg), and 8.7 mm (>20–40 kg). The sensitivity of ultrasound to detect adrenomegaly in dogs with HAC was 95.6%. Most dogs with HAC (56.0%) had ultrasound findings consistent with either PDH or FAT; however, EAA was commonly occurring in 39.6% of dogs with HAC. Conclusions: The sensitivity of ultrasonography to detect adrenomegaly in dogs with HAC is high when using four weight categories. EAA is common in dogs with HAC.
ISSN: 0042-4900
DOI: 10.1002/vetr.80
Source: Veterinary Record [ISSN 0042-4900], v. 188 (8), e80, (Abril 2021)
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