Please use this identifier to cite or link to this item:
http://hdl.handle.net/10553/106635
DC Field | Value | Language |
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dc.contributor.author | Gutiérrez Falcón, Ana Isabel | - |
dc.contributor.author | Ramos-Nuez, A. M. | - |
dc.contributor.author | Espinosa De Los Monteros Y Zayas, Antonio | - |
dc.contributor.author | Padilla Castillo, Daniel Fermín | - |
dc.contributor.author | García-Laorden, M. Isabel | - |
dc.contributor.author | Chamizo-López, F. J. | - |
dc.contributor.author | Real Valcárcel, Fernando | - |
dc.contributor.author | Campelo, F. Artilles | - |
dc.contributor.author | Benítez, A. Bordes | - |
dc.contributor.author | Salgueiro, P. Nogueira | - |
dc.contributor.author | Cabrera, C. Domínguez | - |
dc.contributor.author | Rivero-Vera, J. C. | - |
dc.contributor.author | González-Martín, J. M. | - |
dc.contributor.author | Caballero, J. Martín | - |
dc.contributor.author | Frías-Beneyto, R. | - |
dc.contributor.author | Villar, Jesús | - |
dc.contributor.author | Martín Barrasa, José Luis | - |
dc.date.accessioned | 2021-04-08T12:59:48Z | - |
dc.date.available | 2021-04-08T12:59:48Z | - |
dc.date.issued | 2021 | - |
dc.identifier.issn | 1867-1306 | - |
dc.identifier.other | Scopus | - |
dc.identifier.uri | http://hdl.handle.net/10553/106635 | - |
dc.description.abstract | A strain of Alcaligenes faecalis A12C (A. faecalis A12C) isolated from Argyrosomus regius is a probiotic in fish. Previous experiments showed that A. faecalis A12C had inhibitory effects on the growth of multidrug-resistant bacteria. We aimed to confirm whether A. faecalis A12C is safe and has adequate intestinal colonization in experimental rats, and evaluate its efficacy in an animal model of peritonitis. We used 30 male rats, randomly divided into 6 groups (n = 5): three groups (HA7, HA15, HA30) received A. faecalis A12C in drinking water (6 × 108 CFU/mL) for 7 days, and three control groups received drinking water only. All groups were evaluated at 7, 15, and 30 days. Survival after A. faecalis A12C administration was 100% in all groups. Mild eosinophilia (1.5%, p < 0.01) and increased aspartate aminotransferase (86 IU/L, p < 0.05) were observed in HA7, followed by progressive normalization. No histological signs of organ injury were found. We observed significant E. coli decline in faeces, parallel to an increase in A. faecalis A12C at 7 days. E. coli had a tendency to recover initial values, while A. faecalis A12C disappeared from the intestinal microbiota at 30 days. To evaluate its efficacy against peritonitis, we studied two additional groups of animals: IA group pretreated with A. faecalis A12C before E. coli intra-abdominal inoculation, and IC group inoculated with no A. faecalis A12C. We found an increase in C-reactive protein, alanine aminotransferase, urea, and eosinophils in IC animals when compared with IA. Peritonitis was more evident in IC than in IA animals. Our findings suggest that A. faecalis A12C altered clinically relevant parameters in sepsis and was associated with a lesser spread of infection. | - |
dc.language | eng | - |
dc.relation | Nuevos Priobioticos y Sus Productos Para El Control de Enfermedades en Especies Relevantes Pra la Acuicultura Marina y Continental | - |
dc.relation | PIFULPGC-2015-CCSALUD | - |
dc.relation.ispartof | Probiotics and Antimicrobial Proteins | - |
dc.source | Probiotics and Antimicrobial Proteins [ISSN 1867-1306], n. 13, p. 1326–1337 | - |
dc.subject | 310905 Microbiología | - |
dc.subject | 310801 Bacterias | - |
dc.subject.other | Alcaligenes Faecalis | - |
dc.subject.other | Argyrosomus Regius | - |
dc.subject.other | Escherichia Coli | - |
dc.subject.other | Peritonitis | - |
dc.subject.other | Probiotic | - |
dc.subject.other | Rat | - |
dc.title | Probiotic Properties of Alcaligenes faecalis Isolated from Argyrosomus regius in Experimental Peritonitis (Rat Model) | - |
dc.type | info:eu-repo/semantics/Article | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s12602-021-09767-7 | - |
