Persistence of Glycemia after oral administration of Propylene Glycol in goats. A clinical trial.

Abstract

Toxemia of pregnancy is a metabolic disorder that occurs in small ruminants during the last phase of pregnancy. Pregnant animals with low energy levels and multiple fetuses are more susceptible to toxemia. Propylene glycol (PG) could be a useful preventive therapeutic plan for this disease. This clinical trial evaluates the persistence levels of glycaemia after the administration of two different doses (30 mL and 60 mL) of PG, as well as the persistence of hyperglycemia. This study was carried out with 13 goats between 4-5 years, during the drying period. Blood samples were taken from the animals before and after PG administration. It is concluded that the use of PG at high doses can be used to improve glycaemia without causing unwanted adverse effects. The glucose peak is visible at 150 minutes; after which it starts to decrease. There is no significant difference in glucose when 30 mL or 60 mL of PG is given