Identificador persistente para citar o vincular este elemento:
http://hdl.handle.net/10553/101169
Campo DC | Valor | idioma |
---|---|---|
dc.contributor.advisor | Jáber Mohamad, José Raduán | - |
dc.contributor.advisor | Suárez Bonnet, Alejandro | - |
dc.contributor.author | Paréns González, Lucía | - |
dc.date.accessioned | 2021-03-11T00:50:22Z | - |
dc.date.available | 2021-03-11T00:50:22Z | - |
dc.date.issued | 2019 | en_US |
dc.identifier.other | Gestión académica | |
dc.identifier.uri | http://hdl.handle.net/10553/101169 | - |
dc.description.abstract | African green monkey (Chlorocebus pygerythrus) is a non-human primate (NHP) and a pivotal model in biomedical research. Spontaneous neoplasms in NHP are rarely reported and only sporadic descriptions have been published. Herein we describe a unique case of metastatic cholangiocarcinoma with concurrent abdominal cestodiasis in an African green monkey, which presented with respiratory insufficiency and abdominal discomfort. An exploratory laparotomy revealed multiple white-grey masses in the liver and colonic serosa alongside with intra-abdominal parasitic cysts. Histologically, the liver masses were composed of poorly-differentiated epithelial cells that formed dense solid areas and trabeculae. An identical microscopic appearance was observed in the lung and colonic lesions. Immunohistochemically neoplastic cells were strongly positive for anti-CK-7 and negative for anti-Hep-Par1 antibodies, which revealed a cholangiocarcinoma. Interestingly the neoplasm strongly expressed 14-3-3-sigma and E-cadherin. Furthermore the histological characteristics of the parasite larvae were consistent with Mesocestoides spp. To the author´s knowledge, this is the first description of a metastatic cholangiocarcinoma with concurrent abdominal cestodiasis in an African green monkey. | en_US |
dc.language | eng | en_US |
dc.subject | 310907 Patología | en_US |
dc.subject | 310901 Anatomía | en_US |
dc.subject | 240121 Primates | en_US |
dc.subject | 241202 Anticuerpos | en_US |
dc.subject.other | abdominal cestodiasis | en_US |
dc.subject.other | cholangiocarcinoma | en_US |
dc.subject.other | immunhistochemistry | en_US |
dc.subject.other | vervet monkey | en_US |
dc.title | Metastatic cholangiocarcinoma in association with abdominal Cestodiasis in a vervet monkey (Chlorocebus pygerythrus) | en_US |
dc.type | info:eu-repo/semantics/bachelorThesis | en_US |
dc.type | BachelorThesis | en_US |
dc.contributor.departamento | Departamento de Morfología | en_US |
dc.contributor.facultad | Facultad de Veterinaria | en_US |
dc.investigacion | Ciencias de la Salud | en_US |
dc.type2 | Trabajo final de grado | en_US |
dc.utils.revision | Sí | en_US |
dc.identifier.matricula | TFT-52091 | es |
dc.identifier.ulpgc | Sí | en_US |
dc.contributor.buulpgc | BU-VET | en_US |
dc.contributor.titulacion | Grado en Veterinaria | es |
item.grantfulltext | none | - |
item.fulltext | Sin texto completo | - |
crisitem.advisor.dept | GIR Anatomía Aplicada y Herpetopatología | - |
crisitem.advisor.dept | Departamento de Morfología | - |
crisitem.advisor.dept | GIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina) | - |
crisitem.advisor.dept | IU de Sanidad Animal y Seguridad Alimentaria | - |
Colección: | Trabajo final de grado |
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