Identificador persistente para citar o vincular este elemento: http://hdl.handle.net/10553/43428
Campo DC Valoridioma
dc.contributor.authorMestrón, Antonioen_US
dc.contributor.authorWebb, Susan M.en_US
dc.contributor.authorAstorga, Ricardoen_US
dc.contributor.authorBenito, Pedroen_US
dc.contributor.authorCatalá, Miguelen_US
dc.contributor.authorGaztambide, Soniaen_US
dc.contributor.authorGómez, José Manuelen_US
dc.contributor.authorHalperín, Ireneen_US
dc.contributor.authorLucas-Morante, Tomásen_US
dc.contributor.authorMoreno, Basilioen_US
dc.contributor.authorObiols, Gabrielen_US
dc.contributor.authorde Pablos, Pedroen_US
dc.contributor.authorPáramo, Conchaen_US
dc.contributor.authorPicó, Antonioen_US
dc.contributor.authorTorres, Elenaen_US
dc.contributor.authorVarela, Césaren_US
dc.contributor.authorVázquez, José Antonioen_US
dc.contributor.authorZamora, Juanaen_US
dc.contributor.authorAlbareda, Mercèen_US
dc.contributor.authorGilabert, Montserraten_US
dc.contributor.authorSánchez-Covisa, Miguel Aguirreen_US
dc.contributor.authorAlcaraz Tafalla, Marisolen_US
dc.contributor.authorAlonso Troncoso, Isabelen_US
dc.contributor.authorÁlvarez Escolà, Cristinaen_US
dc.contributor.authorAndía Melero, Victor Manuelen_US
dc.contributor.authorArranz Martín, Alfonsoen_US
dc.contributor.authorArribas Palomar, Luisen_US
dc.contributor.authorBallesteros Pomar, Maríaen_US
dc.contributor.authorBeitia Martín, Juan Joséen_US
dc.contributor.authorLópez, Pedro Benitoen_US
dc.contributor.authorBernabeu Morón, Ignacioen_US
dc.contributor.authorBlanco Carrera, Concepciónen_US
dc.contributor.authorBlanco Samper, Benitoen_US
dc.contributor.authorBoronat Cortés, Mauroen_US
dc.contributor.authorCarrera Santaliestra, Maria Joséen_US
dc.contributor.authorCastillo López, Luisen_US
dc.contributor.authorCordero Diez, Ma del Maren_US
dc.contributor.authorCostilla Martín, Enriqueen_US
dc.contributor.authorCózar León, Ma Victoriaen_US
dc.contributor.authorCuatrecasas Cambra, Guillemen_US
dc.contributor.authorDe Luís Román, Daniel Antonioen_US
dc.contributor.authorde Miguel Novoa, Ma Pazen_US
dc.contributor.authorDe Pablos Velasco, Pedro Luisen_US
dc.contributor.authorDel Pozo Picó, Carlosen_US
dc.contributor.authorDiez Gómez, Juan Joséen_US
dc.contributor.authorDíez Hernández, Albertoen_US
dc.contributor.authorDuran Rodríguez-Hervada, Alejandraen_US
dc.contributor.authorde Antonio, Isabel Estevaen_US
dc.contributor.authorFajardo Montañana, Carmenen_US
dc.contributor.authorForga Llenas, Lluísen_US
dc.contributor.authorFraile Saez, Ángel Luisen_US
dc.contributor.authorGalvez Moreno, Ma Angelesen_US
dc.contributor.authorGarcía Centera, José Andrésen_US
dc.contributor.authorGargallo Fernández, Manuelen_US
dc.contributor.authorGavilán Villarejo, Inmaculadaen_US
dc.contributor.authorGil del Álamo, Palomaen_US
dc.contributor.authorGilsanz Peral, Albertoen_US
dc.contributor.authorGippini Pérez, Antonioen_US
dc.contributor.authorGómez Balaguer, Marcelinoen_US
dc.contributor.authorGómez, Luis Albertoen_US
dc.contributor.authorGorgojo Martínez, Juan Joséen_US
dc.contributor.authorGuerrero Martínez, Eduardoen_US
dc.contributor.authorHernández Bayo, Juan Angelen_US
dc.contributor.authorHernández López, Antonioen_US
dc.contributor.authorIglesias, Pedroen_US
