Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/101169
Campo DC Valoridioma
dc.contributor.advisorJáber Mohamad, José Raduán-
dc.contributor.advisorSuárez Bonnet, Alejandro-
dc.contributor.authorParéns González, Lucía-
dc.date.accessioned2021-03-11T00:50:22Z-
dc.date.available2021-03-11T00:50:22Z-
dc.date.issued2019en_US
dc.identifier.otherGestión académica
dc.identifier.urihttp://hdl.handle.net/10553/101169-
dc.description.abstractAfrican green monkey (Chlorocebus pygerythrus) is a non-human primate (NHP) and a pivotal model in biomedical research. Spontaneous neoplasms in NHP are rarely reported and only sporadic descriptions have been published. Herein we describe a unique case of metastatic cholangiocarcinoma with concurrent abdominal cestodiasis in an African green monkey, which presented with respiratory insufficiency and abdominal discomfort. An exploratory laparotomy revealed multiple white-grey masses in the liver and colonic serosa alongside with intra-abdominal parasitic cysts. Histologically, the liver masses were composed of poorly-differentiated epithelial cells that formed dense solid areas and trabeculae. An identical microscopic appearance was observed in the lung and colonic lesions. Immunohistochemically neoplastic cells were strongly positive for anti-CK-7 and negative for anti-Hep-Par1 antibodies, which revealed a cholangiocarcinoma. Interestingly the neoplasm strongly expressed 14-3-3-sigma and E-cadherin. Furthermore the histological characteristics of the parasite larvae were consistent with Mesocestoides spp. To the author´s knowledge, this is the first description of a metastatic cholangiocarcinoma with concurrent abdominal cestodiasis in an African green monkey.en_US
dc.languageengen_US
dc.subject310907 Patologíaen_US
dc.subject310901 Anatomíaen_US
dc.subject240121 Primatesen_US
dc.subject241202 Anticuerposen_US
dc.subject.otherabdominal cestodiasisen_US
dc.subject.othercholangiocarcinomaen_US
dc.subject.otherimmunhistochemistryen_US
dc.subject.othervervet monkeyen_US
dc.titleMetastatic cholangiocarcinoma in association with abdominal Cestodiasis in a vervet monkey (Chlorocebus pygerythrus)en_US
dc.typeinfo:eu-repo/semantics/bachelorThesisen_US
dc.typeBachelorThesisen_US
dc.contributor.departamentoDepartamento de Morfologíaen_US
dc.contributor.facultadFacultad de Veterinariaen_US
dc.investigacionCiencias de la Saluden_US
dc.type2Trabajo final de gradoen_US
dc.utils.revisionen_US
dc.identifier.matriculaTFT-52091es
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-VETen_US
dc.contributor.titulacionGrado en Veterinariaes
item.grantfulltextnone-
item.fulltextSin texto completo-
crisitem.advisor.deptGIR Anatomía Aplicada y Herpetopatología-
crisitem.advisor.deptDepartamento de Morfología-
crisitem.advisor.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.advisor.deptIU de Sanidad Animal y Seguridad Alimentaria-
Colección:Trabajo final de grado
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