Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/105838
DC FieldValueLanguage
dc.contributor.authorSamarasinghe, M.B.en_US
dc.contributor.authorSehested, J.en_US
dc.contributor.authorLarsen, T.en_US
dc.contributor.authorHernández Castellano, Lorenzo Enriqueen_US
dc.date.accessioned2021-03-17T11:15:36Z-
dc.date.available2021-03-17T11:15:36Z-
dc.date.issued2020en_US
dc.identifier.issn0022-0302en_US
dc.identifier.urihttp://hdl.handle.net/10553/105838-
dc.description.abstractIt is well established that intravenous administration of lipopolysaccharides (LPS)-cell wall components from gram-negative bacteria-induce acute inflammatory responses in dairy calves, but the effect of oral administration of LPS to dairy calves is currently unknown. To evaluate the effects of oral administration of LPS derived from Escherichia coli (serotype O111:B4) on innate immune responses in milk-fed Holstein calves, 20 visually healthy calves (34 ± 1 d) received 4 L of milk with LPS (12 μg/kg body weight; n = 10; LPS) or without LPS (n = 10; control) at the morning feeding. Samples were collected at 0.5 h before the morning feeding and at 3, 6, 24, 48, 72, and 168 h after the morning feeding to measure rectal temperature and heart rate, as well as plasma-negative and plasma-positive acute phase proteins (i.e., haptoglobin, serum amyloid A, albumin, total protein, and fibrinogen) and immunoglobulin concentrations (IgG, IgM, and IgA). None of these measurements was affected by the oral administration of LPS. Oral administration of LPS at 12 μg/kg of body weight did not induce an acute inflammatory response in visually healthy milk-fed Holstein calves when administered in milk.en_US
dc.languageengen_US
dc.relation.ispartofJournal of Dairy Scienceen_US
dc.sourceJournal of Dairy Science [ISSN 0022-0302], v. 103(6), p. 5525-5531en_US
dc.subject3104 Producción Animalen_US
dc.subject310907 Patologíaen_US
dc.subject310903 Inmunologíaen_US
dc.subject.otherEscherichia colien_US
dc.subject.otherCalvesen_US
dc.subject.otherImmune systemen_US
dc.subject.otherLipopolysaccharidesen_US
dc.titleOral administration of lipopolysaccharides from Escherichia coli (serotype O111:B4) does not induce an effective systemic immune response in milk-fed Holstein calvesen_US
dc.typeinfo:eu-repo/semantics/articleen_US
dc.typeArticleen_US
dc.identifier.doi10.3168/jds.2019-17404en_US
dc.description.lastpage5531en_US
dc.identifier.issue6-
dc.description.firstpage5525en_US
dc.relation.volume103en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.utils.revisionen_US
dc.identifier.ulpgcNoen_US
dc.contributor.buulpgcBU-VETen_US
dc.description.sjr1,483
dc.description.jcr4,034
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.author.deptGIR IUSA-ONEHEALTH 4. Producción y Biotecnología Animal-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.orcid0000-0003-2729-0434-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.fullNameHernández Castellano, Lorenzo Enrique-
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