dc.contributor.authorIllán Gómez, Fátimaen_US
dc.contributor.authorJaunsolo Barranechea, Miguel Ángelen_US
dc.contributor.authorLecube Torelló, Alberten_US
dc.contributor.authorLiante Peñambía, Gasparen_US
dc.contributor.authorLópez dela Torre Casares, Martinen_US
dc.contributor.authorLópez Hernández, Elenaen_US
dc.contributor.authorLópez López, Joséen_US
dc.contributor.authorLópez-Guzmán, Antonioen_US
dc.contributor.authorLucas Martín, Anaen_US
dc.contributor.authorMarazuela Azpiroz, Mónicaen_US
dc.contributor.authorMarco Martínez, Amparoen_US
dc.contributor.authorMarco Mur, Ángel Luisen_US
dc.contributor.authorMartin Castillo, Fidelen_US
dc.contributor.authorMartín González, Tomásen_US
dc.contributor.authorMartínez Brocca, Maria Asuncióen_US
dc.contributor.authorMegia Colet, Anaen_US
dc.contributor.authorMerino Torres, Juan Franciscoen_US
dc.contributor.authorMorales Gorría, Ma Joséen_US
dc.contributor.authorMorales Perez, Franciscoen_US
dc.contributor.authorMurillo Sanchis, Jesúsen_US
dc.contributor.authorMuros de Fuentes, Ma Teresaen_US
dc.contributor.authorPáramo Fernández, Concepciónen_US
dc.contributor.authorPavón de Paz, Isabelen_US
dc.contributor.authorPazos Toral, Fernandoen_US
dc.contributor.authorPérez Corral, Ma Begoñaen_US
dc.contributor.authorPérez Pérez, Antonioen_US
dc.contributor.authorPi Barrio, J. Javieren_US
dc.contributor.authorPiedrola Morato, Gonzaloen_US
dc.contributor.authorPou Torelló, José Maen_US
dc.contributor.authorPuigdevall Gallego, Victoren_US
dc.contributor.authorRodríguez Guerrero, Palomaen_US
dc.contributor.authorRodríguez Roble, Azuzenaen_US
dc.contributor.authorRomero Bobillo, Enriqueen_US
dc.contributor.authorRuano Vieitez, Belénen_US
dc.date.accessioned2018-11-21T15:05:07Z-
dc.date.available2018-11-21T15:05:07Z-
dc.date.issued2004en_US
dc.identifier.issn0804-4643en_US
dc.identifier.urihttp://hdl.handle.net/10553/43428-
dc.description.abstractObjective: To undertake a multicentre epidemiological study reflecting acromegaly in Spain. Design: Voluntary reporting of data on patients with acromegaly to an online database, by the managing physician. Methods: Data on demographics, diagnosis, estimated date of initial symptoms and diagnosis, pituitary imaging, visual fields, GH and IGF-I concentrations (requested locally), medical, radiotherapy and neurosurgical treatments, morbidity and mortality were collected. Results: Data were included for 1219 patients (60.8% women) with a mean age at diagnosis of 45 years (S.D. 14 years). Reporting was maximal in 1997 (2.1 cases per million inhabitants (c.p.m.) per year); prevalence was globally 36 c.p.m., but varied between 15.7 and 75.8 c.p.m. in different regions. Of 1196 pituitary tumours, most were macroadenomas (73%); 81% of these patients underwent surgery, 45% received radiotherapy and 65% were given medical treatment (somatostatin analogues in 68.3% and dopamine agonists in 31.4%). Cures (GH values (basal or after an oral glucose tolerance test) ,2 ng/ml, normal IGF-I, or both) were observed in 40.3% after surgery and 28.2% after radiotherapy. Hypertension (39.1%), diabetes mellitus (37.6%), hypopituitarism (25.7%), goitre (22.4%), carpal tunnel syndrome (18.7%) and sleep apnoea (13.2%) were reported as most frequent morbidities; 6.8% of the