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http://hdl.handle.net/10553/75923
Título: | Evaluation of the effects of temporary covered nitinol stent placement in the prostatic urethra: Short-term study in the canine model | Autores/as: | Crisostomo, Veronica Song, Ho Young Maynar Moliner, Manuel Sun, Fei Soria, Federico Lima, Juan Rafael Yoon, Chang Jin Uson-Gargallo, Jesus |
Clasificación UNESCO: | 32 Ciencias médicas 320111 Radiología |
Palabras clave: | Urolume Endoprosthesis High-Risk Hyperplasia Experience Removal, et al. |
Fecha de publicación: | 2007 | Publicación seriada: | CardioVascular and Interventional Radiology | Resumen: | To evaluate the effect of temporary stent placement on the canine prostatic urethra.Retrievable PTFE-covered nitinol stents were placed in the prostatic urethras of 8 beagle dogs under fluoroscopic guidance. Retrograde urethrography was obtained before and after stenting. Retrograde urethrography and endoscopy were performed 1 and 2 months after deployment. The endoscopic degree of hyperplasia was rated on a scale of 0 to 4 (0 = absence, 4 = occlusion). On day 60, stents were removed and urethrography was performed immediately before euthanasia. Pathologic analysis was performed to determine the degree of glandular atrophy, periurethral fibrosis, and urethral dilation.Stent deployment was technically successful in 7 animals, and failed in 1 dog due to a narrow urethral lumen. Complete migration was seen in 2 animals at 1 month, and an additional stent was deployed. On day 30, endoscopy showed slight hyperplasia (grade 1) in 3 animals. On day 60, moderate hyperplasia (grade 2) was evidenced in 4 cases. No impairment of urinary flow was seen during follow-up. Retrieval was technically easy to perform, and was successful in all dogs. The major histologic findings were chronic inflammatory cell infiltrates; prostate glandular atrophy, with a mean value of 1.86 (SD 0.90); periurethral fibrosis, with a mean ratio of 29.37 (SD 10.41); and dilatation of the prostatic urethra, with a mean ratio of 6.75 (SD 3.22).Temporary prostatic stent placement in dogs is safe and feasible, causing marked enlargement of the prostatic urethral lumen. Retrievable covered stents may therefore be an option for bladder outlet obstruction management in men. | URI: | http://hdl.handle.net/10553/75923 | ISSN: | 0174-1551 | DOI: | 10.1007/s00270-007-9006-9 | Fuente: | Cardiovascular And Interventional Radiology [ISSN 0174-1551], v. 30 (4), p. 731-737, (Julio 2007) |
Colección: | Artículos |
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