dc.identifier.pmid | 33713309 | - |
dc.identifier.scopus | 85102696885 | - |
dc.identifier.isi | WOS:000628463200001 | - |
dc.contributor.orcid | 0000-0002-2672-9356 | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | 0000-0002-7736-3139 | - |
dc.contributor.orcid | 0000-0002-6678-5029 | - |
dc.contributor.orcid | 0000-0001-6270-6306 | - |
dc.contributor.orcid | 0000-0003-1328-1924 | - |
dc.contributor.orcid | 0000-0001-6526-0354 | - |
dc.contributor.orcid | 0000-0003-3019-8604 | - |
dc.contributor.orcid | 0000-0003-3243-7402 | - |
dc.contributor.orcid | 0000-0002-8029-2685 | - |
dc.contributor.orcid | 0000-0003-2600-1637 | - |
dc.contributor.orcid | #NODATA# | - |
dc.contributor.orcid | 0000-0001-6816-4157 | - |
dc.contributor.orcid | 0000-0002-1579-2739 | - |
dc.contributor.orcid | 0000-0001-7569-5693 | - |
dc.contributor.orcid | 0000-0001-5687-3562 | - |
dc.contributor.orcid | 0000-0002-3280-9838 | - |
dc.contributor.authorscopusid | 57219965398 | - |
dc.contributor.authorscopusid | 55480754700 | - |
dc.contributor.authorscopusid | 57222432938 | - |
dc.contributor.authorscopusid | 57222426388 | - |
dc.contributor.authorscopusid | 6506073949 | - |
dc.contributor.authorscopusid | 54792621800 | - |
dc.contributor.authorscopusid | 57222431140 | - |
dc.contributor.authorscopusid | 57222428166 | - |
dc.contributor.authorscopusid | 36338524500 | - |
dc.contributor.authorscopusid | 57222429600 | - |
dc.contributor.authorscopusid | 57222432144 | - |
dc.contributor.authorscopusid | 6508341920 | - |
dc.contributor.authorscopusid | 57203435427 | - |
dc.contributor.authorscopusid | 57222426862 | - |
dc.contributor.authorscopusid | 57222430811 | - |
dc.contributor.authorscopusid | 55236061500 | - |
dc.contributor.authorscopusid | 6506508811 | - |
dc.identifier.eissn | 1867-1314 | - |
dc.identifier.issue | 5 | - |
dc.investigacion | Ciencias de la Salud | - |
dc.type2 | Artículo | - |
dc.utils.revision | Sí | - |
dc.identifier.ulpgc | Sí | - |
dc.contributor.buulpgc | BU-VET | - |
dc.description.sjr | 0,812 | - |
dc.description.jcr | 5,265 | - |
dc.description.sjrq | Q2 | - |
dc.description.jcrq | Q2 | - |
dc.description.scie | SCIE | - |
dc.description.miaricds | 10,6 | - |
item.grantfulltext | none | - |
item.fulltext | Sin texto completo | - |
crisitem.author.dept | GIR IUSA-ONE HEALTH 2 - Sanidad Animal de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas y Seguridad Alimentaria | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | GIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina) | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Morfología | - |
crisitem.author.dept | GIR IUSA-ONE HEALTH 2 - Sanidad Animal de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas y Seguridad Alimentaria | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.dept | GIR IUSA-ONE HEALTH 2 - Sanidad Animal de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas y Seguridad Alimentaria | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.dept | GIR IUSA-ONE HEALTH 2 - Sanidad Animal de la Acuicultura y Especies Silvestres, Enfermedades Infecciosas y Seguridad Alimentaria | - |
crisitem.author.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.dept | Departamento de Patología Animal, Producción Animal, Bromatología y Tecnología de Los Alimentos | - |
crisitem.author.orcid | 0000-0002-7736-3139 | - |
crisitem.author.orcid | 0000-0002-6678-5029 | - |
crisitem.author.orcid | 0000-0001-6526-0354 | - |
crisitem.author.orcid | 0000-0002-3280-9838 | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.parentorg | IU de Sanidad Animal y Seguridad Alimentaria | - |
crisitem.author.fullName | Gutiérrez Falcón,Ana | - |
crisitem.author.fullName | Espinosa De Los Monteros Y Zayas, Antonio | - |
crisitem.author.fullName | Padilla Castillo, Daniel Fermín | - |
crisitem.author.fullName | Real Valcárcel, Fernando | - |
crisitem.author.fullName | Martín Barrasa, José Luis | - |
crisitem.project.principalinvestigator | Real Valcárcel, Fernando | - |
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