patients had cancer (breast in 3.1% of the women and colon in 1.2% of the cohort). Fifty-six patients died at a mean age of 60 years (S.D. 14 years), most commonly of a cardiovascular cause (39.4%); mortality was greater in patients given radiotherapy (hazard ratio 2.29; 95% confidence interval 1.03 to 5.08; P ¼ 0.026), and in those in whom GH and IGF-I concentrations were never normal (P , 0.001). Conclusions: This acromegaly registry offers a realistic overview of the epidemiological characteristics, treatment outcome and morbidity of acromegaly in Spain. As active disease and treatment with radiotherapy are associated with an increase in mortality, efforts to control the disease early are desirable.en_US
dc.languageengen_US
dc.publisher0804-4643-
dc.relation.ispartofEuropean Journal of Endocrinologyen_US
dc.sourceEuropean Journal of Endocrinology [ISSN 0804-4643], v. 151, p. 439-446en_US
dc.subject32 Ciencias médicasen_US
dc.titleEpidemiology, clinical characteristics, outcome, morbidity and mortality in acromegaly based on the Spanish Acromegaly Registry (Registro Español de Acromegalia, REA)en_US
dc.typeinfo:eu-repo/semantics/reviewes
dc.typeArticlees
dc.identifier.doi10.1530/eje.0.1510439-
dc.identifier.scopus7244257406-
dc.contributor.authorscopusid6506205045-
dc.contributor.authorscopusid7402907929-
dc.contributor.authorscopusid7006637866-
dc.contributor.authorscopusid7005691601-
dc.contributor.authorscopusid57196475447-
dc.contributor.authorscopusid6601967212-
dc.contributor.authorscopusid34770414700-
dc.contributor.authorscopusid7006053764-
dc.contributor.authorscopusid6602722752-
dc.contributor.authorscopusid7004888145-
dc.contributor.authorscopusid6602533540-
dc.contributor.authorscopusid6602664493-
dc.contributor.authorscopusid6701587192-
dc.contributor.authorscopusid56954703100-
dc.contributor.authorscopusid7101808498-
dc.contributor.authorscopusid7006081205-
dc.contributor.authorscopusid56822964800-
dc.contributor.authorscopusid7007126312-
dc.contributor.authorscopusid6603639843-
dc.contributor.authorscopusid56259724300-
dc.contributor.authorscopusid6505584032-
dc.contributor.authorscopusid55177325200-
dc.contributor.authorscopusid6507256699-
dc.contributor.authorscopusid22633901700-
dc.contributor.authorscopusid6507444443-
dc.contributor.authorscopusid6507804239-
dc.contributor.authorscopusid6506203449-
dc.contributor.authorscopusid55923812200-
dc.contributor.authorscopusid6507320035-
dc.contributor.authorscopusid56262704100-
dc.contributor.authorscopusid6505626122-
dc.contributor.authorscopusid56635423800-
dc.contributor.authorscopusid6505779661-
dc.contributor.authorscopusid21736048400-
dc.contributor.authorscopusid7801532866-
dc.contributor.authorscopusid6507059695-
dc.contributor.authorscopusid6504693642-
dc.contributor.authorscopusid6503889048-
dc.contributor.authorscopusid6504208512-
dc.contributor.authorscopusid6505575256-
dc.contributor.authorscopusid7006033864-
dc.contributor.authorscopusid6507880850-
dc.contributor.authorscopusid6603805479-
dc.contributor.authorscopusid6507436670-
dc.contributor.authorscopusid6508035039-
dc.contributor.authorscopusid6507772842-
dc.contributor.authorscopusid6505667578-
dc.contributor.authorscopusid6506196421-
dc.contributor.authorscopusid6507871833-
