Estévez Rosas, Francisco Jesús

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Relaciones estructura-actividad de 1,3-difenilpropenonas revelan un potente inhibidor de la polimerización de tubulina del Rosario, Henoc; Saavedra, Ester; Brouard Martín,Ignacio; González Santana, Daniel; García, Celina, et al Issued date: 2023 Póster de congresos
Flavonoid Derivative FMC, as a Potent Cytotoxic and Apoptosis Inducer in Several Human Cancer Cell Lines del Rosario, Henoc; Saavedra, Ester; Brouard Martín,Ignacio; González Santana, Daniel; García, Celina, et al Issued date: 2023 Source: III Bio.Natural: bioactive natural products research meeting 2023. Abstract book Póster de congresos
Chemical-proteomics Identify Peroxiredoxin-1 as an Actionable Target in Triple-negative Breast Cancer Spinola Lasso, Elena; Montero, Juan Carlos; Jiménez Monzón,Roberto; Estévez Rosas, Francisco Jesús; Quintana Aguiar, José Martín Issued date: 2023 DOI: 10.7150/ijbs.78554 Source: International Journal of Biological Sciences [ISSN 1449-2288], v. 19(6), pp. 1731-1747 (Marzo 2023) SJR: 2,114 - Q1 JCR: 8,2 - Q1 SCIE MIAR ICDS: 10,7 Artículo
Structure-activity relationships reveal a 2-furoyloxychalcone as a potent cytotoxic and apoptosis inducer for human U-937 and HL-60 leukaemia cells Del Rosario García, Henoc; Saavedra Díaz, Ester Gloria; Brouard Martín,Ignacio; González-Santana, Daniel; García, Celina, et al Issued date: 2022 DOI: 10.1016/j.bioorg.2022.105926 Source: Bioorganic Chemistry [ISSN 0045-2068], v. 127, 105926, (Octubre 2022) SJR: 0,763 - Q1 JCR: 5,1 - Q1 SCIE MIAR ICDS: 11,0 Artículo
Guanidine Derivatives Containing the Chalcone Skeleton Are Potent Antiproliferative Compounds against Human Leukemia Cells Estévez Sarmiento,Francisco; Saavedra Díaz, Ester Gloria; Brouard Martín,Ignacio; Peyrac, Jesús; Hernández-Garcés, Judith, et al Issued date: 2022 DOI: 10.3390/ijms232415518 Source: International journal of molecular sciences [EISSN 1422-0067], v. 23 (24), 15518, (Diciembre 2022) SJR: 1,154 - Q1 JCR: 5,6 - Q1 SCIE MIAR ICDS: 10,8 Artículo
Design and synthesis of naphthylchalcones as novel anti-leukaemia agents Leitão, Emília P.T.; Ascenso, Osvaldo S.; Santos de Almeida, Tania; González, Ignacio; Hernández, Inmaculada Issued date: 2021 DOI: 10.1016/j.bioorg.2021.105348 Source: Bioorganic Chemistry [ISSN 0045-2068], v. 117, 105348, (Diciembre 2021) SJR: 0,728 - Q2 JCR: 5,307 - Q1 SCIE MIAR ICDS: 11,0 Artículo
Apoptosis pathways triggered by a potent antiproliferative hybrid chalcone on human melanoma cells Rodríguez, Irene; Saavedra Díaz, Ester Gloria; Del Rosario, Henoc; Perdomo Díaz, Juan; Quintana Aguiar, José Martín Issued date: 2021 DOI: 10.3390/ijms222413462 Source: International Journal of Molecular Sciences [ISSN 1661-6596], v. 22 (24), 13462, (Diciembre 2021) SJR: 1,176 - Q1 JCR: 6,208 - Q1 SCIE MIAR ICDS: 10,8 Artículo
Antiangiogenic treatment for hereditary haemorrhagic telanciectasia Olivares Torres, Rubén; Quintana Aguiar, José Martín; Estévez Rosas, Francisco Jesús Issued date: 2021 Póster de congresos
Ethanol enhances hyperthermia‐induced cell death in human leukemia cells Quintana, Mercedes; Saavedra Díaz, Ester Gloria; Del Rosario García, Henoc; González, Ignacio; Hernández González, Inmaculada Servanda Issued date: 2021 DOI: 10.3390/ijms22094948 Source: International Journal of Molecular Sciences [ISSN 1422-0067], v. 22(9), 4948, (Mayo 2021) SJR: 1,176 - Q1 JCR: 6,208 - Q1 SCIE MIAR ICDS: 10,8 Artículo
Synthesis and Biological Evaluation of 2-Substituted Benzyl-/Phenylethylamino-4-amino-5-aroylthiazoles as Apoptosis-Inducing Anticancer Agents Oliva, Paola; Onnis, Valentina; Balboni, Elisa; Hamel, Ernest; Estévez-Sarmiento, Francisco, et al Issued date: 2020 DOI: 10.3390/molecules25092177 Source: Molecules (Basel, Switzerland ) [EISSN 1420-3049], v. 25 (9), (Mayo 2020) SJR: 0,782 - Q1 JCR: 4,411 - Q2 SCIE Artículo
