Vulvovaginal squamous cell carcinoma on female dog. Literature review,comparative aspects and case reports

Abstract

Vulvovaginal squamous cell carcinoma is a rare malignant tumor in female dogs, not published in the literature. However, between 2011 and 2017 the GICOREC-IUSA oncology service received three patients with this type of tumor. Currently, vulvovaginal SCC is the object of study in women, with whom we have found similarities with respect to clinical presentation and tumor behavior, which allows us to study the diagnostic and staging protocols, and treatment, being able to establish a more accurate prognosis. The main treatment of our patients consisted of surgical exeresis of the tumor trying to leave free-tumor cells margins, without knowing its stage or if the patient needed adjuvant therapy; so, special importance was given to the diagnosis protocol and stage of the disease in order to improve the OS of our patients by administering the appropriate treatment. In women surgical treatment is performed together with adjuvant therapy in patients who present VaIN, VIN, or stage I of vulvovaginal SCC; In veterinary medicine, a reliable staging for this type of tumor on female dogs has not been developed, so we do not know if it had an influence on the fact that the treatment used did not cure any of the patients despite there were significant differences between our patients on their FDI and OS.