dc.contributor.authorscopusid6602987832-
dc.contributor.authorscopusid6507200582-
dc.contributor.authorscopusid6507038066-
dc.contributor.authorscopusid6505597195-
dc.contributor.authorscopusid6602442938-
dc.contributor.authorscopusid6603546375-
dc.contributor.authorscopusid6603501664-
dc.contributor.authorscopusid6602721487-
dc.contributor.authorscopusid6506733022-
dc.contributor.authorscopusid35575659100-
dc.contributor.authorscopusid7202331899-
dc.contributor.authorscopusid6507483772-
dc.contributor.authorscopusid56157986500-
dc.contributor.authorscopusid57199572342-
dc.contributor.authorscopusid57052954400-
dc.contributor.authorscopusid7006659849-
dc.contributor.authorscopusid6603266852-
dc.contributor.authorscopusid6505478062-
dc.contributor.authorscopusid6508264775-
dc.contributor.authorscopusid6504568221-
dc.contributor.authorscopusid6504524583-
dc.contributor.authorscopusid6603315583-
dc.contributor.authorscopusid57197878936-
dc.contributor.authorscopusid6701834423-
dc.contributor.authorscopusid6701755088-
dc.contributor.authorscopusid7004723223-
dc.contributor.authorscopusid6507723312-
dc.contributor.authorscopusid6507905090-
dc.contributor.authorscopusid6507621954-
dc.contributor.authorscopusid57188562747-
dc.contributor.authorscopusid6507049727-
dc.contributor.authorscopusid9336204300-
dc.contributor.authorscopusid6602824949-
dc.contributor.authorscopusid7801549596-
dc.contributor.authorscopusid56128275500-
dc.contributor.authorscopusid6508293179-
dc.contributor.authorscopusid6601975594-
dc.contributor.authorscopusid6506697310-
dc.contributor.authorscopusid6603258314-
dc.contributor.authorscopusid6506498792-
dc.contributor.authorscopusid6508081183-
dc.contributor.authorscopusid57198021538-
dc.contributor.authorscopusid15770121700-
dc.contributor.authorscopusid6505632705-
dc.contributor.authorscopusid6602794859-
dc.contributor.authorscopusid6602529370-
dc.contributor.authorscopusid6503850647-
dc.contributor.authorscopusid6504660675-
dc.contributor.authorscopusid6602522216-
dc.contributor.authorscopusid6504759972-
dc.description.lastpage446-
dc.description.firstpage439-
dc.relation.volume151-
dc.investigacionCiencias de la Saluden_US
dc.type2Reseñaen_US
dc.identifier.ulpgces
dc.description.jcr3,14
dc.description.jcrqQ2
dc.description.scieSCIE
item.fulltextSin texto completo-
item.grantfulltextnone-
crisitem.author.deptGIR IUIBS: Diabetes y endocrinología aplicada-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.deptGIR IUIBS: Rendimiento humano, ejercicio físico y salud-
crisitem.author.deptIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.deptDepartamento de Ciencias Médicas y Quirúrgicas-
crisitem.author.orcid0000-0001-8535-8543-
crisitem.author.orcid0000-0002-9190-2581-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.parentorgIU de Investigaciones Biomédicas y Sanitarias-
crisitem.author.fullNameBoronat Cortés, Mauro-
crisitem.author.fullNameDe Pablos Velasco, Pedro Luis-
Colección:Reseña
Vista resumida

Citas SCOPUSTM   

320
actualizado el 24-mar-2024

Visitas

105
actualizado el 23-mar-2024

Google ScholarTM

Verifica

Altmetric


Comparte



Exporta metadatos



Los elementos en ULPGC accedaCRIS están protegidos por derechos de autor con todos los derechos reservados, a menos que se indique lo contrario.