Chlorinated Guaiane-Type Sesquiterpene Lactones as Cytotoxic Agents against Human Tumor Cells Estévez Sarmiento, Francisco; Saavedra Díaz, Ester Gloria; Mercedes Ruiz-Estévez; Francisco León; Quintana Aguiar, José Martín Issued date: 2020 DOI: 10.3390/ijms21249767 Source: International Journal of Molecular Sciences [EISSN 1422-0067], v. 21 (24), 9767 (Diciembre. 2020) SJR: 1,455 - Q1 JCR: 5,923 - Q1 SCIE Artículo
Cytotoxicity of the Sesquiterpene Lactone Spiciformin and Its Acetyl Derivative against the Human Leukemia Cell Lines U-937 and HL-60 Saavedra Díaz, Ester Gloria; Estévez Sarmiento, Francisco; Said, Mercedes; Eiroa Martínez, José Luis; Rubio Sánchez, Sara Issued date: 2020 DOI: 10.3390/ijms21082782 Source: International Journal of Molecular Sciences [ISSN 1661-6596], v. 21 (8), 2782 SJR: 1,455 - Q1 JCR: 5,923 - Q1 SCIE Artículo
Melatonin induces melanogenesis in human SK-MEL-1 melanoma cells involving glycogen synthase kinase-3 and reactive oxygen species Perdomo Díaz, Juan; Quintana, Carlos; González Gordillo,Ignacio; Hernández González, Inmaculada Servanda; Rubio Sánchez, Sara Issued date: 2020 DOI: 10.3390/ijms21144970 Source: International Journal of Molecular Sciences [ISSN 1661-6596], v. 21 (14), 4970, (Julio 2020) SJR: 1,455 - Q1 JCR: 5,923 - Q1 SCIE Artículo
A novel naphthoquinone-coumarin hybrid that inhibits BCR-ABL1-STAT5 oncogenic pathway and reduces survival in imatinib-resistant chronic myelogenous leukemia cells Martín-Rodríguez, Patricia; Guerra, Borja; Hueso-Falcón, Idaira; Aranda Tavío, Haidee Magdalena; Díaz-Chico, Juan Issued date: 2019 DOI: 10.3389/fphar.2018.01546 Source: Frontiers In Pharmacology [ISSN 1663-9812], v. 9, (Enero 2019) SJR: 1,228 - Q1 JCR: 4,225 - Q1 SCIE Artículo
Apoptosis induction and activation of the mitogen-activated protein kinase pathway in human U-937 leukaemia cells by the synthetic flavanone 6-methoxy-2-(naphtalen-1-yl)-chroman-4-one. Estévez, Francisco; Saavedra, Ester; del Rosario, Henoc; Brouard Martín,Ignacio; Hernández Garcés, Judith, et al Issued date: 2019 Source: 39th Spanish Society of Pharmacology Meeting = 39 Congreso de la Sociedad Española de Farmacología, (P002), 2019 Póster de congresos
6′-Benzyloxy-4-bromo-2′-hydroxychalcone is cytotoxic against human leukaemia cells and induces caspase-8- and reactive oxygen species-dependent apoptosis Saavedra Díaz, Ester Gloria; Del Rosario, Henoc; Brouard, Ignacio; Quintana, José; Estévez, Francisco Issued date: 2019 DOI: 10.1016/j.cbi.2018.12.010 Source: Chemico-Biological Interactions[ISSN 0009-2797],v. 298, p. 137-145 SJR: 0,896 - Q1 JCR: 3,723 - Q1 SCIE Artículo
The synthetic flavanone 6-methoxy-2-(naphthalen-1-yl)chroman-4-one induces apoptosis and activation of the MAPK pathway in human U-937 leukaemia cells Saavedra Díaz, Ester Gloria; Del Rosario, Henoc; Brouard, Ignacio; Hernández-Garcés, Judith; García, Celina, et al Issued date: 2019 DOI: 10.1016/j.bioorg.2019.103450 Source: Bioorganic Chemistry [ISSN 0045-2068], v. 94, (Enero 2020) SJR: 0,819 - Q1 JCR: 4,831 - Q1 SCIE Artículo
Natural occurring sesquiterpene lactone Spiciformin induces apoptosis and activation of mitogen-activated protein kinase pathway on human tumour cell lines Rubio Sánchez, Sara; Estevez, Francisco; Saavedra Díaz, Ester Gloria; Said, Mercedes; Eiroa Martínez, José Luis Issued date: 2019 Source: Basic & Clinical Pharmacology & Toxicology [ISSN 1742-7835], v. 125, S54, p. 30-31 SJR: 0,714 - Q2 JCR: 2,651 - Q3 SCIE Actas de congresos
Signal transduction pathways involved in the stimulation of melanogenesis by melatonin in the human melanoma cell line SK-MEL-1 Perdomo, Juan; Quintana, Carlos; Rubio Sánchez, Sara; González Robayna, Ignacio Javier; Hernandez Gonzalez, Inmaculada Issued date: 2019 Source: Basic & Clinical Pharmacology & Toxicology [ISSN 1742-7835], v. 125, p. 29 SJR: 0,714 - Q2 JCR: 2,651 - Q3 SCIE Actas de congresos
Efectos citotóxicos de naftil-chalconas y flavanonas en células de leucemia humana U-937 Saavedra Díaz, Ester Gloria; Del Rosario García, Henoc; Brouard Martín, Ignacio; Hernández Garcés, J.; García, C., et al Issued date: 2019 Source: Libro de Resúmenes del Congreso XXIII Semana Científica "Antonio González". Nuevos Horizontes en Química Orgánica. La Laguna, 1-4 de octubre 2019 [P-25], p. 80 Póster de congresos