Please use this identifier to cite or link to this item: http://hdl.handle.net/10553/77720
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dc.contributor.authorCâmara, Nakitaen_US
dc.contributor.authorSierra Pulpillo, Eva Maríaen_US
dc.contributor.authorFernández Rodríguez, Antonio Jesúsen_US
dc.contributor.authorArbelo Hernández, Manuel Antonioen_US
dc.contributor.authorAndrada Borzollino, Marisa Anaen_US
dc.contributor.authorEspinosa De Los Monteros Y Zayas, Antonioen_US
dc.contributor.authorHerráez Thomas, Pedro Manuelen_US
dc.date.accessioned2021-02-12T12:20:14Z-
dc.date.available2021-02-12T12:20:14Z-
dc.date.issued2020en_US
dc.identifier.issn2045-2322en_US
dc.identifier.urihttp://hdl.handle.net/10553/77720-
dc.description.abstractCapture myopathy (CM), is a syndrome that occurs as the result of the stress during and after capture, handling, restraint, and transport of wild animals. Although CM has been described for many species of cetaceans, characterization of the acute cardiac injury - an important component of this syndrome - are still scarce. In this study, we firstly estimated a normal range for cardiac troponin I (cTnI) on cetaceans. Here, through biochemical analysis (especially of cTnI) and histopathological, histochemical, and immunohistochemical correlations with decreased troponin immunolabelling, we studied the cardiac injury in live-stranded cetaceans. Nine cetaceans which stranded alive on the Canary Islands (January 2016 - June 2019) were included in this study. Sampled individuals presented elevated values of plasma cTnI, which were correlated to histopathological lesions comprised of vascular changes and acute degenerative lesions. Immunohistochemically, injured cardiomyocytes showed a decreased intrafibrillar troponin immunoreaction. This is the first attempt to establish a normal baseline range for cTnI in cetaceans, and the first study comparing plasma biomarkers values with histopathological and immunohistochemical findings. This approach allowed us to demonstrate the degree of cardiac damage as a result of injury, consistent with ischemia–reperfusion lesions. The knowledge gained here could improve decision-making procedures during stressful situations, mainly in live-strandings, handling, and rehabilitation, thereby reducing the mortality of cetaceans.en_US
dc.languageengen_US
dc.relation.ispartofScientific Reportsen_US
dc.sourceScientific reports [EÏSSN 2045-2322], v. 10, article number 1555en_US
dc.subject3105 Peces y fauna silvestreen_US
dc.subject310907 Patologíaen_US
dc.subject.otherCardiomyopathiesen_US
dc.subject.otherDiagnostic markersen_US
dc.subject.otherStranded cetaceansen_US
dc.titleIncreased plasma cardiac troponin I in live-stranded cetaceans: correlation with pathological findings of acute cardiac injuryen_US
dc.typeArticleen_US
dc.identifier.doi10.1038/s41598-020-58497-3en_US
dc.investigacionCiencias de la Saluden_US
dc.type2Artículoen_US
dc.utils.revisionen_US
dc.identifier.ulpgcen_US
dc.contributor.buulpgcBU-VETen_US
dc.description.sjr1,24
dc.description.jcr4,379
dc.description.sjrqQ1
dc.description.jcrqQ1
dc.description.scieSCIE
item.fulltextCon texto completo-
item.grantfulltextopen-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.deptGIR IUSA-ONEHEALTH 3: Histología y Patología Veterinaria y Forense (Terrestre y Marina)-
crisitem.author.deptIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.deptDepartamento de Morfología-
crisitem.author.orcid0000-0001-8307-3915-
crisitem.author.orcid0000-0003-3749-8845-
crisitem.author.orcid0000-0001-5281-0521-
crisitem.author.orcid0000-0002-1623-5010-
crisitem.author.orcid0000-0002-2411-9714-
crisitem.author.orcid0000-0002-7736-3139-
crisitem.author.orcid0000-0001-9316-2882-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.parentorgIU de Sanidad Animal y Seguridad Alimentaria-
crisitem.author.fullNameCamara,Nakita-
crisitem.author.fullNameSierra Pulpillo, Eva María-
crisitem.author.fullNameFernández Rodríguez, Antonio Jesús-
crisitem.author.fullNameArbelo Hernández, Manuel Antonio-
crisitem.author.fullNameAndrada Borzollino, Marisa Ana-
crisitem.author.fullNameEspinosa De Los Monteros Y Zayas, Antonio-
crisitem.author.fullNameHerráez Thomas, Pedro Manuel-
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